Background: Contemporary patients with pulmonary arterial hypertension (PAH) are older and exhibit cardiovascular or/and lung comorbidities. Such patients have typically been excluded from major PAH drug trials. This systematic review compares baseline characteristics, hemodynamic parameters, and mortality rate between PAH patients with significant number of comorbidities compared to those with fe

With more than 260 000 islands, Sweden is one of the countries with most islands in the world. Its islands are located along the coasts and in the larger lakes. For the municipalities and regions where they are located, the islands are places for recreation and symbols in tourism marketing. A rough overview over the impact of the pandemic on rural and remote areas indicates that Swedish tourism in

A recent rise in climate-related risks, encompassing floods, landslides, storms, and heat waves, has been noted across Sweden, resulting in significant property damage amounting to millions of Euros. While contemporary homes are being developed with climate-resilient designs, the existing housing stock remains exposed to the dynamic challenges of climate hazards. The primary research objective is

The majority of single-family houses in Sweden are affected by deteriorations in building envelopes as well as heating, ventilation and air conditioning systems, since they are about 30 years old. Theses house are therefore in need of extensive renovation, which provides an excellent opportunity to incorporate energy efficiency measures to reduce both the energy consumption and also operational. A

To investigate multimodal signals in cat–human communication we recorded 36 cat–owner interactions in everyday situations that were judged by the owners for valence (negative, mixed or positive). We then coded the videos for behaviour using an ethogram including vocal, visual and tactile (multimodal) signals. Vocalisations were segmented and acoustic measures of duration and F0 obtained. In cats,

Plasma proteomics offers high potential for biomarker discovery, as plasma is collected through a minimally invasive procedure and constitutes the most complex human-derived proteome. However, the wide dynamic range poses a significant challenge. Here, we propose a semi-automated method based on the use of multiple single chain variable fragment antibodies, each enriching for peptides found in up

This thesis addresses the critical issue of design and development of products like production machines for SMEs and rural communities as an essential capability to foster local technology development within the innovation systems of Latin America. What is studied and discussed in this thesis is the pre-requisites for effective application of design and development methods, like design thinking fo

Air pollution is a global health problem and in Mozambique, indoor air pollution is primarily causedby cooking over an open fire. This study examines the potential of coconut charcoal as a cleanercooking fuel and as a possible source of income for women in the village of Linga Linga, Mozambique.Previous research conducted in the village identified a need to investigate the willingness of thecommunAir pollution is a global health problem and in Mozambique, indoor air pollution is primarily caused by cooking over an open fire. This study examines the potential of coconut charcoal as a cleaner cooking fuel and as a possible source of income for women in the village of Linga Linga, Mozambique. Previous research conducted in the village identified a need to investigate the willingness of the co

Energy economists have long argued that energy systems need to be adaptable in the face of shocks. In the early twentieth century, Denmark embodied the opposite, with its industry almost entirely dependent on imports of coal from the UK. Towards the end of the First World War, however, and well into the 1920s, coal imports became expensive and more difficult to obtain. Local diversification was po

This paper compares general measures against tax avoidance and the design of general anti-avoidance rules (GAARs) in Denmark, Finland, Norway, and Sweden. It focuses on aspects such as tax benefits, tax purposes, economic substance, and breaches of legislative purpose. The paper also examines potential compliance issues between national GAARs, tax treaties, and the European Union’s Anti-Tax Avoida

BACKGROUND: Discrimination may further impede access to medical care for individuals in socially disadvantaged positions. Sociodemographic information and perceived discrimination intersect and define multiple contexts or strata that condition the risk of refraining from seeking physician's care. By applying analysis of individual heterogeneity and discriminatory accuracy (AIHDA) we aimed to impro

A search for leptoquark pair production decaying into te-t¯e+ or tμ-t¯μ+ in final states with multiple leptons is presented. The search is based on a dataset of pp collisions at s=13TeV recorded with the ATLAS detector during Run 2 of the Large Hadron Collider, corresponding to an integrated luminosity of 139 fb-1. Four signal regions, with the requirement of at least three light leptons (electron

Bakgrund Långvarig behandling med opioida läkemedel, här definierat som> 3 månader, på indikation långvarig icke-malign smärta är vanligt förekommande i smärtvården. Vid undersökningar i Lund och Linköping har noterats att ungefär en tredjedel av populationen vid smärtklinikerna exponeras för opioidbehandling, trots avsaknad av evidens och samtidigt väl kända risker med behandlingen. Nedtrappning

We experimentally investigate the degree to which redistribution, the act of taking money from some individuals and giving it to others, affects social capital in groups. We measure social capital as the degree to which group members exhibit cooperativeness, trust and trustworthiness toward one another. Our experiment involves several rounds of real-effort production, in which we vary the degree t

Under rådande Covid-19 pandemi har lungan kommit i nytt fokus då vissa som insjuknar ser ut att få bestående förändringar på lungvävnaden. Förändringar som potentiellt kan utvecklas till lungfibros. I Gunilla Westergren-Thorssons forskargrupp inom lungbiologi vid Lunds universitet, arbetar ett 20-tal cellbiologer, kemister, ingenjörer och läkare med att i detalj studera lungvävnadens mikromiljö oc