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Computational Analysis of Pin-Fin Arrays Effects on Internal Heat Transfer Enhancement of a Blade Tip Wall

Cooling methods are strongly needed for the turbine blade tips to ensure a long durability and safe operation. Improving the internal convective cooling is therefore required to increase the blade tip life. A common way to cool the tip is to use serpentine passages with 180-deg turns under the blade tip cap. In this paper, enhanced heat transfer of a blade tip cap has been investigated numerically

Modelling natural disturbances in forest ecosystems: a review

Natural disturbances play a key role in ecosystem dynamics and are important factors for sustainable forest ecosystem management. Quantitative models are frequently employed to tackle the complexities associated with disturbance processes. Here we review the wide variety of approaches to modelling natural disturbances in forest ecosystems, addressing the full spectrum of disturbance modelling from

Association of a multibiomarker disease activity score at multiple time-points with radiographic progression in rheumatoid arthritis: results from the SWEFOT trial.

In rheumatoid arthritis (RA), predictive biomarkers for subsequent radiographic progression (RP) could improve therapeutic choices for individual patients. We previously showed that the multibiomarker disease activity (MBDA) score in patients with newly diagnosed RA identified patients at risk for RP. We evaluated the MBDA score at multiple time-points as a predictor of RP during 2 years of follow

Rapid and direct determination of fructose in food: A new osmium-polymer mediated biosensor

This paper describes the development and performance of a new rapid amperometric biosensor for fructose monitoring in food analysis. The biosensor is based on the activity of fructose dehydrogenase (FDH) immobilised into a carbon nanotube paste electrode according to two different procedures. The direct wiring of the FDH in a highly original osmium-polymer hydrogel was found to offer a better enzy

Diagnosens Janusansikte: exemplet adhd. En livsberättelse om oro, sökandet efter kontroll och sammanbrott

Various neuropsychiatric disorders are a common feature of today. Not least the adhd diagnosis. The aim of the article is to provide an alternative model for understanding adhd which differ from the otherwise dominant neurobiological perspective. The method used was to let a person – Anders who is almost 30 years – tell about his life and his adhd diagnosis. Through the told story it becomes clear

Metabolite Profiling Identifies Pathways Associated With Metabolic Risk in Humans

Background-Although metabolic risk factors are known to cluster in individuals who are prone to developing diabetes mellitus and cardiovascular disease, the underlying biological mechanisms remain poorly understood. Methods and Results-To identify pathways associated with cardiometabolic risk, we used liquid chromatography/mass spectrometry to determine the plasma concentrations of 45 distinct met

Extensive Gamma-ray Spectroscopy of Band Structures in 62Zn

An experimental study of the Zn-62 nucleus has been performed by combining the data sets from four fusion-evaporation reaction experiments. Apart from the previously published data, the present results include ten new rotational band structures and two more superdeformed bands. The Gammasphere Ge-detector array in conjunction with the 4 pi charged-particle detector array Microball allowed for the

Numerical experiments in fire science: a study of ceiling jets

In this paper, a numerical experiment, consisting of 90 simulations in Fire Dynamics Simulator (FDS), is conducted for two different purposes. Firstly, numerical experiments are explored as a research method in fire science, and it is demonstrated that numerical experiments could be used as a complement to traditional fire experiments in fire science research. Secondly, an evaluation of previously

A snapshot into the terrestrial ecosystem of an exceptionally well-preserved dinosaur (Hadrosauridae) from the Upper Cretaceous of North Dakota, USA

A palynological investigation of sedimentary rocks enclosing an exceptionally well-preserved fossil dinosaur (Hadrosauridae) discovered in the upper part of the Hell Creek Formation in south western North Dakota was conducted in order to document the immediate paleoenvironment of this dinosaur. The specimen, an Edmontosaurus annectens is remarkable in having exceptional three-dimensional preservat

Quantitative measurement of fluorescence brightness of single molecules

Single-molecule fluorescence spectroscopy and imaging probe many characteristics of the fluorescence from individual molecules like relative intensity, polarization, lifetime and spectrum. However, such an important and fundamental parameter as absolute fluorescence intensity (or in other words fluorescence brightness), which is proportional to the absorption cross section and fluorescence quantum

What's in the Black Box of Arthritis Rehabilitation? A Comparison of Rehabilitation Practice for Patients with Inflammatory Arthritis in Northern Europe

Background: In evaluating complex interventions, it is a challenge for researchers to provide transparent reporting of the intervention content with sufficient detail and clarity such that effects can be compared across studies or countries. Objective: To describe and compare the content of current rehabilitation for patients with inflammatory arthritis across 4 northern European countries. Patien

Assessing re-introductions of the African Wild dog (Lycaon pictus) in the Limpopo Valley Conservancy, South Africa, using the stochastic simulation program VORTEX

The African wild dog (Lycaon pictus) is one of Africa's most endangered species and therefore classified as endangered by IUCN. Earlier distributions included most of Africa but currently the African wild dog only has populations larger than 300 individuals in three countries (Botswana, Tanzania and South Africa). In 1998, a plan was launched in South Africa to manage sub-populations of the Africa

Race/Ethnic Differences in the Associations of the Framingham Risk Factors with Carotid IMT and Cardiovascular Events.

Clinical manifestations and outcomes of atherosclerotic disease differ between ethnic groups. In addition, the prevalence of risk factors is substantially different. Primary prevention programs are based on data derived from almost exclusively White people. We investigated how race/ethnic differences modify the associations of established risk factors with atherosclerosis and cardiovascular events

Study of energy response and resolution of the ATLAS barrel calorimeter to hadrons of energies from 20 to 350 GeV

A fully instrumented slice of the ATLAS detector was exposed to test beams from the SPS (Super Proton Synchrotron) at CERN in 2004. In this paper, the results of the measurements of the response of the barrel calorimeter to hadrons with energies in the range 20-350 GeV and beam impact points and angles corresponding to pseudo-rapidity values in the range 0.2-0.65 are reported. The results are comp

Chemogenetics, Induced Neurons and Pluripotent Stem Cells: Towards Advanced Gene and Cell Therapies Targeting Epilepsy

The complexity of the central nervous system and existence of the blood-brain barrier often causes difficulties for traditional pharmacological treatments of neurological diseases. This thesis explores the feasibility and potential for novel gene and cell therapy approaches, which hold better promise for neurological disorders, while particularly targeting epilepsy. Epilepsy is a multifactorial ne