These guidelines for the management of congenital ichthyoses have been developed by a multidisciplinary group of European experts following a systematic review of the current literature, an expert conference held in Toulouse in 2016, and a consensus on the discussions. These guidelines summarize evidence and expert-based recommendations and intend to help clinicians with the management of these ra

Rural water supplies have traditionally been overshadowed by urban ones. That must now change, as the Sustainable Development Goals calls for water for all. The objective of the paper is to assess the current access to and the perceived water quality in villages with various types of water supply. The survey was carried out during July⁻December 2017 in four villages in central Kazakhstan. Overall,

Mexico has the most transited migratory corridor in the world . The complex migratory flows transiting the country—mainly Mexican, Central and South Amer- ican—have historically been perceived as economic and male . Scholars have not- ed as problematic the categorisation of the ‘labour migrant’ as being exclusive- ly voluntary. It has been demonstrated that framing agency through simplified unders

Background: The mechanically expandable Lotus Valve System is a fully repositionable and retrievable valve with an adaptive seal to minimize paravalvular leak (PVL). The aim of this study was to evaluate the short- and long-term safety and efficacy of the new device with focus on a new implantation technique to reduce the need for a permanent pacemaker (PPM) post procedure. Methods: We performed

Mexico is the most transited corridor in the world. Beyond borderlands, human rights abuses committed against migrants pervade across transit communities and routes. In the interior of Mexico, not only at borders, the criminalization of migration has occurred having as a backdrop violence, xenophobia and insecurity in transit communities. Transit communities have developed complex relationships wi

Background: Single-operator, per-oral cholangiopancreatoscopy (SOPCP) enables direct biliopancreatic ductal visualization, targeted tissue sampling, and therapeutic intervention. At Karolinska University Hospital, SOPCP was introduced early and has since been extensively utilized according to a standardized protocol. We analysed the clinical value of SOPCP in the diagnosis and treatment of biliopa

Objective: Long-term oxygen therapy (LTOT) during 15 h/day or more prolongs survival in patients with chronic obstructive pulmonary disease (COPD) and severe hypoxemia. No randomized controlled trial has evaluated the net effects (benefits or harms) from LTOT 24 h/day compared with 15 h/day or the effect in conditions other than COPD. We describe a multicenter, national, phase IV, non-superiority,

By using a phenomenologically successful Woods-Saxon potential, I study the shape and shell structure of (A) neutron drip line nuclei with 10≤N≤60, (B) neutron-rich nuclei related to the r process with 40≤N≤90, and (C) one-particle spectra in the potential provided by the nucleus Fe70 as a representative of so-called N=40 "island of inversion" (IoI) nuclei. First, the shell structure that is uniqu

Measurements of inclusive and direct photon production at midrapidity in pp collisions at s=2.76 and 8 TeV are presented by the ALICE experiment at the LHC. The results are reported in transverse momentum ranges of 0.47 GeV/c is at least one σ above unity and consistent with expectations from next-to-leading order pQCD calculations. © 2019 CERN.

Objectives The aim of this study was to investigate if occupational exposure to inorganic particles or welding fumes during pregnancy is associated with negative birth outcomes. Design A prospective national cohort study. Setting All single births from 1994 to 2012 in Sweden. Information on birth weight, preterm birth, small for gestational age, smoking habits, nationality, age, occupation, absenc

We investigate the effects of a ℤ 2 symmetry in the CP-conserving Two-Higgs-Doublet-Model (2HDM); which is often imposed to prevent Flavor-Changing-Neutral-Currents (FCNCs) at tree-level. Specifically, we analyze how a breaking of the ℤ 2 symmetry spreads during renormalization group evolution; employing general 2-loop renormalization group equations that we have derived. Evolving the model fro

Background Native aortic and mitral valve infective endocarditis (AVE and MVE, respectively) are usually grouped together as left-sided native valve infective endocarditis (LNVE), while the differences between AVE and MVE have not yet been properly investigated. We aimed to compare AVE and MVE in regard to patient characteristics, microbiology and determinants of survival. Methods We conducted a r

Objectives: The aim of this study was to analyze drain fluid, blood, and urine simultaneously to follow the long-term release of vancomycin from a biphasic ceramic carrier in major hip surgery. Our hypothesis was that there would be high local vancomycin concentrations during the first week with safe low systemic trough levels and a complete antibiotic release during the first month.Methods: Nine

Flight activity recorders have recently confirmed that alpine and common swifts spend the majority of their non-breeding period on the wing, which may last 6–10 months. Here we test the hypothesis that the closely related pallid swift, a species with a breeding distribution around the Mediterranean, lead a similar aerial life-style during its migration and wintering periods. The pallid swift usual

Using the class of information set decoding algorithms is the best known way of decoding general codes, i.e. codes that admit no special structure, in the Hamming metric. The Stern algorithm is the origin of the most efficient algorithms in this class. We consider the same decoding problem but for a channel with soft information. We give a version of the Stern algorithm for a channel with soft inf

Background Due to improved care, the numbers of patients with tetralogy of Fallot (ToF) are increasing. However, long-term morbidity and need for reinterventions are concerns and also address issues of quality of life (QoL). Methods Patients with ToF and valid EuroQol-5 dimensions questionnaire (EQ-5D) were identified in the national Swedish register on congenital heart disease. EQ-5D index was ca

Climate change's effect on sea surface temperature (SST) at the regional scale vary due to driving forces that include potential changes in ocean circulation and internal climate variability, ice cover, thermal stability, and ocean mixing layer depth. For a better understanding of future effects, it is important to analyze historical changes in SST at regional scales and test prediction techniques