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Consumption of red meat, genetic susceptibility, and risk of LADA and type 2 diabetes

Published 28 July 2020 Analyses were based on Swedish case–control data comprising incident cases of LADA (n = 465) and T2D (n = 1528) with matched, population-based controls (n = 1789; n = 1553 in genetic analyses). Multivariable-adjusted ORs in relation to self-reported processed and unprocessed red meat intake were estimated by conditional logistic regression models. Attributable proportion (AP

https://www.lupop.lu.se/article/consumption-red-meat-genetic-susceptibility-and-risk-lada-and-type-2-diabetes - 2025-02-07

Familial risk of breast cancer by dynamic, accumulative, and static definitions of family history

Published 29 July 2020 The authors assessed the effect of incorporating the timing of cancer diagnosis events into the assessment of familial risks of breast cancer in first‐degree and second‐degree relatives in a nationwide cohort study of 5,099,172 women (follow‐up was between 1958‐2015). Family history was assessed using 3 approaches: 1) as a static variable (ever having a relative with breast

https://www.lupop.lu.se/article/familial-risk-breast-cancer-dynamic-accumulative-and-static-definitions-family-history - 2025-02-07

Ulnar Nerve Entrapment in Diabetes: Patient-reported Outcome after Surgery in National Quality Registries.

Published 29 July 2020 Ulnar nerve entrapment at the elbow (UNE) is overrepresented in patients with diabetes, but the outcome of surgery is unknown. We aimed to evaluate patient-reported outcome in patients with and without diabetes, and to assess potential sex differences and compare surgical treatment methods. Data on patients operated for UNE (2010-2016, n = 1354) from the Swedish National Reg

https://www.lupop.lu.se/article/ulnar-nerve-entrapment-diabetes-patient-reported-outcome-after-surgery-national-quality-registries - 2025-02-07

RDA COVID-19 Recommendations and Guidelines for Data Sharing

Published 30 July 2020 The recommendations in the document are aimed at helping policymakers and funders to maximise timely, quality data sharing and appropriate responses in future health emergencies. The Research Data Alliance (RDA) COVID-19 Working Group members bring various, global expertise to develop a body of work that comprises how data from multiple disciplines inform response to a pande

https://www.lupop.lu.se/article/rda-covid-19-recommendations-and-guidelines-data-sharing - 2025-02-07

Cancer survival statistics for patients and healthcare professionals – a tutorial of real‐world data analysis

Published 30 July 2020 In this review, we explain statistical concepts targeted towards patients, clinicians and healthcare professionals that summarize cancer patient survival under the assumption that other causes of death exist. Specifically, we explain the appropriate use, interpretation and assumptions behind statistical methods for competing risks, loss in life expectancy due to cancer and c

https://www.lupop.lu.se/article/cancer-survival-statistics-patients-and-healthcare-professionals-tutorial-real-world-data-analysis - 2025-02-07

Avoiding dynastic, assortative mating, and population stratification biases in Mendelian randomization through within-family analyses

Published 31 July 2020 Estimates from Mendelian randomization studies of unrelated individuals can be biased due to uncontrolled confounding from familial effects. Here we describe methods for within-family Mendelian randomization analyses and use simulation studies to show that family-based analyses can reduce such biases. Read more here.

https://www.lupop.lu.se/article/avoiding-dynastic-assortative-mating-and-population-stratification-biases-mendelian-randomization - 2025-02-07

Development and use of health outcome descriptors: a guideline development case study

Published 1 August 2020 McMaster GRADE Centre researchers developed ‘health outcome descriptors’ for standardizing descriptions of health outcomes and overcoming these problems to support the European Commission Initiative on Breast Cancer (ECIBC) Guideline Development Group (GDG). We aimed to determine which aspects of the development, content, and use of health outcome descriptors were valuable

https://www.lupop.lu.se/article/development-and-use-health-outcome-descriptors-guideline-development-case-study - 2025-02-07

Facilitators for using data from a quality registry in local quality improvement work: a cross-sectional survey of the Danish Cardiac Rehabilitation Database

