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Rearing in different photic and spectral environments changes the optomotor response to chromatic stimuli in the cichlid fish Aequidens pulcher
Developmental plasticity of spectral processing in vertebrates was investigated in fish by using an innate behavior, the optomotor response. Rearing blue acara (Aequidens pulcher; Cichlidae) under white lights of different intensities as well as deprivation of long wavelengths induced significant changes in the animals' responses to chromatic stimuli. Deprivation of short wavelengths had no effect
Nitric oxide radicals in leucocytes and vaginal washes of Trichomonas vaginalis -infected symptomatic and asymptomatic women
The clinical spectrum of Trichomonas vaginalis infection varies from asymptomatic to mild, moderate or severe vaginitis. Nitric oxide and other reactive nitrogen radicals produced by immune effector cells are important cytotoxic and cytostatic mediators against several microorganisms including parasites. In the present study, inducible nitric oxide synthase (iNOS) and reactive nitrogen intermediat
Synthesis of dipeptide units of the D D configuration in aqueous media by enzymatic catalysis
Novel molecularly imprinted polymer systems utilizing 4-vinylpyridine and 1-vinylimidazole as functional monomers have been developed for enantioselective recognition of carboxylic and N-protected amino acids. Non-covalent interactions between the functional monomers and the template molecules were the source of the subsequent recognition sites in the resultant polymers. The capacity of the polyme
Radiatively driven convection in ice-covered lakes: Observations, scaling, and a mixed layer model
Penetrative convection is discussed where the instability is driven by radiative heating of water below the temperature of maximum density. Convection of this type occurs in ice-covered freshwater lakes in late spring, when the snow cover vanishes and solar radiation is absorbed beneath the ice cover. The vertical temperature structure, bulk mixed layer scaling, and mixed layer deepening are exami
Polymorphism in the Calpain 10 gene influences glucose metabolism in human fat cells
Aims/hypothesis. A common G to A polymorphism (UCSNP-43) in the Calpain 10 gene was recently found to be associated with Type 11 (non-insulin-dependent) diabetes mellitus and variations in post-absorptive and insulin stimulated glucose metabolism in vivo. We aimed to study the influence of Calpain 10 polymorphism on insulin action in fat cells. Methods. Calpain 10 polymorphism (UCSNP-19, -43 or -6
Transcriptional dynamics of the embryonic stem cell switch
Recent ChIP experiments of human and mouse embryonic stem cells have elucidated the architecture of the transcriptional regulatory circuitry responsible for cell determination, which involves the transcription factors OCT4, SOX2, and NANOG. In addition to regulating each other through feedback loops, these genes also regulate downstream target genes involved in the maintenance and differentiation
Centrality dependence of pi(0) and eta production at large transverse momentum in root s(NN) = 200 GeV d+Au collisions
The dependence of transverse momentum spectra of neutral pions and eta mesons with p(T) < 16 GeV/c and p(T) < 12 GeV/c, respectively, on the centrality of the collision has been measured at midrapidity by the PHENIX experiment at the BNL Relativistic Heavy Ion Collider (RHIC) in d + Au collisions at root s(NN) = 200 GeV. The measured yields are compared to those in p + p collisions at the same roo
Guidelines for radioiodine therapy of differentiated thyroid cancer
Introduction The purpose of the present guidelines on the radioiodine therapy (RAIT) of differentiated thyroid cancer (DTC) formulated by the European Association of Nuclear Medicine (EANM) Therapy Committee is to provide advice to nuclear medicine clinicians and other members of the DTC-treating community on how to ablate thyroid remnant or treat inoperable advanced DTC or both employing large 13
Prediction of patient outcome with 2-deoxy-2-[18F]fluoro-D-glucose-positron emission tomography early during radiotherapy for locally advanced cervical cancer.
