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What makes blood stem cells transform? Regulation of RNA splicing may be an answer.

By press [at] med [dot] lu [dot] se (Faculty of Medicine) - published 24 March 2023 Cristian Bellodi and Maciej Cieśla. Photo: Helena Fritz Researchers at Lund Stem Cell Center and Lund University's Faculty of Medicine have determined a novel mechanism linking the metabolism of ribonucleic acids, RNA, to the development of leukemia in myelodysplastic syndrome patients, MDS. In a study published i

https://www.stemcellcenter.lu.se/article/what-makes-blood-stem-cells-transform-regulation-rna-splicing-may-be-answer - 2025-04-25

From vision to reality: 20 years of cutting-edge research at Lund Stem Cell Center

By alexis [dot] bento_luis [at] med [dot] lu [dot] se (Alexis Luis) - published 13 April 2023 In 2023, the Lund Stem Cell Center turns 20 years old. This will be celebrated with a conference attended by some of the world's leading stem cell researchers. Image: iStock/Maksim Tkachenko For two decades, researchers at Lund University's strategic research area, Lund Stem Cell Center, have focused on d

https://www.stemcellcenter.lu.se/article/vision-reality-20-years-cutting-edge-research-lund-stem-cell-center - 2025-04-25

Interdisciplinary Teams Unite to Develop Patient-Specific Disease Models

By alexis [dot] bento_luis [at] med [dot] lu [dot] se (Alexis Luis) - published 28 April 2023 Researchers from Lund Stem Cell Center are coming together with colleagues across Lund University to shape the future of healthcare. A new University-wide seed funding initiative seeking to support emerging research topics that benefit society will see interdisciplinary teams of neuroscience, medicine, an

https://www.stemcellcenter.lu.se/article/interdisciplinary-teams-lund-university-unite-develop-patient-tailored-disease-models - 2025-04-25

Decoding the Inner Workings of a Blood Stem Cell-Boosting Molecule

By alexis [dot] bento_luis [at] med [dot] lu [dot] se (Alexis Luis) - published 24 May 2023 A model of a proteasome, a protein complex which degrades unneeded or damaged proteins. Image from: Getty Images. A recent study conducted by researchers at Lund University's Lund Stem Cell Center, and published in the Journal of Biological Chemistry, has unraveled the intricate inner workings of UM171—a mo

https://www.stemcellcenter.lu.se/article/decoding-inner-workings-blood-stem-cell-boosting-molecule - 2025-04-25

New Study Reveals Astrocytes' Role in Frontotemporal Dementia

By alexis [dot] bento_luis [at] med [dot] lu [dot] se (Alexis Luis) - published 31 May 2023 An image of co-cultures with neuronal projections in purple and astrocytes in green. Image credit: Isaac Canals. Lund Stem Cell Center researchers have published a new study that reveals the role of astrocytes in the development of frontotemporal dementia (FTD). Their findings, now in the journal Brain Comm

https://www.stemcellcenter.lu.se/article/new-study-reveals-astrocytes-role-frontotemporal-dementia - 2025-04-25

Investigating a cell replacement therapy for Parkinson's Disease: a Ph.D. Interview with Fredrik Nilsson

By alexis [dot] bento_luis [at] med [dot] lu [dot] se (Alexis Luis) - published 8 June 2023 Fredrik Nilsson successfully defended his Ph.D. thesis on May 10, 2023. For the last four years, Fredrik has explored the use of patient-specific cells in cell replacement therapy for Parkinson's disease to identify strategies to safeguard these transplanted cells from disease-related degeneration. In this

https://www.stemcellcenter.lu.se/article/investigating-cell-replacement-therapy-parkinsons-disease-phd-interview-fredrik-nilsson - 2025-04-25

