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Cognitive test results are associated with mortality and rehospitalization in heart failure: Swedish prospective cohort study

Two hundred and eighty‐one patients hospitalized for HF (mean age, 74 years; 32% women) were assessed using cognitive tests: Montreal Cognitive Assessment (MoCA), A Quick Test of Cognitive speed, Trail Making Test A, and Symbol Digit Modalities Test. The mean follow‐up time censored at rehospitalization or death was 13 months (interquartile range, 14) and 28 months (interquartile range, 29), respe

https://www.lupop.lu.se/article/cognitive-test-results-are-associated-mortality-and-rehospitalization-heart-failure-swedish - 2025-12-05

Disentangling Social-Genetic From Rearing-Environment Effects for Alcohol Use Disorder Using Swedish National Data

Investigations of social-genetic effects, whereby a social partner’s genotype affects another’s outcomes, can be confounded by the influence of the social partner’s rearing environment. We used marital information on more than 300,000 couples from Swedish national data to disentangle social-genetic from rearing-environment effects for alcohol use disorder (AUD). Read more at https://journals.sagep

https://www.lupop.lu.se/article/disentangling-social-genetic-rearing-environment-effects-alcohol-use-disorder-using-swedish-national - 2025-12-05

Early versus late initiation of GH replacement in adult-onset hypopituitarism

Adult-onset growth hormone deficiency (AGHD) is usually the last deficiency to be substituted in hypopituitarism. In children with documented GH deficiency, treatment without delay is crucial for achieving optimal effects on growth and development. In adults, it is not known whether a delay in treatment initiation influences biochemical response and the favourable physiological effects resulting f

https://www.lupop.lu.se/article/early-versus-late-initiation-gh-replacement-adult-onset-hypopituitarism - 2025-12-05

Increases in the rates of primary and revision knee replacement are reducing: a 15-year registry study across 3 continents

Rates of knee replacement (KR) are increasing worldwide. Based on population and practice changes, there are forecasts of a further exponential increase in primary knee replacement through to 2030, and a corresponding increase in revision knee replacement. We used registry data to document changes in KR over the past 15 years, comparing practice changes across Sweden, Australia, and the United Sta

https://www.lupop.lu.se/article/increases-rates-primary-and-revision-knee-replacement-are-reducing-15-year-registry-study-across-3 - 2025-12-05

Formas' annual open call 2018 is now open

In the annual open call Formas welcomes applications within its three areas of responsibility - Environment, Agricultural Sciences and Spatial Planning. The purpose of the call is to enable researchers to address self-identified research needs and is divided into three sub-calls:Research and development projectsResearch and development projects for future research leadersMobility grantsThe latter

https://www.lupop.lu.se/article/formas-annual-open-call-2018-now-open - 2025-12-05

Association of acute myocardial infarction with influenza: A nationwide observational study

Influenza may precipitate cardiovascular disease, but influenza typically peaks in winter, coinciding with other triggers of myocardial infarction (MI) such as low air temperature, high wind velocity, low atmospheric pressure, and short sunshine duration. Read more at https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0236866

https://www.lupop.lu.se/article/association-acute-myocardial-infarction-influenza-nationwide-observational-study - 2025-12-05

Patterns of urinary albumin and IgM associate with markers of vascular ageing in young to middle-aged individuals in the Malmö offspring study

Increased urinary excretion of IgM and low-grade albuminuria are associated with increased risk of cardiovascular morbidity and mortality. The objective of this study was to investigate the association between urinary IgM, albuminuria, and vascular parameters reflecting arterial structure and function. Read more at https://bmccardiovascdisord.biomedcentral.com/articles/10.1186/s12872-020-01638-3

https://www.lupop.lu.se/article/patterns-urinary-albumin-and-igm-associate-markers-vascular-ageing-young-middle-aged-individuals - 2025-12-05

Mental health and academic performance: a study on selection and causation effects from childhood to early adulthood

An inverse relationship between mental health and academic achievement is a well-known phenomenon in the scientific literature. However, how and when this association develops is not fully understood and there is a lack of longitudinal, population-based studies on young children. Early intervention is important if associations are to be found already during childhood. The aim of the present study

https://www.lupop.lu.se/article/mental-health-and-academic-performance-study-selection-and-causation-effects-childhood-early - 2025-12-05

Reversal Treatment in Oral Anticoagulant-Related Intracerebral Hemorrhage—An Observational Study Based on the Swedish Stroke Register

Intracerebral hemorrhage (ICH) is the most serious adverse effect of oral anticoagulant (OAC) treatment. The effect of OAC reversal therapy on outcome is uncertain. We compared 90-day survival and functional outcome in patients with OAC-ICH who received OAC reversal therapy with those who did not. Read more at https://www.frontiersin.org/articles/10.3389/fneur.2020.00760/full

https://www.lupop.lu.se/article/reversal-treatment-oral-anticoagulant-related-intracerebral-hemorrhage-observational-study-based - 2025-12-05

The Swedish Scandinavian donations and transfusions database (SCANDAT3‐S) – 50 years of donor and recipient follow‐up

