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Removal of formic acid from wastewater using three-phase three-dimensional electrode reactor
A new electrochemical reactor, three-phase three-dimensional electrode reactor, was designed and used to investigate the removal of formic acid from simulated wastewater. The experimental results were assessed in term of Chemical Oxygen Demand (COD) removal efficiency. The results showed that the three-phase three-dimensional electrodes could effectively remove formic acid. Its COD removal efficie
Impact of inhibitor epitope profile on the neutralizing effect against plasma-derived and recombinant factor VIII concentrates in vitro.
Ruthenium-Manganese Complexes for Artificial Photosynthesis: Factors Controlling Intramolecular Electron Transfer and Excited-State Quenching Reactions
Continuing our work toward a system mimicking the electron-transfer steps from manganese to P680+ in photosystem II (PS II), we report a series of ruthenium(II)-manganese(II) complexes that display intramolecular electron transfer from manganese(II) to photooxidized ruthenium(III). The electron-transfer rate constant (kET) values span a large range, 1 × 105-2 × 107 s-1, and we have investigated di
Ontogenesis of within-session locomotor habituation in the open field.
Habituation signifies a decreased response to a constant or repeated stimulus or environment. Although habituation is a fundamental form of nonassociative learning, little is known about its ontogenesis. Here, locomotor activity of postnatal ferrets within individual open field sessions was quantitatively analysed. The patterns of activity revealed a gradual shift across developmental time between
Adsorption Mechanisms of EDTA at the Water-Iron Oxide Interface: Implications for Dissolution
The interactions between chelating agents and metal oxide particles play important roles for the distribution and availability of metal ions in aquatic environments. In this work, the adsorption of ethylenediaminetetraacetate (EDTA) onto goethite (alpha-FeOOH) was studied as a function of pH, time, and background electrolyte concentration at 25.0 degrees C, and the molecular structures of the surf
MEK1/2 inhibition attenuates vascular ET(A) and ET (B) receptor alterations after cerebral ischaemia.
Cerebral ischaemia is associated with elevated levels of endothelin B (ETB) receptors in the ipsilateral middle cerebral artery (MCA). This up-regulation of ET receptors occurs via de novo transcription involving mitogen-activated protein kinases (MAPK). The aim of this study was to examine the effect of inhibition of the MAP kinase/ERK kinase (MEK)1/2 on ET receptor alteration, brain damage, and
Infarct volume and functional outcome after pre- and postoperative administration of metyrapone, a steroid synthesis inhibitor, in focal brain ischemia in the rat
High blood levels of glucocorticoids are associated with increased mortality, confusion and poor functional outcome in stroke patients. It has been proposed that inhibition of glucocorticoids in acute stroke might be beneficial, but experimental data are conflicting and no long-term follow-up study has been reported. We have studied whether pre- or postoperative administration of metyrapone, a ste
The costs of treating glaucoma with combinations of topical drugs in Spain
PURPOSE. This study describes the treatment in ordinary clinical practice in Spain of patients with glaucoma with a two-drug combination therapy. The authors present the treatment outcome as end-of-period intraocular pressure (IOP) and the calculated direct medical costs over a 2-year period. METHODS. Data were extracted retrospectively from patient charts recording the use of all medical resource
mRNA for pancreatic uncoupling protein 2 increases in two models of acute experimental pancreatitis in rats and mice
Uncoupling-protein 2 (UCP2) is a mitochondrial protein that appears to be involved in cellular oxidant defense and in the regulation of oncotic cell death, both of which are important features of acute pancreatitis. However, UCP2 expression in acute pancreatitis has not been previously reported. In the current experiments, pancreatic gene expression was studied by real-time reverse-transcription/p
Stem cells for cell therapy in Parkinson's disease.
A suggested Virtual Reality methodology allowing people with cognitive disabilities to communicate their knowledge and experiences of public transport systems
This paper presents a suggested methodology based on virtual reality (VR) technology that enables people with cognitive disabilities to communicate their knowledge and experiences of public transport systems. The users interacted with the VR system by verbally describing their actions to the person controlling the VR system and/or pointing with a laser pointer while seated in front of three screen
On the relation between A-codes and codes correcting independent errors
'Traceology' then and now
A review essay of two recent publications: L. Longo and N. Skakun (eds) "The Roots of Use-Wear Analysis: Selected Papers of S.A. Semenov" and "'Prehistoric Technology' 40 Years Later: Functional Studies and the Russian Legacy". These volumes were published upon the occasion of an international congress entitled 'Prehistoric Technology' 40 Years Later: Functional Studies and the Russian Legacy. The
Outcomes of reduced-intensity transplantation for chronic myeloid leukemia: an analysis of prognostic factors from the Chronic Leukemia Working Party of the EBMT
This study reports outcomes of allogeneic hematopoietic stem cell transplantation with reduced-intensity conditioning (RIC) in 186 patients with chronic myeloid leukemia (CML) from the European Group for Blood and Marrow Transplantation (EBMT). The median age was 50 years, and 64% were in first chronic phase (CP1), CP2 13%, accelerated phase 17%, and blast crises 6%. The median EBMT transplant sco
Convex bodies instead of needles in Buffon's experiment
An arbitrary fixed convex set in ${\bf R}^2$ is considered as are two families of equally spaced parallel lines making angle $\alpha$ with each other. It is assumed that the inter-line distance in each family of parallel lines is greater than the maximum width of the convex set. A congruent copy of the convex set is placed randomly (centroid uniform in one particular parallelogram cell and orienta
Methodological issues in the epidemiological study of the teratogenicity of drugs.
Regulation of the Notch target gene Hes-1 by TGFalpha induced Ras/MAPK signaling in human neuroblastoma cells.
Ras and Notch signaling have recently been shown to cooperate in the maintenance of neoplastic transformation. Here, we show that TGF alpha, a known activator of Ras signaling, can drive cell proliferation and at the same time induce the expression of the Notch target Hes-1 in the neuroblastoma cell line SK-N-BE(2)c. The up-regulation of Hes-1 occurred both at the transcriptional and protein level
The relationship between O-chain expression and colonisation ability of Helicobacter pylori in a mouse model
The influence of lipopolysaccharide (LPS) O-polysaccharide chain production on the colonisation ability of Helicobacter pylori in four mouse models (NMRI, C57BL/6, CBA/Ca, and BALB/cA mice) was studied. H. pylori strains that produced smooth-form LPS (S-LPS) detectable in silver-stained electrophoretic gels colonised mice. In contrast, a laboratory-passaged strain G50 and the culture collection st
Versican interacts with fibrillin-1 and links extracellular microfibrils to other connective tissue networks
Fibrillin-containing microfibrils are polymeric structures that are difficult to extract from connective tissues. Proteolytic digestion of tissues has been utilized to release microfibrils for study. Few of the molecules that connect microfibrils to other elements in the matrix have been identified. In this study, electron microscopic immunolocalization of anti-versican antibodies in tissues and i