Stem Cell Science Through the Lens of Art

By alexis [dot] bento_luis [at] med [dot] lu [dot] se (Alexis Luis) - published 9 June 2023 Lund Stem Cell Center recently hosted its Image Competition for 2023, providing a glimpse into the diverse world of stem cell science through the lens of art. The competition showcased the dedication, creativity, and scientific excellence that continue to drive our pursuit of knowledge in stem cell research

https://www.stemcellcenter.lu.se/article/stem-cell-science-through-lens-art - 2025-04-25

Exploring the Role of 'Jumping Genes' in X-Linked Dystonia-Parkinsonism

By alexis [dot] bento_luis [at] med [dot] lu [dot] se (Alexis Luis) - published 19 June 2023 Postdoctoral researcher Vivien Horvath investigates X-Linked Dystonia-Parkinsonism (XDP), a rare neurodegenerative disorder. New research is underway at Lund University, led by Dr. Vivien Horvath, a postdoctoral researcher at Lund Stem Cell Center. Supported by a new grant from the Collaborative Center for

https://www.stemcellcenter.lu.se/article/exploring-role-jumping-genes-x-linked-dystonia-parkinsonism - 2025-04-25

Mechanisms of Initiation and Suppression in Pediatric Leukemia: a Ph.D. Interview with Mohamed Eldeeb

By alexis [dot] bento_luis [at] med [dot] lu [dot] se (Alexis Luis) - published 22 June 2023 Mohamed Eldeeb defended his Ph.D. thesis on June 9, 2023. With a passion for scientific discovery with clinical impact, Mohamed has dedicated the last four years to unraveling the mysteries as to why some children develop pediatric leukemia and others don’t. His research shed light on the mechanisms that p

https://www.stemcellcenter.lu.se/article/mechanisms-initiation-and-suppression-pediatric-leukemia-phd-interview-mohamed-eldeeb - 2025-04-25

Targeted Therapies in Leukemia Research Group Joins Lund Stem Cell Center

By alexis [dot] bento_luis [at] med [dot] lu [dot] se (Alexis Luis) - published 27 June 2023 Lund Stem Cell Center welcomes the Targeted Therapies in Leukemia Research Group, led by molecular biologist Marcus Järås, as its newest member. With a strong background in translational research and a focus on developing innovative therapies, the group brings extensive expertise and a unique perspective t

https://www.stemcellcenter.lu.se/article/targeted-therapies-leukemia-research-group-joins-lund-stem-cell-center - 2025-04-25

New ATMP Center at Lund University

By katrin [dot] stahl [at] med [dot] lu [dot] se (Katrin Ståhl) - published 10 July 2023 Lund University is establishing a university-wide development center for advanced therapies, LU-ATMP. It is an effort to move medical research with the potential for new groundbreaking therapies to reach patient groups where traditional medicines are not enough. "We want to contribute to the vision of Sweden b

https://www.stemcellcenter.lu.se/article/new-atmp-center-lund-university - 2025-04-25

Cracking the Code of Human Brain Evolution: Patricia Gerdes Awarded MSCA Fellowship

By alexis [dot] bento_luis [at] med [dot] lu [dot] se (Alexis Luis) - published 8 August 2023 Patricia Gerdes is developing mini-brain models called organoids using induced pluripotent stem cells from blood or skin samples from rhesus macaques, chimpanzees, and human donors. The image on the right shows an example of a rhesus macaque organoid. Patricia Gerdes, a postdoctoral researcher specializin

https://www.stemcellcenter.lu.se/article/cracking-code-human-brain-evolution-patricia-gerdes-awarded-msca-fellowship - 2025-04-25

EU funding for killer cells that fight cancer

By asa [dot] hansdotter [at] med [dot] lu [dot] se (Åsa Hansdotter) - published 24 August 2023 Researchers at Lund University, Rigshospitalet Copenhagen, Hannover Medical School and the biopharma company Amniotics will investigate how natural killer cells can be tailored for the treatment of AML, glioblastoma and pancreatic cancer. Photo: iStock. As certain tumor cells are able to conceal themselv

https://www.stemcellcenter.lu.se/article/eu-funding-killer-cells-fight-cancer - 2025-04-25

