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A gold mine, but still no Klondike: Nordic register data in health inequalities research

Published 15 October 2019 Future research on health inequality relies on data that cover life-course exposure, different birth cohorts and variation in policy contexts. Nordic register data have long been celebrated as a ‘gold mine’ for research, and fulfil many of these criteria. However, access to and use of such data are hampered by a number of hurdles and bottlenecks. New publication in Scandi

https://www.lupop.lu.se/article/gold-mine-still-no-klondike-nordic-register-data-health-inequalities-research - 2025-01-04

Network multipliers and public health

Published 16 October 2019 The term ‘spillover effect’ is sometimes used in the social and biomedical sciences to describe one person’s exposure affecting the outcome of another. The term ‘contagion’ is sometimes used to describe one person’s outcome affecting another’s outcome. One classic setting for such spillover and contagion is that of vaccines and infectious diseases. New publication in Inte

https://www.lupop.lu.se/article/network-multipliers-and-public-health - 2025-01-04

Stronger together — The power of combining existing registry data

Published 17 October 2019 Patients with psychiatric disorders have a significantly higher risk of cardiovascular disease and sudden cardiac arrest than the general population, and this study by Barcella et al. has demonstrated that patients with a psychiatric disorder were twice as likely to die as a result of out-of-hospital cardiac arrest (OHCA). New publication in Resuscitation.Read more here.

https://www.lupop.lu.se/article/stronger-together-power-combining-existing-registry-data - 2025-01-04

Estimation of Natural Indirect Effects Robust to Unmeasured Confounding and Mediator Measurement Error

Published 18 October 2019 The use of causal mediation analysis to evaluate the pathways by which an exposure affects an outcome is widespread in the social and biomedical sciences. Recent advances in this area have established formal conditions for identification and estimation of natural direct and indirect effects. However, these conditions typically involve stringent assumptions of no unmeasure

https://www.lupop.lu.se/article/estimation-natural-indirect-effects-robust-unmeasured-confounding-and-mediator-measurement-error - 2025-01-04

EpiDem Junior Conference - Call for papers

Published 22 October 2019 The EpiDem Network has been funded by FORTE (Swedish Research Council for Health, Working Life and Welfare) 2015, 2016 - 2018, and 2019-2021. The aim of this national network is to strengthen the position of Swedish register-based research, partly through increased knowledge and shared experiences regarding adequate scientific approaches and partly by forming new long-ter

https://www.lupop.lu.se/article/epidem-junior-conference-call-papers - 2025-01-04

The Third China National Stroke Registry (CNSR-III) for patients with acute ischaemic stroke or transient ischaemic attack: design, rationale and baseline patient characteristics

Published 24 October 2019 Stroke is the leading cause of mortality and disability in China. Precise aetiological classification, imaging and biological markers may predict the prognosis of stroke. The Third China National Stroke Registry (CNSR-III), a nationwide registry of ischaemic stroke or transient ischaemic attack (TIA) in China based on aetiology, imaging and biology markers, will be consid

https://www.lupop.lu.se/article/third-china-national-stroke-registry-cnsr-iii-patients-acute-ischaemic-stroke-or-transient-ischaemic - 2025-01-04

Survival Bias in Mendelian Randomization Studies A Threat to Causal Inference

Published 25 October 2019 It has been argued that survival bias may distort results in Mendelian randomization studies in older populations. Through simulations of a simple causal structure we investigate the degree to which instrumental variable (IV)-estimators may become biased in the context of exposures that affect survival. We observed that selecting on survival decreased instrument strength

https://www.lupop.lu.se/article/survival-bias-mendelian-randomization-studies-threat-causal-inference - 2025-01-04

Was it worth it? Older adults’ experiences of participating in a population-based cohort study – a focus group study

