The morphological and biochemical studies of the hippocampal CA1 area in ApoE-deficient mice under the conditionsof dietary intake (8 weeks) with low (LF) and high (HF) fat content were performed. Methods of immunohistochemistry, light and electron microscopy, immunoassay and morphometric as well as statistical analyses were used. It was revealed that the morpho-functional state of the nerve cells

A young man presented unconscious with severe hyponatraemia, hypokalaemia, hypomagnesaemia and metabolic alkalosis. After 4 months of treatment in hospital, the hypomagnesaemia persisted. The patient had no signs of diabetes mellitus, and radiology showed no abnormalities of the kidneys, pancreas or genitourinary tract. A parenteral magnesium load demonstrated renal wasting with increased fraction

Animals interpret their environment by combining information from multiple senses. The relative usefulness of different senses may vary between species, habitats and sexes; yet, how multimodal stimuli are integrated and prioritized is unknown for most taxa. We experimentally assessed foraging preferences of great tits (Parus major) to test whether urban and forest individuals prioritize visual and

This chapter explores how women and families from different minority ethnic backgrounds are treated within the Swedish welfare state by focusing on a space in which the Swedish welfare state meets migrant families in very powerful ways: the delivery room. It begins with a short overview of the Swedish health care system and the Swedish immigration regime, with a particular focus on the changes tha

BACKGROUND: Patients with diabetes have increased rates of major adverse cardiac events (MACEs). We hypothesized that this is explained by diabetes-associated differences in coronary plaque morphology and lipid content. METHODS: In PROSPECT II (Providing Regional Observations to Study Predictors of Events in the Coronary Tree), 898 patients with acute myocardial infarction with or without ST-segme

Background Although physiology-based assessment of coronary artery stenosis using instantaneous wave-free ratio (iFR) and fractional flow reserve (FFR) are established methods of guiding coronary revascularization, its clinical outcome in long-term deferral needs further evaluation, especially with acute coronary syndrome as a clinical presentation. The aim was to evaluate the long-term clinical o

OBJECTIVES: To explore nurses' experiences of a tailored intervention that supported them with knowledge and tools to use during encounters and dialogue with parents with low vaccine acceptance. DESIGN: A qualitative study with in-depth interviews conducted in 2017. Data were analysed using thematic analysis. SETTING: This study was part of a multicomponent intervention targeting Somali parents an

Ipsilateral breast tumor recurrence (IBTR) is a clinically important event, where an isolated in-breast recurrence is a potentially curable event but associated with an increased risk of distant metastasis and breast cancer death. It remains unclear if IBTRs are associated with molecular changes that can be explored as a resource for precision medicine strategies. Here, we employed proteogenomics

Neutrons are widely used as probes of matter to study materials in a broad range of fields from physics, chemistry and medicine to material sciences. Any application utilizing neutrons needs to employ a well-understood and optimized neutron-detector system. This thesis is centered on fundamental aspects of neutron-detector development, including the establishment of the Source Testing Facility at

Context. The current architecture of a given multi-planetary system is a key fingerprint of its past formation and dynamical evolution history. Long-term follow-up observations are key to complete their picture. Aims. In this paper, we focus on the confirmation and characterization of the components of the TOI-969 planetary system, where TESS detected a Neptune-size planet candidate in a very clos

Background: Chronological age is a key clinical determinant ofaortic stiffness. Self-perceived age (SPA) is a strong predictor ofwell-being and long-term health. We aimed to investigate theassociation between SPA, chronological age, and aortic stiffness(vascular ageing) in the general population.Methods: Cross-sectional analysis of a population-based study,Malmö Offspring Study (n=3563). Mean age

Aim As part of its strategic objectives for 2023, EULAR aims to improve the work participation of people with rheumatic and musculoskeletal diseases (RMDs). One strategic initiative focused on the development of overarching points to consider (PtC) to support people with RMDs in healthy and sustainable paid work participation. Methods EULAR's standardised operating procedures were followed. A stee

Objectives To update the Assessment of SpondyloArthritis international Society (ASAS)-EULAR recommendations for the management of axial spondyloarthritis (axSpA). Methods Following the EULAR Standardised Operating Procedures, two systematic literature reviews were conducted on non-pharmacological and pharmacological treatment of axSpA. In a task force meeting, the evidence was presented, discussed

Objectives: To develop EULAR recommendations for screening and prophylaxis of chronic and opportunistic infections in patients with autoimmune inflammatory rheumatic diseases (AIIRD). Methods: An international Task Force (TF) (22 members/15 countries) formulated recommendations, supported by systematic literature review findings. Level of evidence and grade of recommendation were assigned for each

Objectives Evaluate the natural course of anterior cruciate ligament (ACL) healing on MRI within 5 years of acute ACL rupture and compare 2-year and 5-year outcomes based on healing status and treatment group. Methods Secondary analysis of 120 Knee Anterior Cruciate Ligament Nonsurgical vs Surgical Treatment (KANON) trial participants randomised to rehabilitation and optional delayed ACL reconstru

Background: The Nordic Nutrition Recommendations (NNR) are developed to promote public health and to prevent food-related diseases such as obesity and cardiovascular diseases. Objective: To investigate the nutrient intake and adherence to the NNR in a Swedish cohort with abdominal obesity. Design: Dietary intake data were collected using 3-day food diaries and anthropometry and clinical chemistry

This study examines business model innovation in an established firm. We investigate the case of a Swedish utility company that adopted and implemented a business model pattern originating from outside the firm. We draw upon Scandinavian translation theory to understand the micro-level dynamics of how business model innovation unfolds. Our findings show that the business model pattern is disassemb