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From molecule to patient – Six promising projects to advance Parkinson's research

By martina [dot] svensson [at] med [dot] lu [dot] se (Martina Svensson) - published 2 April 2025 Photo: Emma Nyberg. What role does an inflammatory protein have in disease development? Which neuronal circuits cause different symptoms? How may diabetes affect Parkinson’s disease? Can motor signs be identifies early in individuals at risk for the disease? And how should patients in very advanced dis

https://www.multipark.lu.se/article/molecule-patient-six-promising-projects-advance-parkinsons-research - 2025-04-21

A new reliable blood marker reveals the extent of Alzheimer’s pathology in the brain

By tove [dot] smeds [at] med [dot] lu [dot] se (Tove Smeds) - published 14 April 2025 Professor Oskar Hansson, professor in neurology at Lund University. Photo: Tove Smeds Researchers at Lund University and Washington University have identified a blood marker that reflects the amount of Alzheimer’s pathology in the brain. This discovery may play a key role in determining who is most likely to bene

https://www.multipark.lu.se/article/new-reliable-blood-marker-reveals-extent-alzheimers-pathology-brain - 2025-04-21

More opportunities to test for Alzheimer’s using new analytical method

By tove [dot] smeds [at] med [dot] lu [dot] se (Tove Smeds) - published 15 April 2025 “Even with the simpler method of analysis, the blood test gives highly accurate results for Alzheimer’s disease pathology,” says Sebastian Palmqvist, associate professor and senior lecturer in neurology at Lund University. Photo: iStock A simpler method of analysing blood samples for Alzheimer’s disease has been

https://www.multipark.lu.se/article/more-opportunities-test-alzheimers-using-new-analytical-method - 2025-04-21

The unexpected way we might one day diagnose Alzheimer’s

Published 3 April 2019 How do you stop Alzheimer’s disease without a simple way to diagnose it? It’s a real chicken and egg problem, as I wrote last year on TGN. Discovering a treatment for Alzheimer’s requires lots of clinical trials for new drugs—but it’s difficult to enroll participants without a way to identify people who have the disease early enough for potential treatments to work. Read the

https://www.multipark.lu.se/article/unexpected-way-we-might-one-day-diagnose-alzheimers - 2025-04-21

More evidence that blood tests can detect the risk of Alzheimer’s

Published 23 April 2019 A new study confirms that a simple blood test can reveal whether there is accelerating nerve cell damage in the brain. The researchers analysed neurofilament light protein (NFL) in blood samples from patients with Alzheimer’s disease. Recently published in JAMA Neurology, the study suggests that the NFL concentration in the blood could be able to indicate if a drug actually

https://www.multipark.lu.se/article/more-evidence-blood-tests-can-detect-risk-alzheimers - 2025-04-21

Researchers block protein that plays a key role in Alzheimer’s disease

Published 21 May 2019 In recent years, it has become increasingly clear to researchers that the protein galectin-3 is involved in inflammatory diseases in the brain. A study led by researchers at Lund University in Sweden now shows the de facto key role played by the protein in Alzheimer’s disease. When the researchers shut off the gene that produces this protein in mice, the amount of Alzheimer’s

https://www.multipark.lu.se/article/researchers-block-protein-plays-key-role-alzheimers-disease - 2025-04-21

Minerva award to Tomas Deierborg

Published 10 June 2019 The Future Faculty is proud to present the 2019 Minerva Award to Tomas Deierborg, associate professor at the Department of Experimental Medical Sciences.The Minerva award selection committee's motivation for the choice is: "The core values of the Minerva award are honesty, trust, fairness, respect, responsibility and courage. From the nominations it is obvious that Tomas Dei

https://www.multipark.lu.se/article/minerva-award-tomas-deierborg - 2025-04-21

Drawing Closer: Alzheimer’s Blood Test for Primary Care

Published 25 June 2019 In today’s JAMA Neurology, researchers led by Oskar Hansson, Lund University, Sweden, report how a fully automated immunoassay for plasma Aβ performed when they put it through its paces. Roche Diagnostic’s Elecsys system predicted Aβ-positive individuals with about 80 percent accuracy. That number improved by 5 percent when the researchers took ApoE genotype into considerati

https://www.multipark.lu.se/article/drawing-closer-alzheimers-blood-test-primary-care - 2025-04-21

New PET Staging Scheme for Amyloid?

