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Evaluating the Impact of COVID-19 on the adoption of virtual care in general practice in 20 countries (inSIGHT) : Protocol and rationale study

Background: In recent decades, virtual care has emerged as a promising option to support primary care delivery. However, despite the potential, adoption rates remained low. With the outbreak of COVID-19, it has suddenly been pushed to the forefront of care delivery. As we progress into the second year of the COVID-19 pandemic, there is a need and opportunity to review the impact remote care had in

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Den styrende målsætning bag de mange danske klimaaftaler gennem de sidste to år, lever ikke op til klimalovens hensigt om, at Danmark skal være et foregangsland. Målet flugter heller ikke med princippet nedfældet i Parisaftalen om fælles, men differentieret ansvar mellem verdens lande i kampen for at begrænse den globale opvarmning til 1,5 grader.

Hypoxia induces radioresistance, epithelial?mesenchymal transition, cancer stem cell?like phenotype and changes in genes possessing multiple biological functions in head and neck squamous cell carcinoma

Hypoxia has been linked with increased resistance to treatment in various solid tumors, including head and neck squamous cell carcinoma (HNSCC). The aim of the present study was to identify genes involved in hypoxia?mediated responses to radiotherapy in HNSCC. A total of three HNSCC cell lines with an epithelial phenotype were selected for this study and cultured under normoxic (21% O2) or hypoxic

Natural language analyzed with AI-based transformers predict traditional subjective well-being measures approaching the theoretical upper limits in accuracy

We show that using a recent break-through in artificial intelligence -transformers-, psychological assessments from text-responses can approach theoretical upper limits in accuracy, converging with standard psychological rating scales. Text-responses use people's primary form of communication -natural language- and have been suggested as a more ecologically-valid response format than closed-ended

Super-Size Me: An Unsuccessful Preregistered Replication of the Effect of Product Size on Status Signaling

Dubois, Rucker, and Galinsky (2012, Experiment 1) found that consumers view larger-size options as a signal of higher status. We conducted a close replication of this finding (N = 415), and observed a nonsignificant effect in the opposite direction (small vs. large product size: doriginal = 1.49, 95%CI [1.09, 1.89], dreplication = 0.09 95%CI [-0.15, 0.33]; medium vs. large: doriginal = 0.89 95%CI

Alternative facts or women’s empowerment? Swedish women’s claims about the health risks of copper IUD use

The internet has radically transformed the way that people seek and share information and, as a consequence, their relationship to established epistemic authorities. It has been stated that ‘the contestation of expertise is perhaps nowhere more pronounced’ than in the field of health (Vuolanto et al., 2020: 508). Health-related information on the internet stems from a variety of actors and sometim

Is Higher-Order Misrepresentation Empirically Plausible? An Argument From Corruption

I present an empirically based argument for the plausibility of misrepresentation as posited by some higher-order theories of consciousness. The argument relies on the assumption that conscious states are generated by processes in the brain. The underlying idea is that if the brain generates conscious states then misrepresentation may occur. The reason for this is that brain states can be corrupte

The effects of virtual reality training in stroke and Parkinson’s disease rehabilitation : a systematic review and a perspective on usability

Background: Virtual Reality (VR) training is emerging in the neurorehabilitation field. Technological advancement is often faster than clinical implementation. Previous reviews stressed the study design and methodological weaknesses of research in the field of VR for neurorehabilitation. Clinically relevant conclusions on implementation in particular patient groups are needed. The aim was to updat

Still engaged – healthcare staff’s engagement when introducing a new eHealth solution for wound management : a qualitative study

Background: eHealth solutions have often been considered favourable for improved effectiveness and quality in healthcare services for wound management. Staff engagement related to organisational changes is a key factor for successful development and implementation of a new eHealth solution, like a digital decision support systems (DDSS). It is essential to understand the engagement process in term

Simple cardiovascular risk stratification by replacing total serum cholesterol with anthropometric measures : The MORGAM prospective cohort project

To assess whether anthropometric measures (body mass index [BMI], waist-hip ratio [WHR], and estimated fat mass [EFM]) are independently associated with major adverse cardiovascular events (MACE), and to assess their added prognostic value compared with serum total-cholesterol. The study population comprised 109,509 individuals (53% men) from the MORGAM-Project, aged 19–97 years, without establish

Review of life science applications using submicron O-PTIR and simultaneous Raman microscopy: a new paradigm in vibrational spectroscopy

The recent advent of Optical Photothermal IR (O-PTIR), has enabled for the first time, submicron infrared microscopy in far-field reflection mode with the combination of Raman for simultaneous, correlative IR+Raman microscopy. These unique and exciting synergistic capabilities are now spawning interest in life science application. A broad range of life science applications, otherwise impossible wi

Validation of Patient Identification Algorithms for Atopic Dermatitis Using Healthcare Databases

Introduction: The use of real-world data offers a possibility to perform large-scale epidemiological studies in actual clinical settings. Despite their many advantages, administrative databases were not designed to be used in research, and the validation of diagnoses and treatments in administrative databases is needed. The primary objective of this study was to validate an existing algorithm base

Human studies of mitochondrial biology demonstrate an overall lack of binary sex differences : A multivariate meta-analysis

Mitochondria are maternally inherited organelles that play critical tissue-specific roles, including hormone synthesis and energy production, that influence human development, health, and aging. However, whether mitochondria from women and men exhibit consistent biological differences remains unclear, representing a major gap in knowledge. This meta-analysis systematically examined four domains an

First National Genomic Epidemiological Study of Neisseria gonorrhoeae Strains Spreading Across Sweden in 2016

The increasing transmission and antimicrobial resistance (AMR) in Neisseria gonorrhoeae is a global health concern with worrying trends of decreasing susceptibility to also the last-line extended-spectrum cephalosporin (ESC) ceftriaxone. A dramatic increase of reported gonorrhea cases has been observed in Sweden from 2016 and onward. The aim of the present study was to comprehensively investigate

Bruce Sterling

This chapter introduces US author, journalist, blogger, and futurist Bruce Sterling. Since his science fiction (sf) debut with the story “Man-Made Self” (1976), Bruce Sterling has so far published eleven novels (plus one in collaboration with William Gibson), over 70 pieces of short fiction (not including dozens of collaborations), and a handful of chapbooks in various media, accruing a number of

Colonial Origins of Modern Bureaucracy? India and the Professionalization of the British Civil Service

This article examines the diffusion of meritocratic practices as a potential instance of policy transfer by scrutinizing the introduction of open and competitive examinations during the mid-nineteenth century in the British Civil Service. Scholars have argued that British reformers were inspired by meritocratic practices in British-ruled India. In order to assess this claim, we combine qualitative