Objective To evaluate if the timing of appearance with respect to disease onset may influence the arthritis presentation pattern in antisynthetase syndrome (ASSD). Methods The patients were selected from a retrospective large international cohort of ASSD patients regularly followed-up in centres referring to AENEAS collaborative group. Patients were eligible if they had an antisynthetase antibody

Maillard reaction is an extensively studied, yet unresolved chemical reaction that occurs as a result of application of the heat and during the storage of foods. The formation of advanced glycation end products (AGEs) has been the focus of several investigations recently. These molecules which are formed at the advanced stage of the Maillard reaction, are suspected to be involved in autoimmune dis

Smart cities promise to generate economic, social and environmental value through the seamless connection of urban services and infrastructure by digital technologies (Hollands 2008, Viitanen and Kingston 2014), but there is scant evidence concerning their ability to enhance social well-being, build just and equitable communities, reduce resource consumption and waste generation, improve environme

The article argues for theorizing and studying the significance of how so-called leaders and followers converge or diverge in their views and understandings of the leadership/followership relations they may be part of. Divergence or misfits may be common yet missed by the researcher who takes only one party’s view of leadership into account and/or assumes that people involved define the relationsh

Ultra-high temperature (UHT) treatment of milk forms a deposit or fouling in the processing equipment that is mineral-based with an enclosed protein network. This study addresses the fundamental mechanisms that control the removal of this deposit. For this purpose, the structural and compositional changes during the cleaning process have been studied. The structure analysis was performed with scan

The present study highlights microbial assimilation of carbon (glucose) and nitrogen (NH3–N) from wastewater using heterotrophic bioconversion process. Experiments were conducted to study the role of heterotrophic microbes towards removal of carbon and nitrogen at varying initial concentrations of carbon (COD, 533 to 1600 mg/l) and nitrogen (NH3–N, 73 to 249 mg/l) keeping the initial biomass of mi

While gene flow can reduce the potential for local adaptation, hybridization may conversely provide genetic variation that increases the potential for local adaptation. Hybridization may also affect adaptation through altering sexual dimorphism and sexual conflict, but this remains largely unstudied. Here, we discuss how hybridization may affect sexual dimorphism and conflict due to differential e

Our purpose is to critically discuss the quality of governability and scrutiny of, as well as insight in, enterprises owned by local government. Our analysis is empirically grounded in an in-depth case study of one of Sweden’s 10 largest municipalities. The ambition is to highlight troublesome areas and danger zones when it comes to public owning of corporations. We have consulted diverse types of

Botulinum neurotoxins (BoNTs) and tetanus neurotoxin (TeNT) are the most potent toxins known and cause botulism and tetanus, respectively. BoNTs are also widely utilized as therapeutic toxins. They contain three functional domains responsible for receptor-binding, membrane translocation, and proteolytic cleavage of host proteins required for synaptic vesicle exocytosis. These toxins also have dist

The potentially tridentate ligand bis[(1-methyl-2-benzimidazolyl)ethyl]amine (2BB) was employed to prepare copper complexes [(2BB)CuI]OTf and [(2BB)CuII(H2O)2](OTf)2 as bioinspired models of lytic polysaccharide copper-dependent monooxygenase (LPMO) enzymes. Solid-state characterization of [(2BB)CuI]OTf revealed a Cu(I) center with a T-shaped coordination environment and metric parameters in the r

In phase-change memory devices, a material is cycled between glassy and crystalline states. The highly temperature-dependent kinetics of its crystallization process enables application in memory technology, but the transition has not been resolved on an atomic scale. Using femtosecond x-ray diffraction and ab initio computer simulations, we determined the time-dependent pair-correlation function o

The transition to a circular economy requires the development of new business models. However, ‘circular’ businesses face a number of barriers when competing in the current ‘linear’ economy, and may require the support of public policies. Public procurement may be applied for this purpose, as it can support emerging markets for reconditioned and remanufactured products. Public procurement can also

Linear or cyclic carbonates as potential monomers for isocyanate-free polyurethanes and polycarbonates were prepared from polyols and dialkylcarbonatesor diphenyl carbonates. This invention was developed to produce linear or cyclic carbonates with or without using catalysts. Polyol compounds were reacted with carbonates such as dimethylcarbonate and diethylcarbonate to produce thecorresponding lin

Under de senaste tre åren har Malmö haft 26 dödsskjutningar. Men efter att polisen börjat sätta hårt mot hårt med ett effektivt spanings­arbete, punktmarkering av tongivande kriminella, samverkan med andra myndigheter och en satsning på avhopparverksamheten har våldet med skjutvapen minskat betydligt, skriver kriminolog Ardavan Khoshnood.Over the past three years, Malmö has witnessed 26 homicides by firearm. Only after that the police responded with vigorous countermeasures like a more effective surveillance, marking high offending and leading criminals, collaboration with other authorities and a massive investment in the defector's program. Ardavan Khoshnood, Criminologist, writes that these measurements have contributed to a sig

This article addresses the dilemmas concerning legislation, individual autonomy and the reality of everyday life for people coping with dementia. We describe and analyse decision-making in relation to older people with dementia in Sweden, within the area of social work regulated by the Social Services Act and the Parental Act. Swedish legislation is based on the individual’s autonomy and capacity