X-linked lymphoproliferative disease (XLP) is a rare and severe immune deficiency, characterized by abnormal immune responses to the Epstein-Barr virus. Recently, the gene responsible for XLP, SH2D1A, has been identified and shown to code for a small cytoplasmic protein with an SH2 domain that interacts with SLAM and 2B4, two receptorial molecules involved in signal transduction in T and NK cells,

Attachment of microorganisms to host cells is believed to be a critical early step in microbial pathogenesis. The aim of the study was to determine the role of the known glycosaminoglycan (GAG) binding activity of Staphylococcus aureus and coagulase-negative staphylococci (CoNS) in their attachment to six different eukaryotic cell lines. Three staphylococcal species expressing GAG binding capacity

Aims: The increasing number of people on disability pension in Sweden is of concern for Swedish policy-makers, and there is a need for a better understanding of the mechanisms behind disability pension. We investigated ( i) whether women living in the same neighborhood have a similar propensity for disability pension that relates to neighborhood social participation, and ( ii) whether there is an

We summarize the activities of Working Group 2 of the HERA/LHC Workshop dealing with multi-jet final states and energy flows. Among the more specific topics considered were underlying event and minimum bias, rapidity gaps and survival probabilities, multi-jet topologies and multi-scale QCD, and parton shower–matrix element matching.

The purpose was to investigate, in a sample of drug abusers, whether subscales in the KAPP (Karolinska Psychodynamic Profile, Weinryb, 1992) interview and defense mechanisms explored by the DMTm (Defense Mechanism Technique modified) could differentiate between DSM-III-R clusters and personality disorders (PDs). Forty-seven (47) subjects out of the 84 injecting drug abusers (56%) recruited from a

Volatile organic compounds (VOC) cause odour problems and constitute a significant part of the chemical oxygen demand (COD) emissions from the kraft mill. Most of these are found in the cooking and evaporation condensates. The design of efficient methods for the removal of the VOC requires knowledge of the vapour-liquid (VLE) and liquid-liquid equilibrium (LLE). In the present study VLE for the mo

Popular Abstract in Swedish Statlig intervention i ekonomin har, med varierande form och intensitet, varit ett allestädes närvarande fenomen i historien som haft genomgripande betydelse för handel, välfärd, internationella relationer och politiskt och ekonomiskt tänkande. Denna avhandling ger en omfattande analys av politiska ingrepp i den europeiska bilindustrin. Den skildrar politikens utvecklinState policy intervention in the economy has been a ubiquitous phenomenon in history. Varying in form and intensity, it has had a profound impact on trade, welfare, international relations, and political and economic thinking. This thesis provides an inclusive analysis of policy action in the European car industry. It details its development, processes, nature, and content and presents the story a

Nils Månsson Mandelgren levde mellan 1813-1899. Han skaffade sig en konstnärlig utbildning på konstakademierna i Stockholm och Köpenhamn. Genomförde flera forskningsresor i Sverige och dokumenterade allmogekultur, fornminnen samt kyrklig och profan konst och arkitektur. Han deltog bland annat i grundandet av nuvarande Konstfack 1844 och Svensk form året därpå. Mandelgrens forskningsmaterial förvar

Portland cement clinkers from two production units were investigated; Plant 1: ordinary clinker (P1) and clinker mineralised with CaF2+CaSO4 (P1m); Plant 2: ordinary clinker (P2) and two clinkers mineralised with CaF2+CaSO4 (P2m, low SO3 and P2m', high SO3). The chemical composition of the clinkers was determined by X-ray fluorescence, ICP analysis, titration (free lime) and ion selective electrod

The aim of this study was to establish tolerable fire risk criteria for hospitals. The event tree technique was used to assess the safety level in a model hospital building. Risk profiles were derived and tolerable criteria established by evaluating the risk. The motivation behind this methodology is that buildings designed completely in accordance with today’s regulations must be considered safe

Stadens påverkan på vattenmiljön diskuteras utifrån ett avrinningsområdesperspektiv med i huvudsak Höje å som tillämpningsexempel. Staden påverkar tungmetall- och fosforkoncentrationer i avrinnande åar om staden motsvarar ungefär 100 000 personer i ett 300 km2 stort vrinningsområde.The influence of the city on the water environment on river basin scale is discussed with mainly the Höje River as an example. The city significantly influence the phosphorous and heavy metal conditions if the city is larger than about 100 000 people in an agricultural river basin smaller than 300 km2.

The phase behavior of dilute mixtures of dioleoylphosphatidylethanolamine (DOPE) and reduced TritonX100 (TX100(r)) has been investigated at pH 7.4 and 10. Using simple turbidity measurements and optical observations, together with cryo-transmission electron microscopy (cryo-TEM), we estimate the phase boundaries. We show that at both pH 7.4 and 10, a very large amount of surfactant is needed for t

Popular Abstract in Swedish Avhandlingen behandlar det nytestamentliga Judasbrevets texthistoria. Monografin inleds med en översikt av textforskningen på de Katolska Breven i allmänhet och Judasbrevet i synnerhet, från 1800-talet och fram till nutid. Mot bakgrund av det tecknade forskningsläget beskriver så författaren studiens upplägg och syfte, samt antyder några av resultaten. Det handlar främsThis study treats the textual tradition of the Epistle of Jude. After an introductory survey of earlier text-critical research, the two main purposes of this investigation are formulated: to gather and to analyze the complete textual evidence of the Epistle of Jude. The first task, to gather the evidence, involves the collation of all Greek continuous text MSS of the Epistle of Jude. The evidence

Magnesium chelatase inserts Mg2+ into protoporphyrin IX and is the first unique enzyme of the chlorophyll biosynthetic pathway. It is a heterotrimeric enzyme, composed of I- (40 kDa), D- (70 kDa) and H- (140 kDa) subunits. The I- and D-proteins belong to the family of AAA(+) (ATPases associated with various cellular activities), but only I-subunit hydrolyses ATP to ADP. The D-subunits provide a pl

Aims: This cohort study on urban middle-aged men investigates the association between the use of analgesics and hypnotics, self-rated health (SRI-I) and disability pension. Methods: Five birth-year cohorts of middle-aged, urban, Swedish men were invited to a screening programme and were followed for approximately 11 years. Results: Out of all the subjects (n = 5798), 12.4% received a disability pe

Pollen records from 21 sites were used to reconstruct Holocene hydrological changes in northern Fennoscandia. The inferred dominance of maritime-type Betula-forests from c. 9600 BP onwards indicate an oceanic climate in the region during the early Holocene, with high amounts of precipitation and low seasonal contrasts. This interpretation is supported by oxygen isotope records obtained on lacustri