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Research groups in close collaboration in Malmö have shed light on the pathway whereby a common genetic risk variant leads to impaired mitochondrial function of insulin cells. The variant in question impairs the capacity to secrete insulin and increases the risk of developing diabetes. The discovery is published in the highly ranked scientific journal Cell Metabolism. It is widely established that

https://www.ludc.lu.se/article/disturbance-cellular-power-plant-increases-risk-diabetes - 2025-12-03

Researchers are now asking the question the other way around. They want to know why some diabetic patients do not develop complications. What is protecting them? The PROLONG study may provide the answer. - The majority of diabetics will over time develop severe or lethal complications, but 10-15 percent never do. They are the ones we are interested in the PROLONG study, explains Valeriya Lyssenko

https://www.ludc.lu.se/article/why-are-some-diabetics-free-complications - 2025-12-03

The professors Patrik Brundin and Leif Groop have from the European Research Council (ERC) been awarded the Advanced Grant for 2010. The Advanced Grants are awarded to support excellent and innovative research performed or led by established and wold leading research leaders.Leif Groop researches about genetic causes to Type 2 Diabetes. The project for which he receivs the award for is called "Gen

https://www.ludc.lu.se/article/two-world-leading-researchers-receivs-erc-advanced-grant - 2025-12-03

Type 2 Diabetes is the fastest growing disease in the world of today. The cause is that we are not biologically adapted to our way of living. The highest increase of diabetes occurs in countries where the living standards increases very fast. Only 20 years ago the disease was almost unknown in the developing countries. Today it is very common, only in China nearly 100 millions suffers from diabete

https://www.ludc.lu.se/article/collision-between-genes-and-life-style - 2025-12-03

DPP-4 inhibitors are a group of drugs used to treat type 1 diabetes that lower high blood usgar levels by stimulating insulin production in the body. Researchers at Lund University in Sweden have now discovered that DPP-4 inhibitors are also effective against low blood sugar levels. The study, which was carried out on mice, has been published in the journal Diabetologia. “If these inhibitors also

https://www.ludc.lu.se/article/diabetes-drug-could-protect-against-low-blood-sugar - 2025-12-03

Charlotte Ling, researcher at Lund University Diabetes Centre, receives this year´s Novo Nordisk Foundation Excellence Project grant, five millions Danish crowns allocated during five years. Her project is about exploring whether epigenetic factors are underlying the development of Type 2 Diabetes. - This means very much to me and my research group. We will be able to expand and it will speed up t

https://www.ludc.lu.se/article/large-grant-exporing-epigenetics-diabetes - 2025-12-03

No one can explain this strange phenomenon. The majority of type 2 diabetics who undergo metabolic surgery recover from diabetes only a few days after the procedure, long before any weight loss has occurred. Now researchers at Lund University Diabetes Centre plan to find out what is happening by studying both patients and pigs before and after metabolic surgery. - Since the recovery from diabetes

https://www.ludc.lu.se/article/how-can-metabolic-surgery-cure-diabetes-so-fast - 2025-12-03

Sofia Enhörning is the younger researcher in Scandinavia who wrote the best scientific article of the year within diabetes research. This means the Scandinavian Society for the Study of Diabetes (SSSD) which gives away the prize to her at the recent congress in Reykjavik.  - Really positive. And an acknowledgement that we have discovered something that others also find important, says Sofia Enhörn

https://www.ludc.lu.se/article/prize-best-scientific-article-scandinavia - 2025-12-03

Despite the disappointing results in trying to treat children suffering from type 1 diabetes with the GAD vaccine, the treatment has not been written off entirely. DIAPREV-IT, the study in which healthy high-risk children are vaccinated, is continuing as planned, and now with more money behind it. "I am still hopeful that the GAC vaccine will work", says Helena Elding Larsson. Dr Elding Larsson is

https://www.ludc.lu.se/article/still-hope-gad-diabetes-vaccine - 2025-12-03

Professor Olle Melander at Lund University Diabetes Centre and Skåne University Hospital in Malmö recieves Heart- and Lung Foundation´s large grant of 15 millions swedish crowns. By investigating the genome in tens of thousands has Olle Melander succeeded to identify markers in the blood which increase the risk of suffering from cardiovascular diseases. The next step is to investigate the markers

https://www.ludc.lu.se/article/heart-research-recieves-15-millions-swedish-crowns - 2025-12-03

