The implementation of biorefineries based on lignocellulosic materials as an alternative to fossil-based refineries calls for efficient methods for fractionation and recovery of the products. The focus for the biorefinery concept for utilisation of biomass has shifted, from design of more or less energy-driven biorefineries, to much more versatile facilities where chemicals and energy carriers can

There are a few studies that report cognitive impairment as a complication of treatment with beta- blockers. We aimed to evaluate the longitudinal association between use of beta-blockers, as a class, and incident risk of all-cause dementia, vascular dementia, Alzheimer's and mixed dementia in the prospective population-based Malmö Preventive Project. We included 18,063 individuals (mean age 68.2,

Augmentation of heat transfer must always be judged against an additional pressure loss. To this context, this paper explores slitted ribs on the turbulent flow and heat transfer characteristics in rectangular cooling channels with an aspect ratio of 4:1. A verified v2f turbulence model is applied in the present numerical simulations in the Reynolds number range from 20,000 to 80,000. The flow and

Classical dendritic cells (cDC) can be classified into two major subsets: Irf8-dependent cDC1 and Irf4-expressing cDC2. Although these subsets play distinct roles in intestinal immune homeostasis, their functions in T cell-driven colitis remain unknown. To assess the role of IRF4 expression in cDC2 in T cell-driven colitis, CD11c-Cre.Irf4fl/fl and Irf4fl/fl mice were backcrossed onto a Rag-1-/- ba

Background: Recent studies in arrhythmogenic right ventricular cardiomyopathy (ARVC) patients have drawn attention to atrial fibrillation (AF) as an arrhythmic manifestation of ARVC and as an indicator of atrial involvement in the disease progression. We aimed to assess the prevalence of AF in the Scandinavian cohort of ARVC patients and to evaluate its association with disease clinical manifestat

Objective: The TLR3/cGAS-STING-IFN signaling has recently been reported to be disturbed in colorectal cancer due to deregulated expression of the genes involved. Our study aimed to investigate the influence of potential regulatory variants in these genes on the risk of sporadic colorectal cancer (CRC) in a Czech cohort of 1424 CRC patients and 1114 healthy controls. Methods: The variants in the TL

AIMS/HYPOTHESIS: Substantial deposition of the extracellular matrix component hyaluronan (HA) is characteristic of insulitis in overt type 1 diabetes. We investigated whether HA accumulation is detectable in islets early in disease pathogenesis and how this affects the development of insulitis and beta cell mass.METHODS: Pancreas tissue from 15 non-diabetic organ donors who were positive for islet

Partnervåld är ett vida spritt folkhälsoproblem. Ämnets känsliga natur gör detsvårt att analysera, eftersom det är avgörande att kunna skilja en förändringi våld från en förändring i rapportering av våld. Med ett objektivt mått påvåld och oberoende variation i egenmakt skattar jag effekten av ökad kvinnligegenmakt på våld i nära relationer. Jag visar att den deskriptiva relationenmellan egenmakt o

Since the beginning of the Great Recession of 2008, we are witnessing a deepening of social and ecological crises. As a transdisciplinary research program, with a powerful critique of capitalist economy at its core, there is little surprise that we witness an ever-increasing body of literature of Marxist contributions to the fields of (among others) urban and sustainability studies following the c

Lake Tana is the largest lake in Ethiopia, and its lake outflowis the source of the BlueNile River that provides vital water resources for many livelihoods and downstream/international stakeholders. Therefore, it is essential to quantify and monitor the water balance of Lake Tana. However, Lake Tana is poorly gauged, with more than 50% of Lake Tana Basin being ungauged from in-situ measurements, m

Variation of the blood content of the pulmonary vascular bed during a heartbeat can be quantified by pulmonary blood volume variation (PBVV) using magnetic resonance imaging (MRI). The aim was to evaluate if PBVV differs in patients with heart failure compared to healthy controls and investigate the mechanisms behind the PBVV. Forty-six patients and 10 controls underwent MRI. PBVV was calculated f

Grupparbeten utmålas som pedagogiskt fördelaktiga och av Högskoleförordningen följer, att sådana är ett viktigt inslag i civilingenjörsutbildningen. Artikeln presenterar fallgropar och svårigheter som kan aktualiseras liksom ett antal faktorer som är väsentliga vid gruppsammansättning och examination för att optimera det aktiva lärande som ett grupparbete kan bidra till.