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A numerical study of mixing phenomena and reaction front propagation in partially premixed combustion engines

Avhandlingsarbetet studerar hur turbulent flödesstruktur sammverkar med förbränning av högoktaniga bränslen i partiellt förblandade förhållanden genom numeriska tredimensionella flödessimuleringar. Förbränningsmoder och antändningsprocesser studeras för två olika typfall där ett flertal metoder testas med ändamålet att korrekt återge hur icke upplöst rörelsemängd växelverkar med de kemiska processThis work treats the modelling of PPC engine combustion through 3D computational fluid dynamics. In order to develop a cost-effective CFD model for the design and performance analysis of PPC engines it is important to first understand the multiple modes of combustion in PPC engines, e.g., the onset of the first ignition kernels, the propagation of the ignition/flame fronts, and the effect of charg

Living degrowth? Investigating degrowth practices through performative methods

Degrowth scholarship argues for multi-scalar transformations beyond the growth-oriented economic paradigm to achieve long-term socio-ecological sustainability. While the literature on degrowth has grown substantially, little has been said about how these transformations are understood in practice. By drawing upon practice theory and using performative methods, this paper explores the ways in which

Changing diagnostic criteria for gestational diabetes in Sweden - A stepped wedge national cluster randomised controlled trial - The CDC4G study protocol

Background: The optimal criteria to diagnose gestational diabetes mellitus (GDM) remain contested. The Swedish National Board of Health introduced the 2013 WHO criteria in 2015 as a recommendation for initiation of treatment for hyperglycaemia during pregnancy. With variation in GDM screening and diagnostic practice across the country, it was agreed that the shift to new guidelines should be in a

The β2-Adrenergic Receptor Is a Molecular Switch for Neuroendocrine Transdifferentiation of Prostate Cancer Cells

The incidence of treatment-related neuroendocrine prostate cancer (t-NEPC) is rising as more potent drugs targeting the androgen signaling axis are clinically implemented. Neuroendocrine transdifferentiation (NEtD), an putative initial step in t-NEPC development, is induced by androgen-deprivation therapy (ADT) or anti-androgens, and by activation of the β2-adrenergic receptor (ADRB2) in prostate

Assembly and analysis of the genome sequence of the yeast Brettanomyces naardenensis CBS 7540

Brettanomyces naardenensis is a spoilage yeast with potential for biotechnological applications for production of innovative beverages with low alcohol content and high attenuation degree. Here, we present the first annotated genome of B. naardenensis CBS 7540. The genome of B. naardenensis CBS 7540 was assembled into 76 contigs, totaling 11,283,072 nucleotides. In total, 5168 protein-coding seque

The Role of Hypothalamic Pathology for Non-Motor Features of Huntington's Disease

Huntington's disease (HD) is a fatal genetic neurodegenerative disorder. It has mainly been considered a movement disorder with cognitive symptoms and these features have been associated with pathology of the striatum and cerebral cortex. Importantly, individuals with the mutant huntingtin gene suffer from a spectrum of non-motor features often decades before the motor disorder manifests. These sy

The impact of grade inflation on higher education enrolment and earnings

This study examines the consequences of grade inflation at the upper secondary education level on enrolment in higher education and earnings for Sweden. Although grade inflation is unfair and may imply inefficient allocation of human resources, current knowledge of grade inflation effects on individual outcomes is scarce. One explanation is probably the challenge of measuring and estimating causal

Choice Blindness, Confabulatory Introspection, and Obsessive–Compulsive Symptoms : Investigation in a Clinical Sample

The content of obsessions in obsessive–compulsive disorder (OCD) often run contrary to the actual self of the individual experiencing them. The ego-dystonic nature of obsessions has led some researchers to propose that individuals with OCD form these false beliefs about themselves due to limited introspective access. The current study therefore aimed to extend on recent findings from non-clinical

The sirius passet lagerstätte of north greenland : A remote window on the cambrian explosion

The lower Cambrian Lagerstätte of Sirius Passet, Peary Land, North Greenland, is one of the oldest of the Phanerozoic exceptionally preserved biotas. The Lagerstätte evidences the escalation of numbers of new body plans and life modes that formed the basis for a modern, functionally tiered ecosystem. The fauna is dominated by predators, infaunal, benthic and pelagic, and the presence of abundant n

Numerical studies of flame extinction and re-ignition behaviors in a novel, ultra-lean, non-premixed model GT burner using LES-ESF method

