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Simulations of high-dielectric Stockmayer fluids in hyperspherical geometry.

The static dielectric properties of Stockmayer fluids are investigated in the hyperspherical geometry, S(3). Different methods of obtaining the static dielectric constant ε(r) are compared. Tested methods include the evaluation of the Kirkwood factor, fluctuations of the total dipole moment, and a two-center potential correlation formula to obtain the dielectric constant through effective interact

Fördjupad analys av Skånes Flora – 1. Naturvårdsvärde och skyddsvärda arter

In this first article in a series based on various analyses of data from the survey of the vascular flora of the province of Skåne, southern-most Sweden, completed 1987–2007, the geographic distribution of total species richness (excluding taxa with only casual occurrences), red-listed species, rapidly declining species, recent immigrants and the Nature Conservation Value of species is mapped and

Extracellular Matrix and Its Receptors in Drosophila Neural Development

Extracellular matrix (ECM) and matrix receptors are intimately involved in most biological processes. The ECM plays fundamental developmental and physiological roles in health and disease, including processes underlying the development, maintenance, and regeneration of the nervous system. To understand the principles of ECM-mediated functions in the nervous system, genetic model organisms like Dro

Steady-state analysis of activated sludge processes with a settler model including sludge compression

A reduced model of a completely stirred-tank bioreactor coupled to a settling tank with recycle is analyzed in its steady states. In the reactor, the concentrations of one dominant particulate biomass and one soluble substrate component are modelled. While the biomass decay rate is assumed to be constant, growth kinetics can depend on both substrate and biomass concentrations, and optionally model

Impact of bilateral cataract surgery on vision-related activity limitations

PURPOSE: To evaluate patients' vision-related activity limitation before and after bilateral cataract surgery using the German version of the Catquest-9SF questionnaire. SETTING: Hanusch Hospital, Vienna, Austria, and Ophthalmic Clinic, Minden, Germany. DESIGN: Questionnaire development. METHODS: This prospective 2-center study included patients who were scheduled for bilateral cataract surgery an

Ferrochelatase: the convergence of the porphyrin biosynthesis and iron transport pathways

Ferrochelatase (also known as PPIX ferrochelatase; Enzyme Commission number 4.9.9.1.1) catalyzes the insertion of ferrous iron into PPIX to form heme. This reaction unites the biochemically synchronized pathways of porphyrin synthesis and iron transport in nearly all living organisms. The ferrochelatases are an evolutionarily diverse family of enzymes with no more than six active site residues kno

Healthy lifestyle index and risk of gastric adenocarcinoma in the EPIC cohort study

Several modifiable lifestyle factors, including smoking, alcohol, certain dietary factors and weight are independently associated with gastric cancer (GC); however, their combined impact on GC risk is unknown. We constructed a healthy lifestyle index to investigate the joint influence of these behaviors on GC risk within the European Prospective Investigation into Cancer and Nutrition (EPIC) cohor

Genetic parameters for rennet- and acid-induced coagulation properties in milk from Swedish Red dairy cows.

Milk coagulation is an important processing trait, being the basis for production of both cheese and fermented products. There is interest in including technological properties of these products in the breeding goal for dairy cattle. The aim of the present study was therefore to estimate genetic parameters for milk coagulation properties, including both rennet- and acid-induced coagulation, in Swe

Bovine chromosomal regions affecting rheological traits in rennet-induced skim milk gels.

Optimizing cheese yield and quality is of central importance to cheese manufacturing. The yield is associated with the time it takes before the gel has an optimal consistency for further processing, and it is well known that gel formation differs between individual milk samples. By identifying genomic regions affecting traits related to rennet-induced gelation, the aim of this study was to identif

Optimal proportional–integral–derivative set-point weighting and tuning rules for proportional set-point weights

In this study, design of low-order feedforward controllers from both reference signal and measurable disturbance for proportional–integral–derivative (PID) controllers is considered. The feedforward controllers from reference are equivalent to the use of a PID controller with set-point weighting. The design problem is formulated as a convex optimisation problem and then solved for a batch of proce

Quantitative Genetic Effects of Bottlenecks: Experimental Evidence from a Wild Plant Species, Nigella degenii.

Understanding the genetic consequences of changes in population size is fundamental in a variety of contexts, such as adaptation and conservation biology. In the study presented here, we have performed a replicated experiment with the plant Nigella degenii to explore the quantitative genetic effects of a single-founder bottleneck. In agreement with additive theory, the bottleneck reduced the mean

Impaired contractility and detrusor hypertrophy in cavin-1-deficient mice.

Caveolae are membrane invaginations present in a variety of cell types. Formation of caveolae depends on caveolins and on the more recently discovered family of proteins known as the cavins. Genetic ablation of caveolin-1 was previously shown to give rise to a number of urogenital alterations, but the effects of cavin-1 deletion on urogenital function remain unknown. Here we characterized detrusor

Perspective: Coulomb fluids-Weak coupling, strong coupling, in between and beyond

We present a personal view on the current state of statistical mechanics of Coulomb fluids with special emphasis on the interactions between macromolecular surfaces, concentrating on the weak and the strong coupling limits. Both are introduced for a (primitive) counterion-only system in the presence of macroscopic, uniformly charged boundaries, where they can be derived systematically. Later we sh

Gelatin-Hydroxyapatite Cryogels with Bone Morphogenetic Protein-2 and Transforming Growth Factor Beta-1 for Calvarial Defects

Over recent years, several tissue engineering techniques are used for bone regeneration. In this study gelatin-hydroxyapatite (Gelatin-HA) cryogel scaffolds were used with/without bone morphogenetic protein-2 (BMP-2) and transforming growth factor beta-1 (TGF-beta 1) to heal critical sized bone defects. Release of growth factors from the cryogels were performed up to 28 days in vitro. Moreover, in

Is intermittent androgen-deprivation therapy beneficial for patients with advanced prostate cancer?

Use of intermittent androgen-deprivation therapy (IADT) in patients with prostate cancer has been evaluated in several studies, in an attempt to delay the development of castration resistance and reduce side-effects associated with ADT. However it is still not clear whether survival is adversely affected in patients treated with IADT. In this review, we explore the available data in an attempt to

Laminar thermal performance of microchannel heat sinks with constructal vertical Y-shaped bifurcation plates

With increasing output power of integrated chips, the involved heat flux is accordingly increased. Traditional cooling methods failed to satisfy such a situation, and thus new cooling methods incorporating microchannel heat sinks with high capabilities of heat removal are necessary. In this paper, on the basis of a water-cooled smooth microchannel heat sink, vertical Y-shaped bifurcation plates ar

Phylogeography of the European rock rose Helianthemum nummularium (Cistaceae): incongruent patterns of differentiation in plastid DNA and morphology

Helianthemum nummularium is a morphologically variable species that has been subdivided into several subspecies based on indumentum characters. We investigated four of these subspecies for variation in plastid DNA and leaf and petal shape in Europe. Three size-variable mononucleotide repeat regions were amplified by means of species-specific primers and 18 combined haplotypes were identified. The