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This meta-review evaluated the possibility of more specified recommendations in antibiotic treatment through a narrowed focus on facial trauma. The aim was to analyze the effect of different regimens of antibiotic in treatment of skeletal trauma to the face. The knowledge mapping was based on existing systematic reviews (SRs) on trials specified in a PICO: Participants (P): Adults and children, di
Background: Studies on long-term exposure to air pollution at high levels suggest an association with increased risk of metabolic syndrome (MetS). We aimed to study this relationship at very low levels, less well-studied, yet of public health importance. Methods: The Swedish CArdioPulmonary bioImage Study (SCAPIS) consists of randomly selected subjects aged 50–64 years from six large cities in Swe
The present work presents extinction strain rates in both premixed and non-premixed cases for n-heptane flames, simulated with different transport formulations and a range of Lennard-Jones parameter sets. Although mixture-average and multi-component transport formulations give similar results, the inclusion of thermal diffusion has a larger impact. Thermal diffusion creates an accumulation of n-he
In the scholarly literature on the geography of transitions, the global innovation systems framework has been used to understand how system resources—such as knowledge, legitimacy, markets, and financial investments—are linked across various geographical scales, contributing to the emergence and performance of an innovation system within a distinct technological field. In this paper, we further de
A global larger foraminiferal turnover (LFT), first identified in the Pyrenees in 1960, occurred around the Paleocene-Eocene boundary. It is characterized by the replacement of Paleocene assemblages dominated by Glomalveolina and Lockhartia (west and east Tethys, respectively), with others typified by Eocene Alveolina and Nummulites. Its relationship with the Paleocene-Eocene Thermal Maximum (PETM
Flame spread through ventilation cavities in timber facades is a serious fire safety concern in tall buildings. In this study, flame behaviour inside a particleboard cavity, resembling the ventilation cavity in a façade system, was investigated. Experiments were conducted with particleboard on one side and an inert panel on the other, across six cavity widths ranging from 10 cm to 25 cm. Variation
Study Region: The Juzhang River Basin in Hubei, China. Study Focus: Precipitation is crucial information in hydrological modelling, and its uncertainty significantly affects the simulation performance. This study constructs a decision tree-based gridded fusion model to integrate multiple precipitation products, generating multi-source fused precipitation products (MSFPPs). The mesoscale hydrologic
Over the past century, Syria and the broader Middle East and North Africa (MENA) region have undergone profound demographic and economic transformations, yet they remain marked by deep regional, ethnic, and gender-based inequalities. These divisions have shaped development trajectories and contributed to social fragmentation, while successive waves of migration carried these dynamics abroad, from
Previous treatment studies have suggested an antidepressant effect of adjunctive probiotics, but more high-quality randomized controlled trials (RCTs) are needed before clinical implementation. The mechanisms underlying putative antidepressant effects of probiotics are not understood, but one possibility is that they are mediated via short-chain fatty acids (SCFAs) − neuroactive bacterial metaboli
We employ a qualitative approach to explore whether and how the use of performance measurement systems differs between public and private providers in Swedish and Finnish primary care, from the perspective of primary care centre managers. The two settings are similar in terms of decentralised healthcare systems but differ in terms of organisation of primary care and governance principles for publi
This paper reports on the challenges of handling menstrual waste in informal settlements in Kisumu, Kenya, and the emerging conflicts between reducing the use of these ‘complicated plastics’ and ensuring human health and dignity. To investigate these interconnections, we draw on a survey conducted among sanitation workers conducting manual pit emptying. We then conducted a knowledge co-production
Objectives: This paper analyzes the educational content of the MinSmerte (MyPain) app, designed to educate patients on postoperative pain management after ambulatory surgery. It examines the complexity of instructional videos, investigating how these relate to the legitimacy claims constructed by educators – defined as assertions about the value of the information based on its relevance, authority
Glycosaminoglycans are structurally diverse polysaccharides that play essential roles in cellular signaling, extracellular matrix organization, and disease progression. Despite their biological importance, the mechanisms of GAG biosynthesis remain not fully understood. This thesis aims to advance mechanistic insight into the biosynthetic machinery and to develop chemical tools and inhibitors targe
The cosmogenic radionuclide 36Cl is a valuable tracer for studying Earth system processes, solar variability and geomagnetic field changes. These applications rely on a comprehensive understanding of 36Cl transport and deposition processes, which are still poorly studied. In this study, we apply a state-of-the-art climate model ECHAM6.3-HAM2.3 to investigate the source distribution and deposition
Matrix gamma distributions are among the most important matrix-variate laws in multivariate statistical analysis, as they encompass the Wishart distributions – the sample covariance distributions under Gaussianity – and provide a natural model for random covariances in Bayesian multivariate methods. A substantial body of literature explores this class of distributions, traditionally characterized
A numerical scheme is presented for solving the Helmholtz equation with Dirichlet or Neumann boundary conditions on piecewise smooth open curves, where the curves may have corners and multiple junctions. Existing integral equation methods for smooth open curves rely on analyzing the exact singularities of the density at endpoints for associated integral operators, explicitly extracting these singu
