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SPHERIOUSLY? The challenges of estimating sphere radius non-invasively in the human brain from diffusion MRI

The Soma and Neurite Density Imaging (SANDI) three-compartment model was recently proposed to disentangle cylindrical and spherical geometries, attributed to neurite and soma compartments, respectively, in brain tissue. There are some recent advances in diffusion-weighted MRI signal encoding and analysis (including the use of multiple so-called ’b-tensor’ encodings and analysing the signal in the

Parental morph combination does not influence innate immune function in nestlings of a colour-polymorphic African raptor

Conditions experienced during early life can have long-term individual consequences by influencing dispersal, survival, recruitment and productivity. Resource allocation during development can have strong carry-over effects onto these key parameters and is directly determined by the quality of parental care. In the black sparrowhawk (Accipiter melanoleucus), a colour-polymorphic raptor, parental m

Coding practice in national and regional kidney biopsy registries

Background: Kidney biopsy registries all over the world benefit research, teaching and health policy. Comparison, aggregation and exchange of data is however greatly dependent on how registration and coding of kidney biopsy diagnoses are performed. This paper gives an overview over kidney biopsy registries, explores how these registries code kidney disease and identifies needs for improvement of c

Prenatal exposures to mixtures of endocrine disrupting chemicals and children’s weight trajectory up to age 5.5 in the SELMA study

Exposure to endocrine disrupting chemicals (EDCs) may impact early growth, although information is limited on exposure to combination of multiple EDCs. We aimed to evaluate the effect of prenatal exposure to EDC mixtures on birthweight z-scores and childhood weight trajectories. Twenty-six proven and suspected EDCs, were analyzed in prenatal urine and blood samples from 1118 mothers participating

Health monitoring in birds using bio-loggers and whole blood transcriptomics

Monitoring and early detection of emerging infectious diseases in wild animals is of crucial global importance, yet reliable ways to measure immune status and responses are lacking for animals in the wild. Here we assess the usefulness of bio-loggers for detecting disease outbreaks in free-living birds and confirm detailed responses using leukocyte composition and large-scale transcriptomics. We s

The impact of cross-kingdom molecular forensics on genetic privacy

Recent advances in metagenomic technology and computational prediction may inadvertently weaken an individual’s reasonable expectation of privacy. Through cross-kingdom genetic and metagenomic forensics, we can already predict at least a dozen human phenotypes with varying degrees of accuracy. There is also growing potential to detect a “molecular echo” of an individual’s microbiome from cells dep

Optimum sizing of photovoltaic and energy storage systems for powering green base stations in cellular networks

Satisfying the mobile traffic demand in next generation cellular networks increases the cost of energy supply. Renewable energy sources are a promising solution to power base stations in a self-sufficient and cost-effective manner. This paper presents an optimal method for designing a photovoltaic (PV)-battery system to supply base stations in cellular networks. A systematic approach is proposed f

Treatment of Uncomplicated UTI in Males : a Systematic Review of the Literature

Background: Urinary tract infections (UTIs) affect around 20% of the male population in their lifetime. The incidence of UTIs in men in the community is 0.9–2.4 cases per 1000 aged <55 years and 7.7 per 1000 aged ≥85 years. Aim: To evaluate the outcomes of randomised controlled trials (RCTs) comparing the effectiveness of different antimicrobial treatments and durations for uncomplicated UTIs in a

Implementation and validation of the relativistic transient absorption theory within the dipole approximation

A relativistic transient absorption theory is derived, implemented and validated within the dipole approximation based on the time-dependent Dirac equation. In the non-relativistic limit, it is found that the absorption agrees with the well established non-relativistic theory based on the time-dependent Schrödringer equation. Time-dependent simulations have been performed using the Dirac equation

Responsibility of Action and Situated Cognition in Artefact—User Relationship

I discuss the dilution of responsibility of action and the idea of a symmetrical relationship between artefacts and humans. In doing so, I argue that meaning making is an activity unilaterally performed by agents, leading to an asymmetrical relationship between agents and artefacts. Therefore, the study of the one who is responsible for the action, the meaning-maker (with the capability to act) is

Sustainability transitions in manufacturing : the role of intellectual property

Intellectual property rights (IPR) form an important component for unlocking sustainable innovation. Research highlights both the positive role of IPR in incentivizing sustainable innovation and the negatives, such as delaying diffusion. We review the state-of-art debates on incentivizing sustainable innovations and the role of IPR for sustainable manufacturing industries, summarizing three main d

Evaluating the use of displacement ventilation for providing space heating in unoccupied periods using laboratory experiments, field tests and numerical simulations

Displacement ventilation is a proven method of providing conditioned air to enclosed spaces with the aim to deliver good air quality and thermal comfort while reducing the amount of energy required to operate the system. Until now, the practical applications of displacement ventilation have been exclusive to providing ventilation and cooling to large open spaces with high ceilings. The provision o

Eco-chemical mechanisms govern phytoplankton emissions of dimethylsulfide in global surface waters

The anti-greenhouse gas dimethylsulfide (DMS) is mainly emitted by algae and accounts for more than half of the total natural flux of gaseous sulfur to the atmosphere, strongly reducing the solar radiation and thereby the temperature on Earth. However, the relationship between phytoplankton biomass and DMS emissions is debated and inconclusive. Our study presents field observations from 100 freshw

Dispersed Variable-Retention Harvesting Mitigates N Losses on Harvested Sites in Conjunction With Changes in Soil Microbial Community Structure

As an alternative to clear-cutting, variable-retention harvesting is now standard forest management practice on the coast of British Columbia and in temperate forests globally, due to the benefits associated with maintaining mature forest species and forest structural diversity. Although there is some evidence that variable-retention harvesting, particularly single-tree (dispersed) retention will

Barriers and Facilitators for Implementation of Individualized Fire Safety (IFS) in Sweden

In 2010, the Swedish Civil Contingencies Agency (MSB) announced a “vision zero” of zero fire deaths in Sweden by 2050. Studies into fire deaths have identified that certain risk groups, including but not limited to older people, are overrepresented in fire death statistics in Sweden. The MSB has developed guidelines for how individualised fire safety (IFS) can be implemented in local communities f