INTRODUCTION: It is difficult to assess the individual response of locally advanced cervical cancer to chemoradiation therapy during the course of treatment. We have investigated the predictive value of positron emission tomography (PET) with 2-deoxy-2-[18F]fluoro-D-glucose (FDG) early during treatment in relation to progression-free survival. METHODS: This prospective single-center clinical trial
Extending EDCA with Distributed Resource Reservation for QoS Guarantees
In this paper we describe how the contention-based medium access mechanism of 802.11e, EDCA, can be enhanced in order to allow stations to reserve medium access for their real-time applications with QoS requirements. We present our proposed scheme, which is called EDCA with resource reservation (EDCA/RR), and describe how it can be extended in order to be used in wireless multi-hop networks. EDCA/
The discrete nature of the growth and arrest of microstructurally short fatigue cracks modelled by dislocation technique
Growth of a microstructurally short edge crack in the neighbourhood of a grain boundary has been studied using a dislocation technique. Influence of the distance between the crack tip and a high-angle grain boundary was studied for 5000 load cycles. Growth rate was found to change stepwise during crack advance, both accelerating and decelerating, and finally retarding before crack arrest. Crack pr
Heat stress alters G-protein coupled receptor-mediated function and endothelium-dependent relaxation in rat mesenteric artery
Heat stress has been demonstrated to have strong cardiovascular effects. However, the underlying mechanism-mediated cardiovascular effects are still not fully understood. The present study was designed to examine if heat stress alters vascular G-protein coupled receptor-mediated vasomotion and endothelium function in rat mesenteric artery. Rats were divided into two groups, heat stress rats and co
Evidence of stress-induced hydrogen ordering in zirconium hydrides
The formation of hydrides in zirconium alloys significantly affects their mechanical properties and is considered to play a critical role in their failure mechanisms, yet relatively little is known about the micromechanical behavior of hydrides in the bulk. This paper presents the result of in situ uniaxial mechanical tensioning experiments on hydrided zircaloy-2 and zircaloy-4 specimens using ene
Suramin selectively inhibits carcinoma cell growth that is dependent on extracellular polyamines.
Polyamines are necessary for tumour cell growth. Inhibition of endogenous polyamine biosynthesis results in compensatory up-regulation of polyamine uptake. Here, the combined effect of suramin and the polyamine biosynthesis inhibitor alpha-difluoromethylornithine (DFMO) on human carcinoma cell proliferation was studied. Suramin selectively inhibited the growth of tumour cells made dependent on ext
The notion of "phonology' in dyslexia research: Cognitivism - and beyond
Phonology has been a central concept in the scientific study of dyslexia over the past decades. Despite its central position, however, it is a concept with no precise definition or status. The present article investigates the notion of 'phonology' in the tradition of cognitive psychology. An attempt is made to characterize the basic assumptions of the phonological approach to dyslexia and to evalu
Fecundability according to male serum inhibin B - a prospective study among first pregnancy planners
BACKGROUND: New biological markers of male fecundity are needed for use in large-scale epidemiological studies. We studied the association between male inhibin B and fecundability. METHODS: Four hundred and thirty Danish couples without previous reproductive experience were followed from termination of contraception until pregnancy or for a maximum of six menstrual cycles. At enrolment we obtained
Ultrasonic agitation in microchannels
This paper describes an acoustic method for inducing rotating vortex flows in microchannels. An ultrasonic crystal is used to create an acoustic standing wave field in the channel and thus induce a Rayleigh flow transverse to the laminar flow in the channel. Mixing in microchannels is strictly diffusion-limited because of the laminar flow, a transverse flow will greatly enhance mixing of the react
Diode laser absorption spectroscopy for studies of gas exchange in fruits
Gas exchange in fruits, in particular oxygen transport in apples, was studied non-intrusively using wavelength modulation diode laser absorption spectroscopy at about 761 run, applied to the strongly scattering intact fruit structure. The applicability of the technique was demonstrated by studies of the influence of the skin to regulate the internal oxygen balance and of cling film in modifying it
CYP gene polymorphisms and early menarche
Early age at menarche is a risk factor for breast cancer. A previous study reported a significant positive association between the CYP3A4*1B variant allele and early puberty. We investigated whether polymorphisms of the CYP3A4, CYP17, CYP1B1, and CYP1A2 genes predict the age at onset of menarche. Five hundred eighty-three nulliparous women between ages 17 and 35, of various ethnic backgrounds, com