The flame dynamics in a novel, ultra-lean non-premixed model gas turbine (GT) burner flame was numerically studied using large eddy simulation (LES) coupled with probability density function (PDF) based on the Euler stochastic field (ESF) method. One non-reacting case and three reacting cases with global equivalence ratio ϕglob=1.0,0.6,0.3 were simulated. Comparison of mean flow fields and OH dist

The Forgotten Joint Score-12 in Swedish patients undergoing knee arthroplasty : a validation study with the Knee Injury and Osteoarthritis Outcome Score (KOOS) as comparator

Background and purpose — Having patients self-evaluate the outcome is an important part of the follow-up after knee arthroplasty. The Forgotten Joint Score-12 (FJS-12) introduced joint awareness as a new approach, suggested to be sensitive enough to differentiate well-functioning patients. This study evaluated the Swedish translation of the FJS-12 and investigated the validity, reliability, and in

Tailoring Radionuclide Therapy of Neuroendocrine Tumors - Bridging the Gaps

Background and Aims: Radionuclide therapy is systemic, targeted radiotherapy. As such, we can apply the basic principles of radiobiology used in everyday practice in radiation oncology, as a means of tailoring the treatment to each patient and optimizing the balance between efficacy and toxicity. The most common type of radionuclide therapy used for the treatment of neuroendocrine tumors, is 177Lu

Managing conflicting desires in a garden plant; the case of the variegated daylily

A gardener in Småland, southeastern Sweden, tells that her father cultivated a double daylily, Hemerocallis fulva, with variegated leaves in Stockholm in the mid 20th century. When she moved to Småland, 45 years ago, she brought a piece of his plant with her, and later on she has spread the plant to others. This daylily, known as "Kwanso Variegata", was first found in Japan in 1776, and since then

Why does sulfite reductase employ siroheme?

Sulfite reductase (SiR) contains in the active site a unique assembly of siroheme and a [4Fe4S] cluster, linked by a cysteine residue. Siroheme is a doubly reduced variant of heme that is not used for a catalytic function in any other enzyme. We have used non-equilibrium Green's function methods coupled with density functional theory computations to explain why SiR employs siroheme rather than hem

The Power of The Good Example: The Packaging of Characters and Places in Contemporary Nordic Noir

The recent global success story of Nordic noir, that encompasses products from film and television as well as literature, is often attributed to the great popularity of its places and characters. Many of the protagonists of some of the most popular TV-shows, for instance, are described as more in depth-characters than many of their European and American counterparts. Notable examples are Kurt Wall

Effect of fermentation and dry roasting on the nutritional quality and sensory attributes of quinoa

Background: Quinoa is a pseudocereal with relatively high content of proteins and minerals that also contains mineral inhibitors such as phytate. The aim of the present study was to evaluate lactic acid fermentation and dry roasting on the nutritional quality and sensory attributes of quinoa. Various processes were evaluated, and quinoa grains were dry-roasted, milled, and fermented, either with o

The abnormal heat transfer behavior of supercritical n-decane flowing in a horizontal tube under regenerative cooling for scramjet engines

This paper aims to describe the reasons why abnormal heat transfer occurs under the condition of regenerative cooling applied in scramjet engines. Supercritical n-decane flowing in a horizontal tube under various mass flow rates (G = 0.001, 0.002, 0.003, 0.004 kg/s) and heat fluxes (qw = 100, 200, 300, 400 kW/m2) is investigated by numerical simulations. The mechanisms of the abnormal heat transfe

Interpreters in healthcare : Nursing perspectives

PURPOSE: This study explored nursing experiences using interpreters in primary healthcare settings. METHODS: Eight nurses in southern Sweden were subjected to semistructured interviews. The responses were divided into three categories using content analysis: interpreter influence, challenges, and strategies. RESULTS: Despite using an interpreter to minimize language barriers, nurses do not achieve

Physiotherapist-led treatment for young to middle-aged active adults with hip-related pain : Consensus recommendations from the International Hip-related Pain Research Network, Zurich 2018

The 1st International Hip-related Pain Research Network meeting discussed four prioritised themes concerning hip-related pain in young to middle-aged adults: (1) diagnosis and classification of hip-related pain; (2) patient-reported outcome measures for hip-related pain; (3) measurement of physical capacity for hip-related pain; (4) physiotherapist-led treatment for hip-related pain. Thirty-eight