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Background: Studying tumor cell–T cell interactions in the tumor microenvironment (TME) can elucidate tumor immune escape mechanisms and help predict responses to cancer immunotherapy. Methods: We selected 14 pairs of highly tumor-reactive tumor-infiltrating lymphocytes (TILs) and autologous short-term cultured cell lines, covering four distinct tumor types, and co-cultured TILs and tumors at sub-
Objectives: The purpose of this study was to develop a procedure to investigate the occurrence, character and causes of magnetic resonance (MR) imaging incidents. Methods: A semi-structured questionnaire was developed containing details such as safety zones, examination complexity, staff MR knowledge, staff categories, and implementation of EU directive 2013/35. We focused on formally reported inc
The one-body density matrix has recently attracted considerable attention as a promising key quantity for the description of systems out of equilibrium. Its time evolution is given in terms of the two-body density matrix, and thus the central challenge is to find approximations to the latter. An extra layer of difficulty is added when dealing with strong electron correlations. In this work, we exp
This paper presents a novel framework comprising analytical, hydrological, and remote sensing techniques to separate the impacts of climate variation and regional human activities on streamflow changes in the Karkheh River basin (KRB) of western Iran. To investigate the type of streamflow changes, the recently developed DBEST algorithm was used to provide a better view of the underlying reasons. T
Galactic Archaeology is the study of the formation and evolution of the Milky Way through the properties of stars and stellar populations. The combination of stellar ages, chemical compositions, positions, and velocities can reveal the history of star formation and chemical enrichment in different regions of the Galaxy. A large number of stellar spectroscopic, photometric, and astrometric surveys
Background: Dialectical behavior therapy (DBT) is an evidence-based treatment for self-harm and emotion regulation difficulties. A modified version, DBT-Skills System (DBT-SS), has been developed in the USA for individuals with cognitive difficulties. The present study is a pilot study, testing the DBT-SS in a Swedish context.Methods: Six participants were treated with individual therapy and group
Software systems are increasingly depending on data, particularly with the rising use of machine learning, and developers are looking for new sources of data. Open Data Ecosystems (ODE) is an emerging concept for data sharing under public licenses in software ecosystems, similar to Open Source Software (OSS). It has certain similarities to Open Government Data (OGD), where public agencies share da
This article examines the continuities and discontinuities in the historical trajectory of the commercialisation of places. It outlines a performative approach to understanding how the process of turning cities into com- mercial products changes in time and space. Stockholm, the capital of Sweden, is used as an illustrative example of the spatio-temporal trajec- tory of commercialisation during th
I detta temanummer av Förvaltningsrättslig tidskrift (FT) har vi samlat bidrag utifrån temat FPL 50 år – Förvaltningsprocessen igår, idag och imorgon. Bidragen bygger på anföranden som presenterades vid en konferens med samma titel, som hölls den 3 mars 2021, med FT och Juridicum, Stockholms universitet som arrangörer.
Under coronapandemin har åtgärderna mot smittspridning ofta diskuterats utifrån den så kallade proportionalitetsprincipen. Denna juridiska princip, som kan verka okontroversiell, innebär att myndigheternas åtgärder ska vara nödvändiga och lämpliga för att nå ett visst mål och att fördelarna med åtgärderna ska uppväga nackdelarna. Att ”lagom är bäst” uppfattas ju ofta som något typiskt svenskt, och
ObjectiveTo report the outcomes of redo fenestrated and/or branched endovascular aortic repair (F/BEVAR in FEVAR) to rescue previous failed FEVAR.MethodsRetrospective review of all consecutive patients undergoing F/BEVAR in FEVAR at eight aortic centres including pre-, intra-, and post-operative data according to a pre-established protocol. Follow up consisted of at least yearly computed tomograph
This paper explores the US antitrust investigation into commitment by Ford, Honda, BMW and Volkswagen to comply with emission standards set out by the state of California from an EU perspective. It takes a look at the DOJ’s investigation and explores how such a case would be handled under the EU’s legal framework. First, it briefly provides the background of the U.S. case, including some political
