Search results

Directed acyclic graphs (DAGs) are popular tools for identifying appropriate adjustment strategies for epidemiological analysis. However, a lack of direction on how to build them is problematic. As a solution, we propose using a combination of evidence synthesis strategies and causal inference principles to integrate the DAG-building exercise within the review stages of research projects. We demon

https://www.lupop.lu.se/article/evidence-synthesis-constructing-directed-acyclic-graphs-esc-dags-novel-and-systematic-method - 2025-10-27

Exposures to perfluoroalkyl substances (PFAS) have shown positive associations with serum lipids in previous studies. While many studies on lipids investigated associations with perfluorooctane sulfonic acid (PFOS) and perfluorooctanoic acid (PFOA), there are only a few studies regarding other PFAS, such as perfluorohexane sulfonic acid (PFHxS). The purpose of the current study is to investigate i

https://www.lupop.lu.se/article/associations-between-perfluoroalkyl-substances-and-serum-lipids-swedish-adult-population - 2025-10-27

Partial exchangeability is sufficient for the identification of some causal effects of interest. Here we review the use of common graphical tools and the sufficient component cause model in the context of partial exchangeability. We illustrate the utility of single world intervention graphs (SWIGs) in depicting partial exchangeability and provide an illustrative example of when partial exchangeabi

https://www.lupop.lu.se/article/graphical-description-partial-exchangeability - 2025-10-27

For a significant proportion of the older population, increasing age is associated with health problems and worsening health. Older family caregivers are largely responsible for care of next-of-kin living at home, which impacts their own physical and mental health both positively and negatively. However, evidence is insufficient regarding the health situation of older caregivers. The aim of this s

https://www.lupop.lu.se/article/analyzing-situation-older-family-caregivers-focus-health-related-quality-life-and-pain-cross - 2025-10-27

Analyses of causal mediation are often complicated by treatment-induced confounders of the mediator–outcome relationship. In the presence of such confounders, the natural direct and indirect effects of treatment on the outcome, into which the total effect can be additively decomposed, are not identified. An alternative but similar set of effects, known as randomized intervention analogues to the n

https://www.lupop.lu.se/article/effect-decomposition-presence-treatment-induced-confounding-regression-residuals-approach - 2025-10-27

Heparin is the preferred choice of anticoagulant in percutaneous coronary intervention (PCI) for acute myocardial infarction (MI). An established dosage of heparin has not yet been determined, but treatment may be optimized through monitoring of activated clotting time (ACT).. New publication in Europe PMC

https://www.lupop.lu.se/article/relationship-between-degree-heparin-anticoagulation-and-clinical-outcome-patients-receiving-potent - 2025-10-27

This issue of the Journal contains two articles focusing on how to draw causal conclusions using data from multiple studies that would generally be analyzed via meta-analysis. New publication in Epidemiology.

https://www.lupop.lu.se/article/importance-homogeneous-effect-modification-causal-interpretation-meta-analyses - 2025-10-27

In this population-based study, we compared the incidence of distal radius fracture in 2016 with that in the same region’s adult general population in 2001 using radiographs to identify fracture cases. We showed that the incidence decreased by 24% in 2016 compared with 2001 indicating an important development. New publication in Osteoporosis International

https://www.lupop.lu.se/article/incidence-distal-radius-fracture-general-population-southern-sweden-2016-compared-2001 - 2025-10-27

We recently suggested new statistical metrics for routine reporting in random-effects meta-analyses to convey evidence strength for scientifically meaningful effects under effect heterogeneity. First, given a chosen threshold of meaningful effect size, we suggested reporting the estimated proportion of true population effect sizes above this threshold. Second, we suggested reporting the proportion

https://www.lupop.lu.se/article/robust-metrics-and-sensitivity-analyses-meta-analyses-heterogeneous-effects - 2025-10-27

In this prospectively registered cohort study, we analyzed clinical, pathological, and survival outcomes for patients operated in the period 2008–2015 and compared the two strategies. New publication in World Journal of Surgery

https://www.lupop.lu.se/article/outcomes-simultaneous-resections-and-classical-strategy-synchronous-colorectal-liver-metastases - 2025-10-27

