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The role of p-c-Jun in survival and outgrowth of developing sensory neurons
c-jun activation has been implicated not only in neuronal apoptosis, but also in survival and regeneration. This Janus facet of c-Jun activation could be related to neuronal cell type or to the developmental stage of the neuron. We investigated c-Jun activation in E18 sensory neurons. Cultures of rat dorsal root ganglia neurons were maintained with or without the addition of nerve growth factor or
Rapid adaptive divergence between ecotypes of an aquatic isopod inferred from F-Q analysis.
Abstract Divergent natural selection is often thought to be the principal factor driving phenotypic differentiation between populations. We studied two ecotypes of the aquatic isopod Asellus aquaticus which have diverged in parallel in several Swedish lakes. In these lakes, isopods from reed belts along the shores colonized new stonewort stands in the centre of the lakes and rapid phenotypic chang
Rewired: Exploring Religious Conversion
Physiological and biochemical principles underlying volume-targeted therapy--the "Lund concept".
Thermal analysis of plate condensers in presence of flow maldistribution
Flow maldistribution in plate heat exchangers causes deterioration of both thermal and hydraulic performance. The situation becomes more complicated for two-phase flows during condensation where uneven distribution of the liquid to the channels reduces heat transfer due to high liquid flooding. The present study evaluates the thermal performance of falling film plate condensers with flow maldistri
Influence of cold acclimation on the mechanical strength of carrot (Daucus carota L.) tissue
We have investigated the influence of cold acclimation on the mechanical strength of carrot (Daucus carota L.) taproots. Changes in the mechanical strength were monitored when cold acclimation was induced in carrot plants cultivated in a growth chamber under strict climate control and in taproots harvested from field cultivation, where the plants had been exposed to the natural variations in clima
Panel cointegration tests of the Fisher effect
Most empirical evidence suggests that the Fisher effect, stating that inflation and nominal interest rates should cointegrate with a unit slope on inflation, does not hold, a finding at odds with many theoretical models. This paper argues that these results can be attributed in part to the low power of univariate tests, and that the use of panel data can generate more powerful tests. For this purp
Dose response evaluation of a low-density normoxic polymer gel dosimeter using MRI.
Gene expression profiling of human placentas from preeclamptic and normotensive pregnancies.
The aim of this study was to investigate patterns of gene expression in placental samples from patients with preeclampsia (PE), persistent bilateral uterine artery notching (without PE), and normal controls. This study included placental tissue from nine women with PE, seven with uncomplicated pregnancies and five with bilateral uterine artery notching in Doppler velocimetry tracings. Human cDNA m
Effects of a goal-oriented rehabilitation program in mild cognitive impairment: A pilot study
Background: Memory disturbance, deficient concentration, and fatigue are symptoms seen in amnestic mild cognitive impairment (MCI) as well as in mild traumatic brain injury (TBI). The aim of this study was to assess if an established rehabilitation program commonly used in TBI can aid MCI patients to develop compensatory memory strategies that can improve their cognition, occupational performance,
Reply to Comment on: 'A numerical comparison of 2D resistivity imaging with 10 electrode arrays' by T. Dahlin and B. Zhou
Nanotubes: The logical choice for electronics?
The demonstration of switches and logic devices made purely from carbon nanotubes, without the need for an external gate, puts nanotubes at the forefront of next-generation electronics.
Efficacy of maintenance treatment with naltrexone for opioid dependence: a meta-analytical review
Cutaneous sensory nerve fibers are decreased in number after peripheral and central nerve damage.
Two dermatologic patients displaying peripheral and central nerve damage, respectively, are described. Cutaneous nerve fibers in both patients were studied in skin biopsy specimens taken from neuropathic areas and from the contralateral side, immunocytochemistry being applied to a pan-neuronal marker, a protein gene-product (PGP 9.5). One of the patients, suffering from compression of the ulnar ne
The Immunoglobulin D-Binding Protein MID from Moraxella catarrhalis Is Also an Adhesin.
Structural and functional studies of complement inhibitor C4b-binding protein.
C4b-binding protein (C4BP) is a potent inhibitor of the classical pathway of the complement system. This large plasma glycoprotein consists of seven identical a- chains and a unique b-chain held together by disulphide bridges. Both types of subunits are composed almost exclusively of complement control protein domains (CCPs). Using homology-based computer modelling and mutagenesis of recombinant p
Radiative Cycle with Stimulated Emission from Atoms and Ions in an Astrophysical Plasma
We propose that a radiative cycle operates in atoms and ions located ina rarefied gas in the vicinity of a hot star. Besides spontaneoustransitions the cycle includes a stimulated transition in one very weakintermediate channel. This radiative bottleneck creates apopulation inversion, which for an appropriate column density results inamplification and stimulated radiation in the weak transition. T
Biogas production from llama and cow manure at high altitude
Methane production from llama and cow manures from the Bolivian high plateau (The "Altiplano") was studied using a parallel reactor set-up consisting of 10 lab-scale biogasifiers. The effects of pressure (495 and 760 mmHg), temperature (11 and 35 degrees C), hydraulic retention time (20 and 50 days), and manure content in the slurry (10%, 20% and 50%) were evaluated with respect to productivity an
Combined hydrophobic-metal binding fusion tags for applications in aqueous two-phase partitioning
In this work, we studied the influence of fusion affinity tags containing both hydrophobic and histidines residues on the partitioning of the green fluorescent protein, GFPuv, in aqueous two-phase system. The tags were fused to the N-terminal of GFPuv and tested by immobilized metal affinity partitioning, in a PEG/salt system. The presence of both types of residues in the tag increased the partiti