Published 28 October 2019 At present, we know relatively little about priorities and problems with topics that older adults experience when completing different examinations in longitudinal population-based studies. To examine these topics, research must be adapted to investigate the meanings, motivations, and interpretations of the individual participants themselves. New publication in BMC Geriat

https://www.lupop.lu.se/article/was-it-worth-it-older-adults-experiences-participating-population-based-cohort-study-focus-group - 2025-01-04

Cancer registries - guardians of breast cancer biomarker information: A systematic review

Published 30 October 2019 Breast cancer is the most common cancer and the leading cause of cancer-related death in females, with a large societal and economic impact. Decisions regarding its treatment are largely affected by the categorization into different subtypes with hormone receptor status and HER2 status being the most important predictive factors. New publication in SAGE Journals.Read more

https://www.lupop.lu.se/article/cancer-registries-guardians-breast-cancer-biomarker-information-systematic-review - 2025-01-04

Development and Implementation of a Wheelchair Outcomes Registry

Published 31 October 2019 The FMA is a validated 10-item patient-centered outcome measure that investigates satisfaction in performing common mobility-related activities of daily living. The UDS includes variables related to age, diagnosis, and type of device used, as well as health, participation, and environmental factors. New publication in Archives of Physical Medicine and Rehabilitation.Read

https://www.lupop.lu.se/article/development-and-implementation-wheelchair-outcomes-registry - 2025-01-04

The impact of parenthood on risk of registration for alcohol use disorder in married individuals: a Swedish population-based analysis

Published 1 November 2019 In married individuals, resident children are associated with a reduction in basal risk for AUD which is stronger in mothers than fathers and with younger v. older children. This effect is also evident during high-risk periods. In mothers, our results are consistent with a largely causal effect. New publication in Psychological Medicine.Read more here.

https://www.lupop.lu.se/article/impact-parenthood-risk-registration-alcohol-use-disorder-married-individuals-swedish-population - 2025-01-04

Research methodology and practical issues relating to the conduct of a medical device registry

Published 4 November 2019 Both clinical trials and registries are essential and complementary research methods and the strengths and weaknesses of each need to be recognized. The specific characteristics of registry research deserve to be acknowledged and safeguarded in the regulations governing clinical investigations with medical devices. New publication in SAGE Journals.Read more here

https://www.lupop.lu.se/article/research-methodology-and-practical-issues-relating-conduct-medical-device-registry - 2025-01-04

On the potential of incorporating administrative register data into randomized experiments

Published 5 November 2019 Employing Norwegian register data in a between-group comparison illustrates that register data would be particularly useful for several key areas of an RCT, including as a source of pilot data, to expand the range of variables on which between-group equivalence can be demonstrated, to increase the length of the observation period, to expand the number and type of individu

https://www.lupop.lu.se/article/potential-incorporating-administrative-register-data-randomized-experiments - 2025-01-04

National Cancer Database: The Past, Present, and Future of the Cancer Registry and Its Efforts to Improve the Quality of Cancer Care

Published 7 November 2019 The National Cancer Database (NCDB) continues to evolve to improve the care of the cancer patient. Over the last 30 years, the NCDB has compiled nearly 40 million patient records submitted by over 1500 hospitals across the country. Addressing new challenges, the NCDB is transitioning to ensure data flow is more timely and data collection more efficient. New publication in

https://www.lupop.lu.se/article/national-cancer-database-past-present-and-future-cancer-registry-and-its-efforts-improve-quality - 2025-01-04

Early-life inequalities and biological ageing: a multisystem Biological Health Score approach in Understanding Society

Published 8 November 2019 Social position is known to play a role in the quality of ageing, notably through the stimulation/dysregulation of key physiological systems in response to external stresses. Using data from one wave of Understanding Society including 9088 participants, we defined, as an extension of the allostatic load, a synthetic Biological Health Score (BHS) capturing the wear-and-tea

https://www.lupop.lu.se/article/early-life-inequalities-and-biological-ageing-multisystem-biological-health-score-approach - 2025-01-04