Bioreduction of carbonyl compounds to chiral alcohols by whole yeasts cells: process optimisation, strain design and non-conventional yeast screening
Chiral building blocks are needed for the production of drugs and fine chemicals, which requires the use of several synthetic routes to produce a specific enantiomer of interest. One promising approach to introduce chirality into molecules is the stereo-selective whole cell bioreduction of carbonyl compounds or ketones to the corresponding chiral alcohols. The aim of this thesis was to develop eff
