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Recipient and Donor Characteristics - Impact on Outcome after Heart Transplantation

Heart transplantation (HTx) is severely limited by a shortage of donors. This thesis aimed to investigate the effectof variables used to match donors to recipients in HTx.Methods: Data from the ISHLT registry was used to study: I: Identical versus compatible non-identical ABOmatchingin 3,589 AB HTx recipients. II: Outcomes of 94 ABO-incompatible transplants were compared to anABO-compatible group.

International Retailing as Embedded Business Models

As retailers internationalize they interact with diverse socio-political-economic environ- ments and the activities, processes, behaviours and outputs underpinning their business models evolve over time and space. Retailers are not passive, and through managerial agency they interpret the environment to compete and further their own commercial aims. Consequently, mutual interaction with the host e

A novel 33-Gene targeted resequencing panel provides accurate, clinical-grade diagnosis and improves patient management for rare inherited anaemias

Accurate diagnosis of rare inherited anaemias is challenging, requiring a series of complex and expensive laboratory tests. Targeted next-generation-sequencing (NGS) has been used to investigate these disorders, but the selection of genes on individual panels has been narrow and the validation strategies used have fallen short of the standards required for clinical use. Clinical-grade validation o

Soft x-ray emission studies of adsorbates

Soft x-ray emission spectroscopy is for the first time applied to surfaces and adsorbates. Surface sensitivity is achieved by employing synchrotron radiation in grazing incidence for the excitation. We present O K emission from adsorbed atomic oxygen on Ni(100) and Cu(100) and molecular CO on Ni(100). The observed spectral features correspond to the occupied 2p partial density of states of the ads

Making headway in climate policy mainstreaming and ecosystem-based adaptation : two pioneering countries, different pathways, one goal

Ecosystem-based adaptation (i.e. the use of ecosystem services to adapt to climate change) and its mainstreaming into municipal planning to foster sustainable transformation is receiving increasing interest from both academic and governmental bodies. However, little is known about the pathways for its systematic implementation, or the extent to which it is already mainstreamed in municipal plannin

Grey-Box Building Models for Model Order Reduction and Control

As automatic sensing and Information and Communication Technology (ICT) get cheaper, building monitoring data is easier to obtain. The abundance of data leads to new opportunities in the context of energy efficiency in buildings. This paper describes ongoing developments and first results of data-driven grey-box modelling for buildings. A Python toolbox is developed based on a Modelica library wit

Brown is the new white: consequences of white adipose tissue alterations in Huntington's disease

Huntington's disease (HD) is a devastating, inherited neurodegenerative disorder caused by an expanded CAG repeat in the huntingtin gene. Peripheral symptoms, such as skeletal muscle wasting, progressive weight loss, altered body composition and endocrine disturbances exist alongside neurodegeneration. Both the mutant gene and protein are expressed in cells and tissues throughout the body.Weight l

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In this essay we investigate ways to re-configure ethnographic practices and articulate them as diffractive. The essay problematizes the ways in which the phi- losophical concept of reflexivity can be understood as limiting for the inherent compositional character of ethnographic practices. These practices are by necessity carried out in proximity. That makes a reflexive point of departure problem

Struggling with New Media and Old Expertise: Reconstructing the Professional Role of Communication Consultancy

This study investigates how communication consultants struggle to reconstruct their professional role in the digital media landscape. The extant literature on professional roles in public relations has a tendency to render roles as static pregivens. Therefore, the purpose of this study is to contribute conceptually and empirically to role research by focusing on the process of “role-making” and ho