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AI and Patients’ Rights : Transparency and information flows as situated principles in public health care

The development of artificial intelligence (AI) for medicine and health care is rapidly evolving. However, the automation, scale and data dependency of AI-driven decision-making and decision-support calls for a reassessment of principal ethical and legal norms of transparency, in the light of these novel methodologies. The quality of AI-driven health care, we argue, is depending on it. In this cha

Countercurrent distribution of lymphocytes from human peripheral blood in an aqueous two-phase system. : II. Separation into subsets of lymphocytes with distinctive functions

Lymphocytes from human peripheral blood were separated by Countercurrent distribution (CCD) in a charged aqueous two-phase system composed of Dextran T 500 and polyethylene glycol 6000. Maximal responses to the T-cell mitogens phytohemagglutinin and concanavalin A were detected in a part of the distribution corresponding to the area where the highest percentage of E rosetting cells were seen. Anti

Systematic analysis of mycobacterial acylation reveals first example of acylation-mediated regulation of enzyme activity of a bacterial phosphatase

Protein lysine acetylation is known to regulate multiple aspects of bacterial metabolism. However, its presence in mycobacterial signal transduction and virulence-associated proteins has not been studied. In this study, analysis of mycobacterial proteins from different cellular fractions indicated dynamic and widespread occurrence of lysine acetylation. Mycobacterium tuberculosis proteins regulati

Självskadebeteende : Upptäcka, förstå och behandla

Att möta människor som avsiktligt skadar sig själva är en utmanande situation. Hur förstår man vilken funktion det självskadande beteendet fyller för personen? Hur hanterar man sina egna tankar och känslor?I den här boken ges kunskap och praktisk vägledning för att skapa en konstruktiv och hjälpsam behandling och relation vid självdestruktiva handlingar. Författarna beskriver hur utredning och bed

Internetbehandling med KBT : En praktisk handbok

Internetbaserad KBT ger tillgång till fungerande behandling för psykisk ohälsa på patientens villkor. Metoden har utvecklats i snabb takt genom utbredda forskningsinsatser, där Sverige kan betraktas som världsledande inom området.Internetbehandling med KBT ger en grundlig genomgång av behandlingsarbetet med betoning på praktiska aspekter och tillämpningen i olika verksamheter. Särskilt fokus ligge

Refugees’ Integration in the Built Environment: The Sweden Case

The resettlement and integration of a displaced population into a new society faces a plethora of challenges. These range from lack of national legal frameworks to plan and implement planned relocation, to the absence of a long-term vision, inadequate funds, and poor institutional structures. The 3-year EU Erasmus+ funded REGARD Project (REbuildinG AfteR Displacement) set out to address some of th

Behandling av självskadande patienter i heldygnsvård: Fynd från forskningen

Rapporten du har framför dig handlar om hur vi bör utformaheldygnsvård för patienter med självskadebeteende. Även omdet har utvecklats fler och bättre behandlingsalternativ inomöppenvården behöver vi en god och välfungerande slutenvårdvid de tillfällen det är nödvändigt. För att göra det behöver vi vetavad den vården som ges idag har för effekter och undersöka vadsom skulle kunna göra den bättre.

Frictional interactions on Women, Peace and Security in Mali

More than 20 years after the adoption of UN Security Council Resolution 1325 on Women, Peace and Security, the international community is concerned with taking stock of its implementation in countries undergoing transitions from war to peace. This article contributes to a better understanding of the dynamics involved in implementing the Women, Peace and Security agenda through a focus on the frict

Alternative Turbulent Trace Gas Flux Measurement Methods

The eddy-covariance (EC) method is the most direct micrometeorological approach to measure the surface–atmosphere trace gases under turbulent conditions. The measurement of trace gas fluxes by eddy covariance requires fast-response instruments (higher than 1 Hz) to measure the turbulent fluctuations of vertical wind velocity and trace gas mixing ratio. For many trace gas species, such fast respons

Structure-function study of cathelicidin-derived bovine antimicrobial peptide BMAP-28 : design of its cell-selective analogs by amino acid substitutions in the heptad repeat sequences

Although BMAP-28 is a potent cathelicidin-derived bovine antimicrobial peptide, its cytotoxic activity against the human and other mammalian cells is of concern for converting it into a novel antimicrobial drug. We have identified a short leucine and isoleucine zipper sequences at the N- and C-terminals of BMAP-28, respectively. To understand the possible role of these structural elements in BMAP-

Moxifloxacin and ciprofloxacin induces S-phase arrest and augments apoptotic effects of cisplatin in human pancreatic cancer cells via ERK activation

BACKGROUND: Pancreatic cancer, one of the most dreadful gastrointestinal tract malignancies, with the current chemotherapeutic drugs has posed a major impediment owing to poor prognosis and chemo-resistance thereby suggesting critical need for additional drugs as therapeutics in combating the situation. Fluoroquinolones have shown promising and significant anti-tumor effects on several carcinoma c