Published 2 August 2020 Objectives: To investigate use of data from a clinical quality registry for cardiac rehabilitation in Denmark, considering the extent to which data are used for local quality improvement and what facilitates the use of these data, with a particular focus on whether there are differences between frontline staff and managers. Read more here.

https://www.lupop.lu.se/article/facilitators-using-data-quality-registry-local-quality-improvement-work-cross-sectional-survey-0 - 2025-02-07

Using aggregated data from Swedish national quality registries as tools to describe health conditions of older adults with complex needs

Published 3 August 2020 Combining National Quality Registries (NQRs) with existing National Health Registries (NHRs) might make it possible to get a wider picture of older adults health situation. The aim was to examine the feasibility of aggregating data across different NQRs and existing NHRs to explore the possibility to investigate trajectories and patterns of disease and care, specifically fo

https://www.lupop.lu.se/article/using-aggregated-data-swedish-national-quality-registries-tools-describe-health-conditions-older - 2025-02-07

FORTE: Ingen utlysning av nätverksbidrag, gästforskarbidrag, tidskriftsbidrag och konferensbidrag 2020

Published 30 July 2020 Forte har påbörjat en översyn av ett antal mindre bidragsformer. Under 2020 sker därför ingen utlysning av nätverksbidrag, tidskriftsbidrag, konferensbidrag och gästforskarbidrag. Läs mer på https://forte.se/nyhet/ingen-utlysning-av-natverksbidrag-gastforskarbid….

https://www.lupop.lu.se/article/forte-ingen-utlysning-av-natverksbidrag-gastforskarbidrag-tidskriftsbidrag-och-konferensbidrag-2020 - 2025-02-07

Corona akut-utlysning 2020

Published 4 August 2020 Med anledning av coronakrisen deltar Forte i Formas akututlysning för 2020. Utlysningen ska ge möjlighet att samla in forskningsmaterial av akut karaktär för att säkerställa framtida tillgänglighet för forskning. Forskare inom Fortes områden kan ansöka om medel för datainsamling med koppling till coronapandemin. Läs mer på https://forte.se/utlysning/akututlysning-2020.

https://www.lupop.lu.se/article/corona-akut-utlysning-2020 - 2025-02-07

Estimating Risk Ratios and Risk Differences Using Regression

Published 4 August 2020 Generalized linear models (GLMs) are often used with binary outcomes to estimate odds ratios. Though not as widely appreciated, GLMs can also be used to quantify risk differences, risk ratios, and their appropriate standard errors (1). Here, we illustrate how GLMs can be used to quantify these latter effect measures, and we demonstrate how to obtain valid standard errors. R

https://www.lupop.lu.se/article/estimating-risk-ratios-and-risk-differences-using-regression - 2025-02-07

The Epidemiologic Toolbox: Identifying, Honing, and Using the Right Tools for the Job

Published 5 August 2020 There has been much debate about the relative emphasis of the field of epidemiology on causal inference. We believe this debate does short shrift to the breadth of the field. Epidemiologists answer myriad questions that are not causal and hypothesize about and investigate causal relationships without estimating causal effects. Descriptive studies face significant and often

https://www.lupop.lu.se/article/epidemiologic-toolbox-identifying-honing-and-using-right-tools-job - 2025-02-07

Helpful and challenging aspects of breastfeeding in public for women living in Australia, Ireland and Sweden: a cross-sectional study

Published 10 August 2020 Breastfeeding in public continues to be contentious with qualitative evidence confirming that women face many challenges. It is therefore important to gain understanding of not only the challenges but also what women perceive is helpful to breastfeed in public. Read more at https://doi.org/10.1186/s13006-020-00281-0.

https://www.lupop.lu.se/article/helpful-and-challenging-aspects-breastfeeding-public-women-living-australia-ireland-and-sweden-cross - 2025-02-07

Data Resource Profile: Regional healthcare information platform in Halland, Sweden

Published 10 August 2020 The main categories of data collected include: demographics, care visits, other encounters, clinical data, visit-level costs, resources and occupancy. Clinical images, patient-generated data, genetics and visits outside Halland are not included in the platform. Read more at https://doi.org/10.1093/ije/dyz262.

https://www.lupop.lu.se/article/data-resource-profile-regional-healthcare-information-platform-halland-sweden - 2025-02-07