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Corporate Social Responsibility is used as an organizational strategy and with this power it has been established that it brings endless advantages, especially in market acceptance and growth of business image. In the country and in the department of Cochabamba, it is undergoing considerable development, growth and evolution, reaching the idea of it being used as a business strategy, to be include
The present study reports the state of the art on the application of factors about prototyping engineering approach, using case studies of machinery manufactured by research centers of the Universidad Mayor de San Simon (UMSS) in Cochabamba-Bo-livia, to determine guidelines that allow structuring broad, analytical and intuitive prototyping strategies. The research centers linked to the case studie
Mixtures between choline and geranic acid (CAGE) have previously been shown to insert into lipid bilayers. This may be useful for the transdermal delivery of larger pharmaceuticals, however, little is known about the mechanism of activity. By comparing the interactions between CAGE and lipid bilayers with those of a less-active, yet closely-related analogue, choline octanoic acid (CAOT), a chemica
Acquisition of irregular verb forms in L2 French: does the L1 of the learners explain the difference ? This study explores L1 effects on the production of subject-verb agreement in number (singular vs. plural) in L2 French. L1 influence has rarely been explored in detail in this context, especially compared to other factors such as input frequency of specific verb forms, singular vs plural entitie
Clonal hematopoiesis (CH) results from somatic genomic alterations that drive clonal expansion of blood cells. Somatic gene mutations associated with hematologic malignancies detected in hematopoietic cells of healthy individuals, referred to as CH of indeterminate potential (CHIP), have been associated with myeloid malignancies, while mosaic chromosomal alterations (mCAs) have been associated wit
To explore the internal flow distributions and heat transfer mechanism in different types of independent cooling modules for automotive, numerical, and experimental studies were conducted. According to the study, the independent cooling modules with parallel structure, on which the heat exchangers were located separately and close to the inlets, the performance improvement was significant. In addi
Cervical cancer is preventable by screening. In 1967, Sweden introduced a cervical screening program. Screening for high-risk human papillomavirus (hr-HPV), the causative factor of cervical cancer, is more sensitive than cytology and can be performed as a self-sample. Non-attendance to screening is a large risk factor for cervical cancer. Self-samples may improve screening attendance. The aims of
Background: People with inflammatory arthritis (IA) often experience low work ability, and up to 38% lose their jobs during the initial years after the diagnosis of IA. Aim: We explore the perceived challenges at work and identify the need for professional support among Danish people with IA. Materials/methods: Individual explorative interviews based on a hermeneutic approach. We used Graneheim an
Car sharing could support a transition away from private vehicle ownership and use. Attempts to understand participation in car sharing have primarily focused on minor and major disruptions which catalyse change in practices. This paper examines how processes of entering, continuing or exiting car sharing systems unfold in Norway, the Netherlands, Sweden and the UK. Car sharing is conceptualised a
Oxidative addition is the standard process for single-bond activation in transition metal catalysis and it is known to operate for many types of bonds, but challenging σ-bonds e. g. C(sp3)−F and C(sp3)−C(sp3) bonds are the exceptions in this respect. This short review aims at demonstrating how both α- and β-eliminations may be better options for activation of unstrained C−F and C−C single bonds. S
Objective: To delineate the full phenotypic spectrum of BCS1L-related disease, provide better understanding of the genotype–phenotype correlations and identify reliable prognostic disease markers. Methods: We performed a retrospective multinational cohort study of previously unpublished patients followed in 15 centres from 10 countries. Patients with confirmed biallelic pathogenic BCS1L variants w
Importance: Preterm delivery has been associated with future cardiometabolic disorders in women. However, the long-term risks of chronic hypertension associated with preterm delivery and whether such risks are attributable to familial confounding are unclear. Such knowledge is needed to improve long-term risk assessment, clinical monitoring, and cardiovascular prevention strategies in women. Objec
Using a nonlocal version of the center-manifold theorem and a normal form reduction, we prove the existence of small-amplitude generalized solitary-wave solutions and modulated solitary-wave solutions to the steady gravity-capillary Whitham equation with weak surface tension. Through the application of the center-manifold theorem, the nonlocal equation for the solitary wave profiles is reduced to
