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Bipolar Monte Carlo simulation of hot carriers in III-N LEDs

We carry out bipolar Monte Carlo (MC) simulations of electron and hole transport in a multi-quantum well light-emitting diode with an electron-blocking layer. The MC simulation accounts for the most important interband recombination and intraband scattering processes and solves self-consistently for the non-quasiequilibrium transport. The fully bipolar MC simulator results in better convergence th

The spleen dictates platelet destruction, anti-platelet antibody production, and lymphocyte distribution patterns in a murine model of immune thrombocytopenia

For many years, splenectomy has been used to treat immune thrombocytopenia (ITP), and this procedure benefits approximately two-thirds of the treated patients. Although splenectomy may raise platelet counts, antibody-coated platelets and cytotoxic T lymphocytes appear to persist or can change over time. To better understand how the spleen may affect anti-platelet immune responses, we used a murine

A comprehensive study of ovine haemostasis to assess suitability to model human coagulation

INTRODUCTION: Similarities in size, anatomy and physiology have supported the use of sheep to model a wide range of human diseases, including coagulopathy. However, coagulation studies involving sheep are limited by the absence of high quality data defining normal ovine coagulation and fibrinolysis.MATERIALS AND METHODS: Full blood examination, routine and specialised coagulation tests, rotational

Peripheral blood monocyte-derived chemokine blockade prevents murine transfusion-related acute lung injury (TRALI)

Transfusion-related acute lung injury (TRALI) is the leading cause of transfusion-related mortality and can occur with any type of transfusion. TRALI is thought to be primarily mediated by donor antibodies activating recipient neutrophils resulting in pulmonary endothelial damage. Nonetheless, details regarding the interactions between donor antibodies and recipient factors are unknown. A murine a

Life satisfaction in patients with and without spinal cord Ischaemia after advanced endovascular therapy for extensive aortic disease at mid-Term follow-up

Objective: Advanced endovascular aortic repair can be used to treat patients with extensive and complex aortic disease who are at risk of spinal cord ischaemia. The aim of this study was to compare whether life satisfaction differs between patients with and without spinal cord ischaemia at mid-Term follow-up. Design: Nested case-control study. Patients: Among patients undergoing advanced endovascu

“A child, a tree” : Challenges in building collaborative relations in a community research project in a Kenyan context

This paper highlights the potential for basing participatory action research on priorities identified by communities. The case builds on a research project by the Social Science Medicine Africa Network (Soma-net) focusing on AIDS prevention among school youth in Kajiado in Kenya during 2003–2006. It became clear from that study just how complex it is to promote open communication on issues of sexu

Intranasal Administration of the Antisecretory Peptide AF-16 Reduces Edema and Improves Cognitive Function Following Diffuse Traumatic Brain Injury in the Rat

A synthetic peptide with antisecretory activity, antisecretory factor (AF)-16, improves injury-related deficits in water and ion transport and decreases intracranial pressure after experimental cold lesion injury and encephalitis although its role in traumatic brain injury (TBI) is unknown. AF-16 or an inactive reference peptide was administrated intranasally 30 min following midline fluid percuss

Tensile behaviour of single-crystal nano-sized Cu beams - geometric scaling effects

In this paper the mechanical response of single-crystal nano-sized Cu beams of different sizes, loaded in displacement controlled tension under constant strain rate is investigated through 3D molecular dynamic simulations using the free-ware LAMMPS. The effects from pure geometric scaling are determined for two different crystallographic orientations of the lattice. Stress-strain curves were recor

Mapping the reduction in gross primary productivity in subarctic birch forests due to insect outbreaks

It is projected that forest disturbances, such as insect outbreaks, will have an increasingly negative impact on forests with a warmer climate. These disturbance events can have a substantial impact on forests' ability to absorb atmospheric CO2, and may even turn forests from carbon sinks into carbon sources; hence, it is important to develop methods both to monitor forest disturbances and to quan

Effect of traumatic brain injury and nitrone radical scavengers on relative changes in regional cerebral blood flow and glucose uptake in rats

Changes in regional cerebral blood flow (rCBF) and glucose metabolism are commonly associated with traumatic brain injury (TBI). Reactive oxygen species (ROS) have been implicated as key contributors to the secondary injury process after TBI. Here, pretreatment with the nitrone radical scavengers (alpha-phenyl-N-tert-butyl nitrone (PBN) or its sulfonated analogue sodium 2-sulfophenyl-N-tert-butyl

The mouthparts enriched odorant binding protein 11 of the Alfalfa Plant Bug Adelphocoris lineolatus displays a preferential binding behavior to host plant secondary metabolites

Odorant binding proteins (OBPs) are proposed to be directly required for odorant discrimination and represent potential interesting targets for pest control. In the notoriously agricultural pest Adelphocoris lineolatus, our previous functional investigation of highly expressed antennal OBPs clearly supported this viewpoint, whereas the findings of the current study by characterizing of AlinOBP11 r

Scanning electron microscopy analysis of the antennal sensilla in therare saproxylic beetle Elater ferrugineus (Coleoptera: Elateridae)

This work provides the first morphological analysis (both at gross and fine level) of the antennal structures in the genusElater (Coleoptera, Elateridae). The typology, number and distribution patterns of the antennal sensilla in the rare saproxylicElater ferrugineus (both male and female) were studied using scanning electron microscopy (SEM). The serrate antennae ofE. ferrugineus consisted of a s

Exome array analysis of ischaemic stroke : results from a southern Swedish study

BACKGROUND AND PURPOSE: Genome-wide association (GWA) studies have identified a few risk loci for ischaemic stroke, but these variants explain only a small part of the genetic contribution to the disease. Coding variants associated with amino acid substitutions or premature termination of protein synthesis could have a large effect on disease risk. We performed an exome array analysis for ischaemi

Recovery after lung transplantation from a patient perspective - proposing a new framework

AIMS: The aims of this study were two-fold: to develop the concept analysis by Allvin et al. from lung recipients' perspective of their post-transplant recovery process and to identify the recovery trajectories including critical junctions in the post-transplant recovery process after lung transplantation.BACKGROUND: Lung transplantation is an established treatment for patients with end-stage lung

Moisture supply Set Point for avoidance of moisture damage in Swedish multifamily houses

From 1950 until 1975 approximately 1.3 million apartments were built in Sweden. Now, a considerable part of these are in need of renovation. This paper is part of an evaluation of a new DCV system developed especially for the renovation of these houses. The DCV automatically regulates the air change rate for each dwelling based on measurements of the indoor air. One of the measured parameters is t

Cultural Diversity and indigenous peoples’ land claims. : Argumentative dynamics and jurisprudential approach in the Americas.

The present study is divided in two differentiable but conceptually interrelated sections. Within the first section (Chapters I, II, and III), the focus is on the assessment of the argumentative logic behind the multiculturalist proposal for equally divided societies, among equally positioned ethno-cultural groups. A critical and analytical review of the multiculturalist argumentative construction

Lower extremity injuries in young floorball players : A prospective study on overuse injuries

Background: Overuse injuries in sports seem to be 1.5 to 2.5 times more common than traumatic injuries in the lower extremity (LE) in children and adolescents. Floorball is the most popular indoor sport in Sweden and is associated with many potential risks of injuries. However, to our knowledge, no previous studies have examined the appearance of injury in young floorball players. Objective: The a