BackgroundRescue therapy with infliximab (IFX) has been proven effective in a steroid-refractory attack of ulcerative colitis (UC). The long-term efficacy is not well described. AimTo present a retrospective study of IFX as rescue therapy in UC. Primary end points were colectomy-free survival at 3 and 12months. MethodsIn this multicentre study, 211 adult patients hospitalised between 1999 and 2010

Abstract in UndeterminedOver the last decade a great deal of research attention has been paid to the Internet as a potential vehicle for civic and/or political engagement among young people. Many of these analyses have been looking (or perhaps hoping) for a simple cause-and-effect relationship. Young people seem uninterested in traditional forms of politics, but they are very interested in Interne

Objective: To evaluate if remission induced by low-dose prednisolone during the first 2 years of rheumatoid arthritis (RA) in the BARFOT glucocorticoid (GC) study had a sustained effect on radiological damage for a total of 4 years. Methods: A total of 150 of 211 eligible patients with RA who had been randomised to the 7.5 mg prednisolone group ( P) or no prednisolone group (NoP) in addition to th

Introduction: This paper reports results from an ethnographic study of teacher trainees’ information activities in digital, group-based learning and their relation to the interplay between use and appropriation of digital tools and the learning environment. Method. The participants in the present study are 249 pre-school teacher trainees in Sweden. Three key informants and their teams were followe

The study investigates how the early nineteenth century invention of comparative-historical linguistics affected European ethnohistoric thought, and how this process altered ethnohistorical research on the early, pre-Christian history of the Nordic region. The case study of the Nordic region (Denmark, Iceland, Norway, Sweden, Finland and Estonia) includes the discipline histories of Finno-Ugric st

The Coulomb excitation experiment to study electromagnetic properties of low-lying states in Ca-42 with a focus on a presumably superdeformed band was performed at the Laboratori Nazionali di Legnaro in Italy using the gamma-ray spectrometer AGATA Demonstrator coupled to the DANTE charged particle detector array. First results are presented, including the refinement of the Ca-42 level scheme.

The Medipix detector is the first device dedicated to measuring mixed-field radiation in the CMS (Compact Muon Solenoid) experiment cavern and able to distinguish between different particle types. Medipix2-MXR chips bump bonded to silicon sensors with various neutron conversion layers developed by the IEAP CTU in Prague were successfully installed for the 2008 LHC start-up in the CMS experimental

Purpose: We tested the hypothesis that low vitamin D is associated with benign prostatic hyperplasia. We also studied whether body composition, sex hormones, serum sex hormone-binding globulin, albumin corrected serum calcium, adiponectin and lipid status are associated with benign prostatic hyperplasia. Materials and Methods: We investigated 184 representative, randomly selected men 72 to 76 year

This study assessed the ability of the tongue tip to accurately select intra-oral sensors embedded in a upper palatal interface of 19 able-bodied volunteers. Tongue selectivity performance measures were determined for three different tongue-computer interface layouts. Assessment of intra-oral target selection speed and accuracy revealed that performance was dependent on the location and distance b

The nuclear structure of neutron-rich N>126 nuclei has been investigated following their production via relativistic projectile fragmentation of a E/A=1 GeV U-238 beam. Metastable states in the N=128 isotones Hg-208 and Tl-209 have been identified. Delayed gamma-ray transitions are interpreted as arising from the decay of I-pi=(8(+)) and (17/2(+)) isomers, respectively. The data allow for the so f

Rheumatoid arthritis (RA) is an autoimmune disease characterized by chronic inflammation of the peripheral joints that eventually leads to cartilage destruction and bone erosion. The causes of RA remain largely unknown, but considerable evidence suggests a multifactorial aetiology involving both environmental and genetic factors. Large efforts have been directed towards the understanding of the mo

Popular Abstract in Swedish Leukemi är en cancersjukdom i blod och benmärg som karakteriseras av en störd blodbildning. Vid normal blodbildning delar sig ett begränsat antal omogna blodceller så kallade blod stamceller (eller hematopoietiska stamceller) och mognar till funktionella blodceller. Genom att dela sig utan att mogna har stamcellerna även potential till at förnya sig själva. När nya stamAcute myeloid leukemia (AML) is a malignant disorder of the blood system. Hematopoietic stem cells (HSCs) supply and maintain this system by differentiating via intermediates into lineage-restricted progenitors that strongly proliferate to keep up with the high turn-over of mature blood cells. In AML, the mechanisms controlling differentiation and proliferation of myeloid cells are disturbed leadi

When building shape models, it is first necessary to filter out the similarity transformations from the original configurations. This is normally done using Procrustes analysis, that is minimising the sum of squared distances between the corresponding landmarks under similarity transformations. In this article we propose to align shapes using the Minimum Description Length (MDL) criterion. Previou

Divergent-light halos are produced when light from nearby light sources is scattered by ice crystals in the atmosphere. We present a theory of divergent-light halos leading to an improved algorithm for the simulation of such halos. Contrary to the algorithm that we presented earlier for simulating such halos, the new algorithm includes a mathematically rigorous weighting of the events. The compute

This study investigates utilization of the Internet in the rehabilitation of people on long-term sick leave with chronic pain and/or burnout. Fifty-five people were randomly assigned to two groups: a treatment group (n = 27) that participated in a rehabilitation course over the Internet and a waiting list group (n = 28). The goals were to improve participants' health and increase quality of life,