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SARS-CoV-2 non-structural protein 10 (nsp10) is essential for the stimulation of enzymatic activities of nsp14 and nsp16, acting as both an activator and scaffolding protein. Nsp14 is a bifunctional enzyme with the N-terminus containing a 3'-5' exoribonuclease (ExoN) domain that allows the excision of nucleotide mismatches at the virus RNA 3'-end, and a C-terminal N7-methyltransferase (N7-MTase) d
This article discusses theoretical and practical aspects of real-time brain computer interface control methods based on Bayesian statistics. The theoretical aspects include how the data from the brain computer interface can be translated into a Gaussian mixture model that is used in the Bayesian statistics-based control methods. The practical aspects include how the control methods improve the per
This article applies an agenda-setting approach to the impact of New Public Management on health-care reform in Sweden and Finland (1993–2016). A system-level view of agenda setting and New Public Management implementation is used to order the historical data derived from literature reviews of each health reform process. New Public Management is viewed as a hybrid concept rooted in the search for
This paper outlines a guiding principle to address spatial inequalities and injustice in terms of distribution, recognition and participation. The result suggests the emergence of a contractarian principle designed to deal with geographically distributed inequalities, allowing for a monitored market economy applicable not only to cities but to all types of territory. This guiding principle is base
This article investigates Edmund Gosse's Father and Son (1907) through the lens of the queer blue humanities. Drawing on the marine science of the English naturalist Philip Henry Gosse and the Jamaican naturalist Richard Hill, and the fin-de-siècle literary interest in the queer littoral, I show how encounters with coastal life fostered playful, fluid ways of thinking about gender and sexuality. A
This paper discusses the underlying causes behind the masculinization of poverty during the period of 1957–1981 in Sweden. Testable hypotheses are derived from a theoretical framework. The findings suggest that the male role as breadwinner disappeared during the analysed period. Lowly educated men and especially male immigrant labour lost their labour market position when industrial society gave w
Using a flexible spatial panel VAR model for a small-scale labour market system, we investigate the dynamic interdependences between changes in the demographic structure and the labour market performance of a regional economy. With a particular focus on ageing shocks, we describe an increase in the share of elderly in regional population due to exogenous changes in the institutional context, such
This paper aims to discuss polycentrism and its implications. Polycentricity plays a key role in EU Cohesion Policy and has done so since 1999 when the notion was included in the European Spatial Development Perspective. Politically, it emerged as a key tool because of its ability to fuse together the two primary and conflicting perceptions of spatial–economic development, cohesion and competitive
Most rural and peripheral regions in Sweden suffer from an outmigration of young adults and particularly young women are over-represented in this outmigration. The outmigration of young adults in general and young women in particular is headed for the major towns in southern Sweden and the capital city Stockholm. This sex-biased out-migration has been on-going for more than 40 years for some rural
Att människan påverkar klimatet och att utsläpp av växthusgaser värmer planeten är ingen nyhet. Byggsektorn stod 2015 för 18 % av Sveriges totala utsläpp av växthusgaser och 2018 lanserade Bygg- och anläggningssektorn en färdplan för att nå en klimatneutral värdekedja tills år 2045. Tidigare studier har pekat på att majoriteten av klimatpåverkan ifrån flerbostadshus kommer från driftskedet, men seThe emissions of greenhouse gases caused by the construction sector represented 2015 18 % of Sweden’s total greenhouse emissions and the sector had by 2018 published a plan on how to reach a climate neutral value chain by 2045. Studies have shown that the construction phase has become a larger part of the climate impact from new-built multi-family residential buildings than before, in, in relation
The aim of this study is to analyse the initial settlement patterns of 10 immigrant groups during differing times and in circumstances in terms of labour market conditions, structural transformation and changes in the Swedish immigration policy. The regression analyses are based on cross-section period data for the years 1975, 1990 and 2005 at a regional level. In this study, region refers to coun
Adam Smith considered poverty and unemployment as push factors for mi-gration and wages high enough to provide for a worker and his family as a pull factor. Migration as a free mobility of labour leads to an optimal allocation of the factor commodity labour as well as changes of employment which nec-essary to equalise wages between different geographical entities. The conse-quences are not only pr
Electromagnetic waves are widely used in society today for a multitude of applications. Design of electromagnetic devices and applications requires accurate methods for evaluating performance, which often means modern computational methods. While these methods have seen tremendous development in recent decades, it is still very important to perform measurements to validate the performance of devic
Background: For decades, early allogeneic stem cell transplantation (HSCT) has been used to slow neurological decline in metachromatic leukodystrophy (MLD). There is lack of consensus regarding who may benefit, and guidelines are lacking. Clinical practice relies on limited literature and expert opinions. The European Reference Network for Rare Neurological Diseases (ERN-RND) and the MLD initiativ
The Cretaceous - Paleogene boundary (K-Pg, 66 Ma) was a time interval with dramatic changes in the Earth’s climate and the ocean environment. It was characterized by severe disruptions of marine biogeochemical cycles due to a meteorite impact during a time of active volcanism. The extinction of calcifiers, among others, influenced biogeochemical cycles and changed the conditions for carbonate depo
Creosote has been used in Sweden as a wood preservative in buildings since the 19th century. These buildings can function as workplaces, homes, and cultural buildings to which the public has access. Creosote contains polycyclic aromatic hydrocarbons (PAH) which are well known carcinogens. To understand exposure and risks in an indoor environment, it is important to determine air levels of parent P
Rosenberg, Tiina, Sandra D'Urso & Anna Renée Winget, eds. 2021. The Palgrave Handbook of Queer and Trans Feminisms in Contemporary Performance. Cham: Palgrave Macmillan. (541 pages)
