This work covers qualitative and quantitative requirements with regard to material propertiesfor cutting tools to be able to resist and balance the various interactive mechanisms that causethe wear of the cutting edge and put limits its tool life. In metal cutting, tool life T combinedwith the cutting data (cutting speed, feed and depth of cut) controls largely the manufacturingcost and related co

Purpose: To investigate the management of TaG3 tumours of the urinary bladder using nationwide population-based data in relation to the prevailing guidelines, patients’ characteristics, and outcome. Materials and methods: The Bladder Cancer Data Base Sweden (BladderBaSe), including data from the Swedish National Register for Urinary Bladder Cancer (SNRUBC), was used to study all patients with TaG3

Stress intensity factors are calculated for long plane cracks with one tip interacting with a region of graded material characteristics. The material outside the region is considered to be homogeneous. The analysis is based on assumed small differences in stiffness in the entire body. The linear extent of the body is assumed to be large compared with that of the graded region. The crack tip, incluStress intensity factors are calculated for long plane cracks with one tip interacting with a region of graded material characteristics. The material outside the region is considered to be homogeneous. The analysis is based on assumed small differences in stiffness in the entire body. The linear extent of the body is assumed to be large compared with that of the graded region. The crack tip, inclu

The behaviour of the stress intensity factor is investigated for a long plane crack with one tip interacting with a strip of graded elastic properties. The material outside the strip is postulated to be homogeneous linear elastic and the material in the graded region is assumed to have continuous change of modulus of elasticity. Changes of the Poisson’s ratio are ignored. The body is assumed to be

The present research is developed in the frame of the R&D project GMES4Mining, which aims to support particular tasks within the different phases of a mining life cycle [1]. During the exploitation and after the closure of the mine, environmental and civil impacts may happen, due to changes in the compacting properties of the soil related to mining activities. In this paper, we focus in the em

The hMRI toolbox is an open-source toolbox for the calculation of quantitative MRI parameter maps from a series of weighted imaging data, and optionally additional calibration data. The multi-parameter mapping (MPM) protocol, incorporating calibration data to correct for spatial variation in the scanner’s transmit and receive fields, is the most complete protocol that can be handled by the toolbox

Biogenic volatile organic compound (BVOC) emissions from subarctic ecosystems have shown to increase drastically in response to a long-term temperature increase of only 2°C. We assessed whether this increase takes place already after 3 years of warming and how the increase changes over time. To test this, we measured BVOC emissions and CO2 fluxes in a field experiment on a subarctic wet heath, whe

Several concurrent developments are shaping the future of plastics. A transition to a sustainable plastics system requires not only a shift to fossil-free feedstock and energy to produce the carbon-neutral building blocks for polymers used in plastics, but also a rational design of the polymers with both desired material properties for functionality and features facilitating their recyclability. B

The purpose of the present experiments was to study the effects of a combined cholinergic and serotonergic denervation of the rat forebrain on spatial learning using the Morris water maze task. Experiment 1 compared the acute effects of a radiofrequency lesion of the septum, an intraventricular 5,7-dihydroxytryptamine (5,7-DHT) lesion, and a combined septal plus 5,7-DHT lesion. Although the 5,7-DH

Grafts of five different types of central cholinergic neurons, from the septal-diagonal band region, the nucleus basalis magnocellularis region (NBM), the striatum, the pontomesencephalic tegmentum of the brainstem, and the spinal cord, were compared with respect to their ability to grow and to reinnervate the cholinergically denervated hippocampal formation of adult rats. The areas were dissected

The survival and function of cross-species (mouse-to-rat) grafts of fetal mesencephalic dopamine (DA) neurons, implanted as a cell suspension in the striatum of rats with lesions of the mesostriatal DA system, have been studied in animals with and without immunosuppression induced by Cyclosporin A (CyA). At 6 weeks after grafting 3 out of 7 non-CyA treated animals showed some degree of graft survi