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Reported treatment of hypercholesterolemia by family physicians in Sweden and Minnesota

Swedish guidelines on treatment of hyperlipidemia recommend higher cut-off levels for initiating treatment than do American guidelines, but are virtually identical for instituting and performing therapy. The aim of this study was to compare family physicians' reported practices in Sweden and Minnesota. We selected random samples of family physicians in southern Sweden and Minnesota for telephone i

Internal ecosystem feedbacks enhance nitrogen-fixing cyanobacteria blooms and complicate management in the Baltic Sea

Eutrophication of the Baltic Sea has potentially increased the frequency and magnitude of cyanobacteria blooms. Eutrophication leads to increased sedimentation of organic material, increasing the Extent of anoxic bottoms and subsequently increasing the internal phosphorus loading. In addition, the hypoxic water volume displays a negative relationship with the total dissolved inorganic nitrogen poo

Nuclear microprobe analysis of the selective boron uptake obtained with BPA in brain tumour tissue

The tumour selective ability of the boron compound boronophenylalanine (BPA), today used in Boron Neutron Capture Therapy in Sweden, has been investigated with the Lund Nuclear Microprobe. The tumour to tissue ratio of the boron concentration, as well as the location of boron within the cells, is critical for the efficiency of the therapy. It is desirable that the boron is accumulated as close as

Hormone replacement therapy: aspects of bleeding problems and compliance

Mitigation of vasomotor symptoms and urogenital problems, along with reductions in osteoporosis and cardiovascular disease, provides the rationale for using hormone replacement therapy (HRT), and the duration of use. However, user surveys have indicated poor compliance with HRT, and that means user time may be less than 12 months, a period unlikely to influence metabolic disorders. The main reason

The Ups and Downs of the Holocene: Exploring Relationships between Global CO2 and Climate Variability in the North Atlantic Region

Popular Abstract in Swedish Jordens klimat har ändrats många gånger genom dess historia. Under de senaste 2,6 miljoner åren har de kontinentala landmassorna varit geografiskt fördelade på så sätt att relativt små skillnader i Jordens omloppsbana kring solen, s.k. orbitala förändringar, har givit upphov till övergångar mellan långvariga, kalla perioder (istider) och kortvariga, varma perioder (mellThis thesis aimed to examine the relationship between climate and atmospheric CO2 concentrations through rapid climate changes during the Holocene. Climate was reconstructed using high-resolution, radiocarbon dated, lake sediment geochemical proxies (magnetic susceptibility, loss-on-ignition, total carbon/nitrogen/sulphur determinations and biogenic silica), vegetational reconstruction (pollen ana

New laboratory lifetime measurements of U II for the uranium cosmochronometer

We present new measurements of radiative lifetimes for six energy levelsof singly ionized uranium, U II, using laser-induced fluorescencetechnique. One of the levels,5f36d7p6M13/2 at 26191 cm-1,decays by a transition at 3859.6 Å. This line has recently beenobserved in the spectrum of the metal-poor star CS1082-001, the firstdetection of uranium outside the solar system. The lambda 3859 line canbe

Effect of commercial breakfast fibre cereals compared with corn flakes on postprandial blood glucose, gastric emptying and satiety in healthy subjects: a randomized blinded crossover trial

BACKGROUND: Dietary fibre food intake is related to a reduced risk of developing diabetes mellitus. However, the mechanism of this effect is still not clear. The aim of this study was to evaluate the effect of commercial fibre cereals on the rate of gastric emptying, postprandial glucose response and satiety in healthy subjects. METHODS: Gastric emptying rate (GER) was measured by standardized rea

Increase in hepatic lipase activity after testosterone substitution in men with hypogonadism of pituitary origin

Ten men with hypogonadism of pituitary origin were studied before and during testosterone substitution therapy with regard to effects on the activities of hepatic lipase (HL) and lipoprotein lipase (LPL) in postheparin plasma, and on plasma lipoprotein concentrations. The mean (+/- SEM) testosterone level increased from 1.8 +/- 0.5 to 16.3 +/- 2.4 nmol/l. The mean activity of HL rose from 327.1 +/

Observation and assignment of the hot band nu(2)+nu(1)(9)-nu(1)(9) in (HCN)(2)

The high-resolution infrared absorption spectrum for (HCN)(2) in the spectral region 3100-3300 cm(-1) is recorded in a static multipass cell at 240 K under equilibrium conditions. The spectrum shows extensive rovibrational structures which are due to the bound C-H stretching vibration band nu(2) of (HCN)(2) and several hot bands associated to nu(2). We manage to assign 63 new rovibrational transit

Overexpression of glial cell line-derived neurotrophic factor using a lentiviral vector induces time- and dose-dependent downregulation of tyrosine hydroxylase in the intact nigrostriatal dopamine system.

The effects of continuous glial cell line-derived neurotrophic factor (GDNF) overexpression in the intact nigrostriatal dopamine (DA) system was studied using recombinant lentiviral (rLV) vector delivery of GDNF to the striatum or substantia nigra (SN) in the rat. Intrastriatal delivery of rLV-GDNF resulted in significant overexpression of GDNF in the striatum (2-4 ng/mg tissue) and anterograde tr

Characterization of contractile P2 receptors in human coronary arteries by use of the stable pyrimidines uridine 5'-O-thiodiphosphate and uridine 5'-O-3-thiotriphosphate

The present study was designed to evaluate the relative contribution of the different contractile P2 receptors in endothelium-denuded human coronary arteries by use of extracellular nucleotides, including the stable pyrimidines uridine 5'-O-3-thiotriphosphate (UTPgammaS) and uridine 5'-O-thiodiphosphate (UDPbetaS). The isometric tension of isolated vessel segments was recorded in vitro, and P2 rec

Dilute-acid hydrolysis for fermentation of the Bolivian straw material Paja Brava

Hydrolysis of the straw material Paja Brava, a sturdy grass characteristic for the high plains of Bolivia, was studied in order to find suitable conditions for hydrolysis of the hemicellulose and cellulose parts. Dried Paja Brava material was pre-steamed, impregnated with dilute sulfuric acid (0.5% or 1.0% by wt), and subsequently hydrolyzed in a reactor at temperatures between 170 and 230 degrees

Small-angle X-ray scattering, light scattering, and NMR study of PEO-PPO-PEO triblock copolymer/cationic surfactant complexes in aqueous solution

The formation of triblock copolymer/surfactant complexes upon mixing a nonionic Pluronic polymer (PEO-PPO-PEO) with a cationic surfactant, hexadecyltrimethylammonium chloride (CTAC), has been studied in dilute aqueous solutions using small-angle X-ray scattering, static and dynamic light scattering, and self-diffusion NMR. The studied copolymer (denoted P123, EO20PO68EO20) forms micelles with a ra