Stem cell researcher Anna Falk heads Lund University's Center for Advanced Therapies

By tove [dot] smeds [at] med [dot] lu [dot] se (Tove Smeds) - published 11 September 2023 Anna Falk. Photo: Tove Smeds. Anna Falk, professor at Lund University's Stem Cell Center, will be the director of the newly established Center for Advanced Therapies, LU-ATMP. "My vision is that we will accelerate the development of all the advanced therapies underway at Lund University. Together with the hea

https://www.stemcellcenter.lu.se/article/stem-cell-researcher-anna-falk-heads-lund-universitys-center-advanced-therapies - 2025-04-25

From enemy to friend – 33 million for reprogramming cancer cells

By asa [dot] hansdotter [at] med [dot] lu [dot] se (Åsa Hansdotter) - published 18 October 2023 Filipe Pereira (R) coordinates the research project which is allocated 33 million from the EIC. Together with Fábio Fiúza Rosa (L), he is also one of the founders of the company Asgard Therapeutics, partner in the EIC project. Photo: Asgard Therapeutics An international research project led from Lund Un

https://www.medicine.lu.se/article/enemy-friend-33-million-reprogramming-cancer-cells - 2025-04-25

Eric K. Fernström Nordic Prize 2023 awarded to cancer researcher

By tove [dot] smeds [at] med [dot] lu [dot] se (Tove Smeds) - published 19 October 2023 Cancer researcher Harald Stenmark, professor at the University of Oslo and Oslo University Hospital, is the recipient of Eric K. Fernström Nordic Prize 2023. Photo: Øystein Horgmo. Cancer researcher Harald Stenmark, professor at the University of Oslo and Oslo University Hospital, is the recipient of this year’

https://www.medicine.lu.se/article/eric-k-fernstrom-nordic-prize-2023-awarded-cancer-researcher - 2025-04-25

Research on inherited type 2 diabetes is awarded

By petra [dot] olsson [at] med [dot] lu [dot] se (Petra Olsson) - published 6 November 2023 Diabetes researcher Rashmi Prasad at Lund University has been awarded this year's Medeon Scholarship for her research on the inheritance of type 2 diabetes and why the disease is inherited from the mother to a greater extent. Photo: Petra Olsson. How do heritability and the fetal environment affect the risk

https://www.medicine.lu.se/article/research-inherited-type-2-diabetes-awarded - 2025-04-25

The cancer researcher and the intelligence expert

By asa [dot] hansdotter [at] med [dot] lu [dot] se (Åsa Hansdotter) - published 7 November 2023 Tony Ingesson and David Gisselsson Nord. Photo: Åsa Hansdotter David Gisselsson Nord and Tony Ingesson both love spy novels and have a nerdy interest in history. Their shared curiosity resulted in an interdisciplinary collaboration about how it might be possible to inspire smarter cancer treatment with

https://www.medicine.lu.se/article/cancer-researcher-and-intelligence-expert - 2025-04-25

Children with breath-holding spells undergo unnecessary diagnostic interventions

By asa [dot] hansdotter [at] med [dot] lu [dot] se (Åsa Hansdotter) - published 24 November 2023 Image: iStock/Zanuck Breath-holding spells are common in young children and are benign. Yet children often undergo unnecessary diagnostic interventions when seeking medical care. This is because there are no national or international guidelines on how to assess children in these cases. A team of resear

https://www.medicine.lu.se/article/children-breath-holding-spells-undergo-unnecessary-diagnostic-interventions - 2025-04-25

New study: Lost brain function restored after stroke

By tove [dot] smeds [at] med [dot] lu [dot] se (Tove Smeds) - published 30 November 2023 Image: iStock. Researchers have succeeded in restoring lost brain function in mouse models of stroke using small molecules that in the future could potentially be developed into a stroke therapy. “Communication between nerve cells in large parts of the brain changes after a stroke and we show that it can be pa

https://www.medicine.lu.se/article/new-study-lost-brain-function-restored-after-stroke - 2025-04-25