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Background: In Alzheimer’s disease (AD), fibrillar tau initially occurs locally and progresses preferentially between closely connected regions. However, the underlying sources of regional vulnerability to tau pathology remain unclear. Previous brain-autopsy findings suggest that the myelin levels—which differ substantially between white matter tracts in the brain—are a key modulating factor of re

The market for electric bicycles has grown extremely and developed rapidly in recent years. To enter such a market with a new product, the development process has to be fast, and throughout the process, feedback from future potential customer(s) should be sought in order to achieve the best possible market acceptance. The article presents the design process of a pedelec e-bike central drive system

Objectives: Gait parameters can measure risks of falling and mortality and identify early stages of frailty. The use of walking aid changes gait parameters. The aim of this study was to describe differences in gait parameters among healthy adults when walking on different surfaces and under different conditions, with and without a rollator. Results: Ten healthy participants walked first without an

Bryophytes (mosses, liverworts, and hornworts) have interested researchers because of their high chemical diversity and their potential uses in pharmaceutical, food, and cosmetic industries. Specifically, long-chain polyunsaturated fatty acids (l-PUFA) such as arachidonic acid (AA) and eicosapentaenoic acid (EPA) are commonly found in bryophytes, but not in vascular plants. Bryophytes accumulate P

Background: The treatments for trochanteric fractures try to regain early mobility and limit morbidity and risk of reoperations. The most currently used dynamic hip screw (DHS) and the proximal femoral nail (PFN) are both with pros and cons. We aimed to assess the comparative effectiveness of these interventions for trochanteric fractures by evaluating the surgical performance and postoperative ou

Background: Patients in opioid substitution treatment (OST) have poorer health than the general population. Thus, they do not seek somatic health care to the extent that is medically motivated. Barriers hindering patients from seeking medical help through the conventional healthcare system result in a high degree of unmet healthcare needs. Barriers to, and facilitators of, OST patients’ healthcare

Objective: Characterise the spatiotemporal trabecular and cortical bone responses to complete spinal cord injury (SCI) in young rats. Methods: 8-week-old male Wistar rats received T9-transection SCI and were euthanised 2-, 6-, 10-or 16-weeks post-surgery. Outcome measures were assessed using micro-computed tomography, mechanical testing, serum markers and Fourier-transform infrared spectroscopy. R

Fasting during the month of Ramadan constitutes one of the five pillars of Islam. Islam is the second largest religion in Sweden. Fasting starts as the sun rises and the latest meal intake (Suhoor) is before the sun rises. The first meal intake (Iftar) is at the end of the fasting period, which is at sunset. Based on epidemiological data it is known that a large proportion of persons with diabetes

Femtosecond laser-induced cyano chemiluminescence uses femtosecond filaments to tag molecules in a flow field, and velocity information of the flow field can be obtained by observing the displacement of the tagged molecules within a known time. The one-dimensional (1D) emitting line contains 1D velocity field information, but only the velocity at the central point can be given because it is unable

The weak dielectric screening in 2D semiconducting transition metal dichalcogenides give rise to strongly bound quasiparticles, which provides a platform to investigate the diverse excitonic phenomena and correlated physics. However, how to effectively control these quasiparticles is still a challenge for their applications in optoelectronic and valleytronic devices. Herein, by means of fabricatin

Background: Working in close contacts with coworkers or the general public may be associated with transmission of invasive pneumococcal disease (IPD). We investigated whether crowded workplaces, sharing surfaces, and exposure to infections were factors associated with IPD. Methods: We studied 3,968 cases of IPD, and selected six controls for each case from the Swedish population registry with each

Background: Childhood cancer survivors (CCSs) have an increased risk of developing chronic health conditions. Evidence suggests that poor health behaviors further increase health risks. Healthcare professionals (HCPs) involved in survivorship care have a key role in providing health behavior support (HBS) but can feel limited in their ability to do so. This study aims to explore European HCPs perc

The most severe urban flooding in cold maritime climates is due to the co-action of long-duration rainfall, snowmelt, and soil frost. Increasing winter air temperature due to climate change is projected to change the magnitude and frequency of rain-on-snow (RoS) events and increase the number of freeze–thaw cycles and midwinter snowmelt. While daily rainfall records are readily available, less is

There has been an increase in HIV diagnoses among Chinese men who have sex with men international students (CMISs) in Australia. However, there is not a lot of understanding about the sexual health information of this cohort of transient students. There are often assumptions of low sexual health literacy and other vulnerabilities made about this cohort, but the actual cultural and systemic barrier

Many crucial activities in software development are linked to gaze and can potentially benefit from gaze-assisted developer tools. However, despite the maturity of eye trackers and the potential for such tools, we see very few studies of practitioners. Here, we present a systematic mapping study to examine recent developments in the field with a focus on the experimental setup of eye-tracking stud

Abstract in DanishLyttere kan bruge stød og ikke-stød på ordstammer til at forudsige de grammatiske endelser, som følger efter.

Spread of antibiotic resistance is a significant challenge for our modern health care system, and even more so in developing countries with higher prevalence of both infections and resistant bacteria. Faulty usage of antibiotics has been pinpointed as a driving factor in spread of resistant bacteria through selective pressure. However, horizontal gene transfer mediated through bacteriophages may a

Sense of Coherence (SOC), comprising comprehensibility, manageability and meaningful-ness, is important for the sense of living a good life with Late Effects of Polio (LEoP). However, there is a lack of knowledge about the meaning of these three components. The aim of this study was to explore in-depth the meaning of SOC among persons living with LEoP, in terms of comprehensibility, manageability