The atrioventricular (AV) node plays a crucial role during many supraventricular tachycardias (SVT). To better understand its function under these complex conditions, mathematical modelling has emerged as a valuable tool. The model presented here builds on a recently published 1D model of the human AV-node, consisting of a series of interacting nodes, each with separate dynamics in refractory time

Ambulatory ECG recordings are frequently corrupted by artifacts caused by, e.g., muscle activity or moving electrodes, which complicates the analysis of f-waves and motivates signal quality assessment to improve the reliability of f-wave analysis. Although many methods have been developed for assessing the quality of ECG signals in general, no method deals specifically with f-waves. This study pro

Rotavirus (RV) infections remain the leading cause of world-wide diarrhea-associated morbidity and mortality among children 200,000 deaths annually mostly in the low-income countries of Africa and Asia. Efficient clearance of the primary RV infection and protection from future re-infections is mediated by adaptive immune responses. The aim of the work presented in this thesis was to investigate th

The article analyses a case of prosecution for human smuggling. Three film crew members accompanied a Syrian refugee boy from Greece to Sweden, while recording the journey in a documentary that was screened on Swedish public television in 2015. Despite widespread recognition, they were prosecuted and found guilty of human smuggling by all the levels of the Swedish judiciary. Using a variety of mat

The gut microbiota has been associated with many diseases, including endometriosis. However, very few studies have been conducted on this topic in human. This study aimed to investigate the association between endometriosis and gut microbiota. Women with endometriosis (N=66) were identified at the Department of Gynaecology and each patient was matched with three controls (N=198) from the general p

A central endeavour in bioelectronics is the development of logic elements to transduce and process ionic to electronic signals. Motivated by this challenge, we report fully monolithic, nanoscale logic elements featuring n- and p-type nanowires as electronic channels that are proton-gated by electron-beam patterned Nafion. We demonstrate inverter circuits with state-of-the-art ion-to-electron tran

OBJECTIVE: To identify causal pathophysiological mechanisms for atherosclerosis and incident cardiovascular events using protein measurements. Approach and Results: Carotid artery atherosclerosis was assessed by ultrasound, and 86 cardiovascular-related proteins were measured using the Olink CVD-I panel in 7 Swedish prospective studies (11 754 individuals). The proteins were analyzed in relation t

Inverse problems are important in quantum mechanics and involve such questions as finding which potential give a certain spectrum or which arrangement of atoms give certain properties to a molecule or solid. Inverse problems are typically very hard to solve and tend to be very compute intense. We here show that neural networks can easily solve inverse problems in quantum mechanics. It is known tha

The purpose of this study is to evaluate our previously proposed model-based, non-invasive approach to assess atrioventricular (AV) node refractory periods during atrial fibrillation (AF) by comparing its estimates to the invasively assessed AV node refractory periods. Patients referred to the hospital for pulmonary vein isolation (PVI), being in AF upon arrival, are included in the study. Using o

The CKD-EPI creatinine-based estimation equation for glomerular filtration rate (GFR) cannot be used in children, overestimates GFR in young adults, and its combination with the KDIGO recommended pediatric CKiD (Schwartz bedside) equation causes implausible increases in estimated GFR when switching from pediatric to adult care. By establishing sex-specific creatinine growth curves for children and

Context. Continuous experimentation is used by many companies to improve their products with users data. In this study, the efficacy of continuous experimentation as used in two different types of business models (product-led or sales-led). Method. Two case companies with a product-led business model and three companies with sales-led business model were compared against each other. 14 interviewee

MicroLED technology is expected to be the technology of choice for next-generation displays. Its advantages in various applications are reviewed. The challenges of microLED manufacturing, including red microLED realization, adequate efficiency, mass transfer, and structure and process design from a system perspective, are discussed with a special emphasis on how nano-scale material science may ope

The problem of finding maximum (or minimum) witnesses of the Boolean product of two Boolean matrices (MW for short) has a number of important applications, in particular the all-pairs lowest common ancestor (LCA) problem in directed acyclic graphs (dags). The best known upper time-bound on the MW problem for n× n Boolean matrices of the form O(n2.575) has not been substantially improved since 2006

This article highlights the role of external audiences and their perceptions in analysing the politicization of EU development policy. We analyse how EU foreign assistance is understood in two different intermediary arenas of politicization – elites in different societal sectors and media – within Ukraine, a major recipient of EU aid. By investigating to what extent EU assistance is perceived to b