The two previous versions of the Scandinavian donations and transfusions (SCANDAT) databases, encompassing data on blood donors, blood components, transfusions, and transfused patients linked to national health registers in Sweden and Denmark up until 2012, have been used to study donor health, disease transmission, the role of donor characteristics, and more. Read more at https://onlinelibrary.wi

https://www.lupop.lu.se/article/swedish-scandinavian-donations-and-transfusions-database-scandat3-s-50-years-donor-and-recipient - 2025-12-05

The Food Addiction Denmark (FADK) Project: a combined survey and register-based study

Obesity represents a tremendous global health problem. Studies over the past decade have suggested that food addiction (FA), that is, physical cravings for certain foods – high in fat/sugar – and addiction-like overeating of these types of food, is a likely contributor to the obesity epidemic. New publication in Acta Neuropsychiatrica

https://www.lupop.lu.se/article/food-addiction-denmark-fadk-project-combined-survey-and-register-based-study - 2025-12-05

The association of single nucleotide polymorphisms (SNPs) with breast density and breast cancer survival: the Malmö Diet and Cancer Study

Genetic factors are important in determining breast density, and heritable factors account for 60% of the variation. Certain single nucleotide polymorphisms (SNPs) are associated with density and risk of breast cancer but the association with prognosis is not clear. New publication in Acta Radiologica

https://www.lupop.lu.se/article/association-single-nucleotide-polymorphisms-snps-breast-density-and-breast-cancer-survival-malmo - 2025-12-05

End-of-life care among older cancer patients with intellectual disability in comparison with the general population: a national register study.

ncreasing life expectancy for people with an intellectual disability (ID) is resulting in more persons with cancer and a greater need for end-of-life (EoL) care. There is a need for knowledge of health care utilisation over the last year of life to plan for resources that support a high quality of care for cancer patients with ID. Therefore, the aims of the study were to compare (1) health care ut

https://www.lupop.lu.se/article/end-life-care-among-older-cancer-patients-intellectual-disability-comparison-general-population - 2025-12-05

Specialist psychiatric health care utilization among older people with intellectual disability - predictors and comparisons with the general population: a national register study.

People with intellectual disability (ID) face considerable barriers to accessing psychiatric health care, thus there is a risk for health disparity. The aims of the present study were 1) to compare specialist psychiatric health care utilization among older people with ID to that with their age peers in the general population, taking into account demographic factors and co-morbidities associated wi

https://www.lupop.lu.se/article/specialist-psychiatric-health-care-utilization-among-older-people-intellectual-disability-predictors - 2025-12-05

Preterm birth and risk of sleep-disordered breathing from childhood into mid-adulthood

Preterm birth (gestational age <37 weeks) has previously been associated with cardiometabolic and neuropsychiatric disorders into adulthood, but has seldom been examined in relation to sleep disorders. We conducted the first population-based study of preterm birth in relation to sleep-disordered breathing (SDB) from childhood into mid-adulthood. New publication in International Journal of Epidemio

https://www.lupop.lu.se/article/preterm-birth-and-risk-sleep-disordered-breathing-childhood-mid-adulthood - 2025-12-05

Pain in children and adolescents with cerebral palsy – a cross-sectional register study of 3545 individuals

Pain is a common problem for individuals with cerebral palsy (CP). In Sweden, 95% of children and adolescents with CP are followed in a national follow-up programme (CPUP), which includes data on pain. The purpose of this study was to investigate the prevalence of pain based on age, sex, gross motor function and source of report (self or proxy). Pain intensity, pain site, and how much pain disturb

https://www.lupop.lu.se/article/pain-children-and-adolescents-cerebral-palsy-cross-sectional-register-study-3545-individuals - 2025-12-05

Strength in numbers? The fragility index of studies from the Scandinavian knee ligament registries

The fragility index (FI) is a metric to evaluate the robustness of statistically significant results. It describes the number of patients who would need to change from a non-event to an event to change a result from significant to non-significant. This systematic survey aimed to evaluate the feasibility of applying the FI to findings related to anterior cruciate ligament (ACL) reconstruction in th

https://www.lupop.lu.se/article/strength-numbers-fragility-index-studies-scandinavian-knee-ligament-registries - 2025-12-05

British Cardiovascular Intervention Society registry framework: a quality improvement initiative on behalf of the National Institute of Cardiovascular Outcomes Research (NICOR)

The British Cardiovascular Intervention Society (BCIS) percutaneous coronary intervention (PCI) registry is hosted by the National Institute of Cardiovascular Outcomes Research (NICOR) at Bart’s Heart Centre and collects clinical characteristics, indications, procedural details, and outcomes of all patients undergoing PCI in the UK. The data are used for audit and research to monitor and improve P

https://www.lupop.lu.se/article/british-cardiovascular-intervention-society-registry-framework-quality-improvement-initiative-behalf - 2025-12-05

Disability and Pain are the Best Predictors of Sick Leave After a Distal Radius Fracture in Men

Distal radius fracture often compromises working ability, but clinical implications are less studied in men due to its lower incidence. This study therefore describes sick leave in men with distal radius fracture, specifically exploring the impact of patient- and fracture-related factors. New publication in Journal of Occupational Rehabilitation

https://www.lupop.lu.se/article/disability-and-pain-are-best-predictors-sick-leave-after-distal-radius-fracture-men - 2025-12-05