With well over 700 000 deaths every year worldwide, kidney disease constitutes an immense health problem for patients and society. The total global number of people with kidney disease regardless of severity amounts to a staggering 600 000 000. Not surprisingly, the total health care expenditure associated with kidney disease is second to no other costs, including oncology/cancer. If acute or chro

Introduction: Routine EEG is widely used and accessible for post arrest neuroprognostication. Recent studies, using standardised EEG terminology, have proposed highly malignant EEG patterns with promising predictive ability. Objectives: To validate the performance of standardised routine EEG patterns to predict neurological outcome after cardiac arrest. Methods: In the prospective multicenter Targ

The population density concept has emerged as a proposal for the analysis of molecular dynamics results, the key characteristic of population density is the evaluation of the simultaneous occurrence of a set of relevant parameters for a system. However, despite its statistical strength, selection of the tolerance level for the comparison of different models may appear as arbitrary. This work intro

The deposition of α-synuclein fibrils is one hallmark of Parkinson's disease. Here, we investigate how ganglioside lipids, present in high amounts in neurons and exosomes, influence the aggregation kinetics of α-synuclein. Gangliosides, as well as, other anionic lipid species with small or large headgroups were found to induce conformational changes of α-synuclein monomers and catalyse their aggre

We examine how the gender of a sibling affects labor market outcomes and family formation. Identification is complicated by parental preferences: if parents prefer certain sex compositions over others, children’ s gender affects not only the outcomes of other children but also the existence of potential additional children. We employ two empirical strategies that both address this problem. First,

The objective of this study was to characterize the effects of silver nanoparticles on Pseudomonas aeruginosa. Their interactions with several conventional antibiotics and ability to induce a stress response were examined. Interactions between silver nanoparticles (AgNPs) and antibiotics against free-living cells and biofilm of P. aeruginosa were studied using the chequerboard method and time-kill

This study assesses the short and medium-term impact of extreme temperatures on population health and health-related costs in Germany. For 1999 to 2008, we link the universe of 170 million hospital admissions and all 8 million deaths with weather and pollution data at the day-county level. Extreme heat significantly and immediately increases hospitalizations and deaths. This finding holds irrespec

We explore the multiphase structure of the circumgalactic medium (CGM) probed by synthetic spectra through a cosmological zoom-in galaxy formation simulation. We employ a Bayesian method for modelling a combination of absorption lines to derive physical properties of absorbers with a formal treatment of detections, including saturated systems, and non-detections in a uniform manner. We find that i

This paper reports a numerical investigation on the effect of cavity geometry on fuel transport and mixing processes in a scramjet combustor with a single rear-wall-expansion cavity. The numerical solver and the LES methods were validated against available experimental data and the numerical results were shown in good agreement with the experiments. Effect of the cavity rear wall height on the non

Den reformation som inleddes för 500 år sedan kom att innebära betydande förändringar av gudstjänstfirandet i Sverige. I årets volym av Svenskt Gudstjänstliv utforskar vi motiven, förloppen och konsekvenserna.Gudstjänstreformernas motiv behandlas av Ragnar Holte och Thomas Girmalm. Holte tecknar den allmänna bakgrunden i en artikel om Luther och Melanchthon och deras mest kända skrifter. Thomas Gi

In various environments new agents may base their decisions on observations of actions taken by a few other agents in the past. In this paper we analyze a broad class of such social learning processes, and study under what circumstances the initial behavior of the population has a lasting effect. Our results show that this question strongly depends on the expected number of actions observed by new

Background: Late health consequences of treatment for childhood leukemia are well documented. Although individuals with Down syndrome (DS) have a substantially increased risk of leukemia, information on late effects in this group is almost nonexistent. The aim of this study was to evaluate the mortality and morbidity among 5-year leukemia survivors with DS. Procedure: We compared 5-year leukemia s

Trots allt prat om sekularisering är predikan ännu den i särklass vanligaste formen av offentligt tal i vårt land. Predikanter träder bokstavligen upp ”i tid och otid” (2 Tim. 4:2), liksom de har gjort genom hela kyrkans historia. De sex artiklarna i denna årsbok handlar om predikan både historiskt (”i tid”) och principiellt (”i otid”).Katarina Hallqvist och Erik Claeson har hämtat upp texter ur d