At the end of Run 3 of the Large Hadron Collider (LHC), the accelerator complex will be upgraded to the High-Luminosity LHC (HL-LHC) in order to increase the total amount of data provided to its experiments. To cope with the increased rates of data, radiation, and pileup, the ATLAS detector will undergo a substantial upgrade, including a replacement of the Inner Detector with a future Inner Tracke

The Vimmerby Moraine is the only significant ice-marginal moraine on the eastern side of southern Sweden, but no detailed studies exist on its formation during the final deglaciation of the Fennoscandian Ice Sheet. Through ground-penetrating radar surveys and detailed sediment logging, we provide evidence for an active, oscillating ice margin during the formation of the Vimmerby Moraine, suggestin

This study examined driver failure and traffic conflict using a driving simulator during lane-change scenarios on a 2+1 road, focusing on differences between day and night conditions. Data on driver failure status and driving behavior were captured through a survey. The study also evaluated driver performance and electrodermal activity. The findings revealed that nighttime lane changes had a short

Objectives. To estimate the incidence and prevalence of multiple sclerosis (MS) in Malmö municipality in southwestern Sweden. Materials and Methods. Multiple sources were used in the case identification process. Case ascertainment was assessed by medical chart review including examinations such as magnetic resonance imaging, cerebrospinal fluid analyses, and relevant laboratory tests. Cases were c

In order to move, fish must perform muscular work to overcome the inertial forces exerted on them by the water. This requires energy, and fish have evolved two major muscle types to perform the work, which generate the energy either aerobically (the “red muscle”), or anaerobically (the “white muscle”), and which are used for different types of activity. The energetic costs of these activities have

BACKGROUND: When more patients with congenital heart disease reach adult age, increased incidence of long-term complications, including ischemic stroke, are expected. The aim of this study was to analyze cumulative incidence of ischemic stroke, associated factors, and case fatality in adult congenital heart disease. METHODS AND RESULTS: The study is based on Swedish national registers on congenita

Polydiacetylene (PDA) holds promise as a versatile material for biosensing applications due to its unique optical properties and self-assembly capabilities. In this study, we developed a colorimetric detection biosensor system utilizing PDA and aptamer for the detection of microcystin-LR (MC-LR), a potent hepatotoxin found in cyanobacteria-contaminated environments. The biosensor was constructed b

Introduction: This study aimed to understand the influence of diet and nutrition items on gastrointestinal symptoms in patients with Hirschsprung Disease (HD). Method: An online questionnaire was created to obtain patient-reported outcomes using the multinational Holistic Care in Hirschsprung Disease Network. This was distributed in Dutch, English, German, Italian, Polish, and Swedish via patient

Dopaminergic neurons in the ventral tegmental area (VTA) and the substantia nigra pars compacta (SNpc) comprise around 75% of all dopaminergic neurons in the human brain. While both groups of dopaminergic neurons are in close proximity in the midbrain and partially overlap, development, function, and impairments in these two classes of neurons are highly diverse. The molecular and cellular mechani

High-latitude vegetation experience different temperatures than the ambient air temperature. While lacking a regional plant temperature product, we drove the dynamic ecosystem model, LPJ-GUESS, with widely used ERA5-land surface temperature (Tsurf, at radiative equilibrium) and air temperature to understand ecosystem process responses to these two temperatures. We show that tundra plants' growth i

Despite the rapid development of urban tourism, it was for a long time seen as a neglected field in tourism studies, which tended to focus on resorts and rural destinations. Cities were generally viewed as the generating, not receiving, parts of the tourist system. This lack of interest was matched by a similar disinterest of tourism in urban studies. One reason for this was the difficulty to defi

Med utgångspunkt i en etnografisk studie av den ideella gemenskapen Anonyma Narkomaner (NA) i Sverige och en genealogisk analys av NA:s beroendebegrepp undersöker denna studie varför personer som använder droger på sätt som anses olämpliga samtidigt betraktas som både klandervärda och oskyldiga.Studien använder begreppet den globala drogmoralen för att benämna de principer som styr när, var, hur oBased on an ethnographic study of Narcotics Anonymous (NA) in Sweden and a genealogical study of NA’s concept of addiction, this study examines why people who use drugs in ways that are considered inappropriate are simultaneously recognised as culpable and innocent.The study introduces the concept of the global drug ethic to represent the principles about when, where, how, and who ought and ought

Pediatric chronic pain is common and frequently results in reduced wellbeing and functioning. Limited knowledge among health care professionals has motivated a national care program for pediatric chronic pain to increase the standard of care for this group. Emphasizing a biopsychosocial approach, treatment should focus on self-management of pain and distress to increase resilience, functioning and

Introduction: The adverse health effects of sugar-sweetened beverage intake are well-established, but the implications of overall added sugar intake remain unclear. We investigated the associations between intake of added sugar and various sugar-sweetened foods and beverages and risk of 7 cardiovascular diseases in 69,705 participants aged 45–83 years (47.2% female) from the Swedish Mammography co

Over recent decades, management of people with hemophilia (PwH) has been greatly improved by scientific advances that have resulted in a rich and varied therapeutic landscape. Nevertheless, treatment limitations continue to drive innovation, and emerging options have the potential to realize further improvement. We advocate four general principles to optimize benefits from innovation: individualiz

Objective: The concept of proportionate and disproportionate functional mitral regurgitation suggests that transcatheter edge-to-edge mitral repair may benefit patients with a smaller left ventricle relative to a higher regurgitant burden. The clinical relevance of proportionality remains unknown in mitral operations for ischemic mitral regurgitation. We aimed to characterize the association betwe