Published 6 August 2019 Scientists are becoming more nuanced in how they use amyloid scans—not just to detect the presence of Alzheimer’s pathology, but also to pinpoint disease stage. At this year’s Alzheimer’s Association International Conference, held July 13–18 in Los Angeles, researchers led by Niklas Mattsson and Oskar Hansson at Lund University, Sweden, debuted a new staging scheme. Read th

https://www.multipark.lu.se/article/new-pet-staging-scheme-amyloid - 2025-04-21

Parkinson Skåne visits BMC

Published 4 November 2019 Event organizers: Kajsa Brolin (representing Maria Swanberg), Gerard Müller (ParkinsonSkåne chair), Angela Cenci Nilsson, Georg Stenberg (lecturer and person with Parkinson), Andreas Heuer On October 30, MultiPark arranged, in collaboration with the Parkinson Skåne patient organization and Studieförbundet Vuxenskolan, a half-day study visit for the public to the Biomedica

https://www.multipark.lu.se/article/parkinson-skane-visits-bmc - 2025-04-21

Skiers had lower incidence of depression and vascular dementia – but not Alzheimer’s

Published 26 November 2019 Half as many diagnosed with depression, a delayed manifestation of Parkinson’s, a reduced risk of developing vascular dementia - but not Alzheimer’s. These connections were discovered by researchers when they compared 200 000 people who had participated in a long-distance cross-country ski race between 1989 and 2010 with a matched cohort of the general population. The re

https://www.multipark.lu.se/article/skiers-had-lower-incidence-depression-and-vascular-dementia-not-alzheimers - 2025-04-21

High-tech method for uniquely targeted gene therapy developed

Published 13 December 2019 Neuroscientists at Lund University in Sweden have developed a new technology that engineers the shell of a virus to deliver gene therapy to the exact cell type in the body that needs to be treated. The researchers believe that the new technology can be likened to dramatically accelerating evolution from millions of years to weeks.Read the full article here

https://www.multipark.lu.se/article/high-tech-method-uniquely-targeted-gene-therapy-developed - 2025-04-21

New imaging method sheds light on Alzheimer's disease

Published 1 April 2020 To understand what happens in the brain when Alzheimer's disease develops, researchers need to be able to study the molecular structures in the neurons affected by Alzheimer's disease. Researchers at Lund University in Sweden have tested a new imaging method for this purpose. The research is published in the journal Advanced Science.Read the full article here

https://www.multipark.lu.se/article/new-imaging-method-sheds-light-alzheimers-disease - 2025-04-21

New method provides unique insight into the development of the human brain

Published 26 May 2020 Stem cell researchers at Lund University in Sweden have developed a new research model of the early embryonic brain. The aim of the model is to study the very earliest stages of brain to understand how different regions in the brain are formed during embryonic development. With this new insight, researchers hope to be able to produce different types of neural cells for the tr

https://www.multipark.lu.se/article/new-method-provides-unique-insight-development-human-brain - 2025-04-21

How toxic protein spreads in Alzheimer’s disease

Published 1 June 2020 Toxic versions of the protein tau are believed to cause death of neurons of the brain in Alzheimer’s disease. A new study published in Nature Communications shows that the spread of toxic tau in the human brain in elderly individuals may occur via connected neurons. The researchers could see that beta-amyloid facilitates the spread of toxic tau.Read the full article here

https://www.multipark.lu.se/article/how-toxic-protein-spreads-alzheimers-disease - 2025-04-21

Message from the coordinator

Published 18 June 2020 From the coordinator:As we approach Midsommar, we in MultiPark can reflect on the extraordinary last few months and hope that our environment can return back more to meetings, seminars and productive exchanges after the summer. Although neurodegenerative diseases were less in the news because of Covid-19, people with Parkinson and Alzheimer’s diseases were however more affec

https://www.multipark.lu.se/article/message-coordinator - 2025-04-21