The fact that diabetes rases the risk of certain types of cancer is already well known, but the reasons have been unclear. Now researchers at Lund University in Sweden have mapped a molecular link that explains the connection between the two widespread diseases. Developing type 2 diabetes is a lengthy process. An early sign that it has begun is high levels of insulin in the blood. As long as the i

https://www.ludc.lu.se/article/molecular-link-between-diabetes-and-cancer-described - 2025-12-03

Despite of more advanced methods than in the routin care it will not be determined which kind of diabetes every fifth new diabetic patient is suffering from. In the ANDIS-project (All New Diabetics In Scania) the concepts will be sorted out. ANDIS also shows that one form of diabetes, LADA, which 15 years ago not even was described is twice as common today as type 1 diabetes. - Diabetes is a more

https://www.ludc.lu.se/article/uncertain-diagnosis-every-fifth-diabetes-patient - 2025-12-03

DPCon2012 Conference Co-chairmen George Andros, MD, and David G. Armstrong, DPM, MD, PhD, are pleased to announce that the Edward James Olmos Award for Advocacy in Amputation Prevention Honoree for 2012 is Jan Apelqvist, MD, PhD. One of the world´s most distinguished experts on the diabetic foot, diabetes-related complications and wound management, a noted researcher, a skilled clinician, a profil

https://www.ludc.lu.se/article/2012-edward-james-olmos-award-advocacy-amputation-prevention - 2025-12-03

For the eight year in a row, Diabetes Research Day is arranged by the Diabetes Programme at Lund University. Apart from several scientific lectures, two awards are handed out. The award that is presented to a PhD student at Lund University Diabetes Centre (LUDC) this year goes to Cecilia Nagorny. She receives this year´s student award in competition with a lot of other PhD students at LUDC. The re

https://www.ludc.lu.se/article/awarded-mapping-hormone-darkness - 2025-12-03

International experts has on behalf of the Swedish Research Council evaluated the first five years activity of Lund University Diabetes Centre (LUDC). The half time evaluation is underlying for the continous grant for the coming five years. All together the rating is "Very well accomplished". 2006 the Research Council and the Research Council for Environment, Agricultural Sciences and Spatial Plan

https://www.ludc.lu.se/article/scientific-grade-world-class-commendation-and-resumed-confidence - 2025-12-03

The Anders Jahre Senior Medical Prize for 2012 of one million Norwegian crowns is awarded to professor Leif Groop, coordinator of Lund University Diabetes Centre. He receives the prize for his ground-breaking research on diabetes, especially for his identification of hereditary factors that predispose to this disease group. Via extensive population-based studies Professor Groop hss shown that diab

https://www.ludc.lu.se/article/2012-jahre-prize-awarded-professor-leif-groop - 2025-12-03

Using a new method, diabetes researchers at Lund University, Sweden, have been able to reveal more of the genetic complexity behind type 2 diabetes. The new research findings have been achieved as a result of access to human insulin-producing cells from deceased donors and through not only studying one gene variant, but many genes and how thay influcence the level of the gene in pancreatic islets

https://www.ludc.lu.se/article/broader-approach-provides-new-insight-diabetes-genes - 2025-12-03

Could a capsule of insulin crystals a day stop the development of type 1 diabetes? There are indications that this could be the case. In the international TrialNet study, which follows relatives of individuals with type 1 diabetes, researchers are investigating whether oral insulin could prevent or delay the disease. Something to offerType 1 diabetes is the autoimmune form of diabetes, in which th

https://www.ludc.lu.se/article/could-oral-insulin-prevent-or-delay-diabetes - 2025-12-03

When a patient is diagnosed with type 2 diabetes, the disease has usually already progressed over several years and damage to areas such as blood vessels and eyes has already taken place. To find a test that indicates who is at risk at an early stage would be valuable, as it would enable preventive treatment to be pTextut in place. Researchers at Lund University have now identified a promising can

https://www.ludc.lu.se/article/protein-reveals-diabetes-risk-many-years-advance - 2025-12-03

Researchers at Lund University, Sweden, are studying whether it is possible to prevent obesity, diabetes and cardiovascular disease by reducing levels of the hormone vasopressin in the blood. 
- If you dilute the blood by drinking water, the body releases less of the hormone vasopressin, which can potentially lead to diabetes, says Sofia Enhörning, a doctor who has recently completed her PhD at Lu

https://www.ludc.lu.se/article/could-normal-water-prevent-diabetes-obesity-and-cardiovascular-disease - 2025-12-03