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Patient-relevant outcomes fourteen years after meniscectomy : influence of type of meniscal tear and size of resection

OBJECTIVES: To study long-term patient-relevant outcomes after meniscectomy, a surgical procedure associated with a high risk of knee osteoarthritis (OA). Principal objectives were to compare traumatic with degenerative meniscal tear and partial with subtotal meniscectomy.METHODS: We studied a well-defined cohort of 205 patients who had undergone isolated unilateral meniscectomy between 1983 and 1

Early changes in gene expression in the dorsal root ganglia after transection of the sciatic nerve; effects of amphiregulin and PAI-1 on regeneration.

To characterize the gene activity that may be required for neuronal survival and regeneration, we used the Affymetrix GeneChip Mu74A to screen 12000 genes and expressed sequence tag (EST) mRNA from L4 and L5 mouse dorsal root ganglia (DRG) 12 h and 24 h after sciatic nerve transection. At 12 h, we found 17 upregulated transcripts, and at 24 h, 49 that met our criteria of a significant 2-fold incre

SeaWiFs satellite data analysis of Black Sea water discharge pattern into the Aegean Sea

Satellite data from the SeaWiFS sensor has been used to determine chlorophyll-a contents in the North Aegean Sea using SEADAS 3.3 software. The data is used to extract knowledge on water movements/flow phenomena using chlorophyll as a "tracer" but will also indicate water quality. More than 100 SeaWiFS scenes from 1998 up to 2001 have been analyzed in terms of hydrodynamic phenomena, mainly the tr

The costs of exacerbations in chronic obstructive pulmonary disease (COPD)

Exacerbations are the key drivers in the costs of chronic obstructive pulmonary disease (COPD). The objective was to examine the costs of COPD exacerbations in relation to differing degrees of severity of exacerbations and of COPD. We identified 202 subjects with COPD, defined according to the BTS and ERS criteria. Exacerbations were divided into mild (self-managed), mild/moderate (telephone conta

Generation and Applications of Short-Pulse X-ray Radiation

This thesis summarizes work using hard X-ray radiation on nanosecond and picosecond timescales. The focus is on the experimental part including detailed descriptions of setups for laser pumped - X-ray probe experiments. X-ray diffraction is sensitive to structural properties on the length scale of chemical bonds. The greatest success of X-ray diffraction lies in the determination of crystal struct

Dislocation of Eemian peat in a deglaciation succession: stratigraphical implications for the Neubrandenburg area

A large gravel pit 30 km north of the Pomeranian ice margin has been investigated. Besides gravel, sand, fines and diamicton, several deposits of organic material are present, some of them showing a typical Eemian Pollen- and macroflora. Previous interpretations assume that the sediments below the Eemian peat belong to the Saalian, and those above the peat to the Weichselian. Sorted sediments in t

Activation of c-Src is inversely correlated with biological aggressiveness of breast carcinoma

In order to investigate whether c-Src is involved in carcinogenesis and progression of breast carcinoma, we examined the expression of activated c-Src in tissue sections from surgically resected human breast specimens. First, we confirmed the specificity of the antibody against activated c-Src (Clone 28) using six cell lines established from human breast carcinomas by western blotting. As expected

Comparison of isotropic hardening and kinematic hardening in thermoplasticity

A coupled thermo-mechanical problem is presented in this paper. The constitutive model is based on thermoplastic model for large strains where both kinematic and isotropic hardening are included. It is shown that a non-associated plasticity formulation enables thermodynamic consistent heat generation to be modeled, which can be fitted accurately to experimental data. In the numerical examples the

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Intrvju med professor Linda Williams med anledning av hennes pornografistudie Hard Core.

Synthesis of decaline analogues of isovelleral

Decaline analogues of the bioactive fungal sesquiterpene (+)-isovelleral (1a), retaining the bicyclo[4,1,0]hept-2-en-1,2-dicarbaldehyde system, were prepared, and their cytotoxic and antimicrobial activities were compared with those of the natural product. While the two isomers (+/-)-2 and (+/-)-3 were as active as isovelleral (1a), the isomer (+/-)-4 was approximately 10 times less potent.

Cloning, sequence analysis, and expression of a gene encoding an endoxylanase from Bacillus halodurans S7

The gene encoding an alkaline active xylanase of Bacillus halodurans S7, containing an open reading frame of 1188 nucleotides encoding 396 amino acids, was cloned and expressed in Escherchia coli. On the basis of sequence similarity, possible -10 and -35, ribosome binding, and transcription terminator regions were identified. Analysis of the deduced amino acid sequence revealed that the protein wa

Polybrominated diphenyl ethers at a solid waste incineration plant II: atmospheric deposition

In the second of two papers, the atmospheric polybrominated diphenyl ethers (PBDE) deposition (wet and dry) at a municipal solid waste incineration (MSW) plant with electronics recycling is compared with that at an industrial urban reference site (URS) producing asphalt and concrete. Results of BDE209 and SigmaPBDE excluding BDE209 as representatives of "new" vs. "old" PBDEs are presented. Volume

A catalytic oxidation of sugar by vanadium(IV)

Platinum and other nobel metals have been found to catalyze the complete oxidation of sucrose and other sugars by vanadium(IV) in acid environments. As the redox potential of vanadium(IV)/vanadium(III) differs substantially from that of dioxygen/water, it might be possible to use this reaction to construct a redox type of fuel cell. In the present paper, the requirements on the catalyst are discus