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Biofunctionalization of dispense-plotted hydroxyapatite scaffolds with peptides : Quantification and cellular response

Hydroxyapatite (HA) ceramic is a widely used synthetic bone substitute material for the regeneration of bone defects. We manufactured HA scaffolds with adjustable pore sizes and pore geometry by dispense-plotting. In addition, we attached peptides covalently onto the HA surface and are able to simultaneously quantify the amount of covalently attached and adsorbed peptide down to the picomolar rang

Extraction and chromatography of bioactive compounds in complex samples using supercritical CO2 technology

Medical doctors and nutritional specialists recommend to eat healthy foods including fruits and vegetables. Cosmetic experts also recommend to use cosmetic products obtained from natural products. The reason behind this is that natural products from plants contain chemical compounds which can promote health and protect our bodies from several diseases. These chemical compounds are called bioactiveBioactive compounds found in plants have been of interest to man since ancient times. These compounds have the ability to modulate the metabolic processes in our bodies, which suggests that they may promote better health. Bioactive compounds vary in their chemical structure, polarity, stability and biological activity. This diversity makes the study of bioactive compounds challenging from the pers

Irritable bowel syndrome and dysphagia

Functional gastrointestinal disorders constitute a set of gastrointestinal disorders with absence of obvious organic and physiological dysfunctions observed in clinical routine examinations. The functional disorders are divided into many subclasses, e.g., functional esophageal disorders and functional bowel disorders. The diagnoses are set when the patients fulfil the Rome IV criteria after a care

Neuroimaging in patients with dysphagia

With increasing availability of computed tomography (CT) and magnetic resonance imaging (MRI), patients with dysphagia are nowadays often investigated with these modalities in order to localize a possible site of injury causing dysphagia. However, these radiological modalities often reveal some abnormalities especially in elderly patients, and the correlation of these findings with clinical sympto

Stepping on the cracks—transcending the certainties of big data analytics

Every aspect of modern life is dominated by decision-making and the availability of data. We constantly access, process and evaluate data as we navigate complex and uncertain problem spaces. Communication and Information Technologies (ICTs) have developed to a point where it is possible for very large data sets, measured in Exabyte, to be stored across many servers and gathered by many different p

”Leder religionsantropologins utmaningar och forskningsproblematik till nostalgiska elegier och idylliska tankar om ädla vildar?”

Theology, religious studies, the history of religion, and the anthropology of religion have different histories as research disciplines, which explainsdifferences in how they pose research problems and define their research fields. In some respects, the disciplines have a lot in common and may cross-fertilize each other. In this article, I reflect on a theologian's critical review in Religionsvide

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Denne artikel undersøger to typer af litterære karakterer, som skabes i Rushy Rashids Et løft af sløret (2000), Özlem Cekic’ Fra Føtex til Folketinget (2009) og Geeti Amiris Glansbilleder (2016). Den første type er den muslimske kvinde som forbillede for kvindekamp, og den anden er patriarken som produceret af, hvad muslimske debattører har kaldt “rygtesamfundet”. Forfatterne fremstiller den såkal

Aerosol Metal Nanoparticles and their Role in Particle-Assisted Growth of III–V Nanowires

Semiconductor nanowires have properties that make them potentially useful for applications in future electronic, photovoltaic, and optoelectronic devices. A powerful nanowire fabrication technique is the use of a nanoparticle as a preferential nucleation site, from which a nanowire grows. There has been significant progress in nanowire growth assisted by Au nanoparticles over the past 20 years. Ho

Fibrosis and the bladder, implications for function ICI-RS 2017

Aims: Most benign bladder pathologies are associated with an increase of extracellular matrix (ECM—fibrosis) and may progress from formation of stiffer matrix to a more compliant structure. The aims were to summarize current knowledge of the origins of bladder fibrosis and consequences in bladder function. Methods: A meeting at the International Consultation on Incontinence Research Society 2017 c

S100A9-Driven Amyloid-Neuroinflammatory Cascade in Traumatic Brain Injury as a Precursor State for Alzheimer’s Disease

Pro-inflammatory and amyloidogenic S100A9 protein is an important contributor to Alzheimer’s disease (AD) pathology. Traumatic brain injury (TBI) is viewed as a precursor state for AD. Here we have shown that S100A9-driven amyloid-neuroinflammatory cascade was initiated in TBI and may serve as a mechanistic link between TBI and AD. By analyzing the TBI and AD human brain tissues, we demonstrated t

A trip to reach the target? : The labor supply of Swedish Baltic cod fishermen

This paper uses logbook data from Swedish Baltic Sea cod trawlers to investigate the revenue target hypothesis. Incomes from fishing can be highly variable and difficult to predict and it is possible that fishermen set specific revenue targets for their fishing trips to simplify decision making. In this paper a discrete choice stopping model is used where the fishermen must decide to stop or conti

Using panel survey and remote sensing data to explain yield gaps for maize in sub-Saharan Africa

The aim of this paper is to combine remote sensing data with geo-coded household survey data in order to measure the impact of different socio-economic and biophysical factors on maize yields. We use multilevel linear regression to model village mean maize yield per year as a function of NDVI, commercialization, pluriactivity and distance to market. We draw on seven years of panel data on African

Landscape history confounds the ability of the NDVI to detect fine-scale variation in grassland communities

The NDVI is a remotely sensed vegetation index that is frequently used in ecological studies. There is, however, a lack of studies that evaluate the ability of the NDVI to detect fine-scale variation in grassland plant community composition and species richness. Ellenberg indicators characterize the environmental preferences of plant species—and community-mean Ellenberg values have been used to ex

"Zone taken!" : Kunskap, förändring och kulturell gemenskap i mobilspelet Turf

How does a mobile game become a sport related community with its own cultural expressions and norms? This explorative article examines Turf, a mobile game where the players use the GPS function to navigate both a digital map and the physical landscape. By locating digital zones in the landscape, similar to the sport ori- enteering, the player gains points. Around the game various social activities