AimsWe aimed to investigate the association between the exercise systolic blood pressure (SBP) response and future hypertension (HTN) in normotensive individuals referred for cycle ergometry, with special regard to reference exercise SBP values and exercise capacity.Methods and resultsIn this longitudinal cohort study, data from 14 428 exercise tests were cross-linked with Swedish national registr

Uncertainty quantification (UQ) tasks, such as sensitivity analysis and parameter estimation, entail a huge computational complexity when dealing with input-output maps involving the solution of nonlinear differential problems, because of the need to query expensive numerical solvers repeatedly. Projection-based reduced order models (ROMs), such as the Galerkin-reduced basis (RB) method, have been

A data-driven method combined with the formulations of boundary integral equations is developed for the frequency-domain analysis of parametrized acoustic systems, arising from the spatial discretization of the linear Helmholtz equation. The method derives surrogate models for the approximation of frequency response functions at selected field points via the construction of neural networks with ra

This work proposes a stochastic variational deep kernel learning method for the data-driven discovery of low-dimensional dynamical models from high-dimensional noisy data. The framework is composed of an encoder that compresses high-dimensional measurements into low-dimensional state variables, and a latent dynamical model for the state variables that predicts the system evolution over time. The t

We propose a non-intrusive reduced basis (RB) method for parametrized nonlinear partial differential equations (PDEs) that leverages models of different accuracy. From a collection of low-fidelity (LF) snapshots, parameter locations are extracted for the evaluations of high-fidelity (HF) snapshots to recover a reduced basis. Multi-fidelity Gaussian process regression (GPR) is employed to approxima

Previous research has indicated an association between the presence of the vitamin D receptor (VDR) in breast cancer tissue and a favorable prognosis. This study aimed to further evaluate the prognostic potential of VDR located in the nuclear membrane or nucleus (liganded). The VDR protein levels were analyzed using immunohistochemistry in tumor samples from 878 breast cancer patients from Lund, S

Structural health monitoring techniques aim at providing an automated solution to the threat of unsurveilled aging of structures that can have tremendous consequences in terms of fatalities, environmental pollution, and economic loss. To assess the state of damage of a complex structure, this paper proposes to fully characterize its behavior under multiple environmental and operational scenarios a

Background: Gaming disorder (GD) has been introduced as a new diagnosis in the International Classification of Disease 11 (ICD-11). Currently, there's limited understanding of how various video games may differentially contribute to the risk of developing GD. The main aim of this study was to examine the relationship between individuals' game genre preferences, their preferred games' monetization

A phase-field ductile fracture formulation for orthotropic paperboard materials is proposed, based on an anisotropic, multi-surface elastoplastic model describing the in-plane behavior of paperboard. A variational statement for the finite-step elastoplastic problem is extended to include the variational description of Griffith-type brittle fracture by a phase-field gradient term. The interaction b

Sveriges föreningskultur bidrar till att miljontals individer årligen får ta del av idrottens positiva effekter, såsom förhöjd fysisk och mental hälsa. Även samhället gynnas av en aktiv befolkning gällande exempelvis integration. Utan ideellt engagemang hade inte detta varit möjligt och det är därför av stor vikt att föreningsaktiva har tillgång till digitala verktyg som underlättar deras vardag oPromoting a healthy lifestyle through a user friendly website builder Sweden’s prominent sports club culture engages millions of people in an active lifestyle every year, benefitting both the individual and the society. Therefore, it is crucial to provide user friendly digital tools to help with administration of these associations. This master’s thesis has resulted in a digital tool that will h

Submarines constitute an important part of modern navies around the world. As they are systems with a high level of complexity, the production phase of a submarine is long and prone to flaws. The earlier these flaws are detected, the less of an impact they have monetarily and on the production timeline. SAAB Kockums build submarines in sections, in which platforms are mounted with equipment o

Manual co-speech gestures can facilitate language comprehension, especially in adverse listening conditions. However, we do not know whether gestures influence simultaneous interpreters’ language comprehension in adverse listening conditions, and if so, whether this influence is modulated by interpreting experience, or by active simultaneous interpreting (SI). We exposed 24 interpreters and 24 bil

I en tid av ökande social oro i periferierna av västeuropeiska ekonomier undersöker denna avhandling de levda erfarenheterna hos dem som bor i "platser som inte spelar någon roll." Genom att fokusera på de Gula Västarna i Frankrike, behandlar avhandlingen de socio-politiska missnöjena och aspirationerna hos invånarna i peri urban-områden, med syfte att förstå den komplexa strukturen av peri urbanaAmidst growing social unrest in the peripheries of Western European economies, this thesis investigates the lived experiences of those inhabiting “places that don’t matter.” Focusing on Yellow Vests activists in France, the thesis addresses the socio-political grievances and aspirations of peri-urban inhabitants, seeking to understand the complex fabric of peri-urban life and politics. This is don