We take steps toward causally interpretable meta-analysis by describing methods for transporting causal inferences from a collection of randomized trials to a new target population, one trial at a time and pooling all trials. We discuss identifiability conditions for average treatment effects in the target population and provide identification results. We show that the assumptions that allow infer

https://www.lupop.lu.se/article/toward-causally-interpretable-meta-analysis-transporting-inferences-multiple-randomized-trials-new - 2025-10-27

Innehåll: DORIS redo för lansering i maj, befolkningsforskning en utmaning när data ska göras tillgängliga, SND lanserar nya webbsidor om datahantering för forskare, RDA-Sweden anordnar workshop om datahanteringsplaner Läs mer här.

https://www.lupop.lu.se/article/natverks-nytt-fran-snd - 2025-10-27

A webinar arranged by Athena Research Center (ARC), in the context of OpenAIRE Greek National Open Access Desk, the Research Data Alliance (RDA) Greek Node and ELIXIR-GR activities. Read more at https://www.rd-alliance.org/blogs/greek-bottom-initiative-collaborate-a….

https://www.lupop.lu.se/article/greek-bottom-initiative-collaborate-and-support-covid-19-research - 2025-10-27

Science is one of the greatest collective endeavors and the most important channel for gaining knowledge. Scientific research is the collecting of data to investigate and explain a phenomenon or theory with the help of the scientific process. The idea of science is that you can only learn about a phenomenon reliably and accurately by collecting empirical data. What role does science and research p

https://www.lupop.lu.se/article/fair-maturity-evaluation-nordic-and-baltic-data-repositories - 2025-10-27

The post-doctoral position involves working on epidemiological studies of obesity and metabolic factors in relation to the risk and survival of prostate cancer investigated in a large database of several Swedish cohorts and national registers. The studies will be deeply oriented in statistical and epidemiological methods. Read more here.

https://www.lupop.lu.se/article/post-doctoral-position-cancer-epidemiology - 2025-10-27

The European Commission has awarded a contract for the setting up of an open access publishing platform for scientific articles as a free service for Horizon 2020 beneficiaries. The launch of the ambitious EU open access initiative is planned for early 2021. Read more at https://ec.europa.eu/info/news/european-commission-awards-contract-sett….

https://www.lupop.lu.se/article/open-access-publishing-platform-horizon-2020 - 2025-10-27

Looking to apply for the Knut & Alice Wallenberg (KAW) annual project grant? Welcome to sign up to an information meeting hosted by Research Services in collaboration with the Faculty of Engineering, the Faculty of Medicine and the Faculty of Science. Read more at https://fs.blogg.lu.se/information-meeting-project-applications-to-the-….

https://www.lupop.lu.se/article/information-meeting-knut-and-alice-wallenberg-foundation - 2025-10-27

Meta-analysis is widely used to combine the findings of multiple disparate studies of health risks or treatment response. Meta-analysis often uses a random-effects model to express heterogeneity across studies. The model interprets a weighted average of study-specific estimates as an estimate of a mean parameter across a hypothetical population of studies. New publication in Epidemiology

https://www.lupop.lu.se/article/toward-credible-patient-centered-meta-analysis - 2025-10-27

In occupational therapy, while several studies have focussed on occupational balance, few have investigated it in the context of sleep. The aim of this study was to investigate the associations between sleep and occupational balance among women. New publication in Scandinavian Journal of Occupational Therapy

https://www.lupop.lu.se/article/occupational-balance-and-sleep-among-women - 2025-10-27

Various questionnaire-based definitions of chronic obstructive pulmonary disease (COPD) have been applied using the US representative National Health and Nutrition Examination Survey (NHANES), but few have been validated against objective lung function data. We validated two prior definitions that incorporated self-reported physician diagnosis, respiratory symptoms, and/or smoking. We also validat

https://www.lupop.lu.se/article/validation-questionnaire-based-case-definitions-chronic-obstructive-pulmonary-disease - 2025-10-27