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Repeat procedures for recurrent colorectal liver metastases : Analysis of long-term liver regeneration and outcome

Background and aim: Repeat hepatectomy is increasingly performed for the management of recurrent colorectal liver metastases (CRLM). The aim of this study was to evaluate longterm functional liver volume (FLV) after a second hepatic procedure and to measure survival outcome. Methods: In this retrospective cohort study, patients treated for recurrent CRLM in the years 2005-2015 at two liver centers

The MAX IV imaging concept

The MAX IV Laboratory is currently the synchrotron X-ray source with the beam of highest brilliance. Four imaging beamlines are in construction or in the project phase. Their common characteristic will be the high acquisition rates of phase-enhanced images. This high data flow will be managed at the local computing cluster jointly with the Swedish National Computing Infrastructure. A common image

Plant survival in Iceland during periods of glaciation?

Aim: The paper addresses the classical question of possible plant survival in Iceland during the last glacial period in the light of a palaeobotanical record from northern Iceland, spanning the period 11,300-9000 BP, including the Younger Dryas stadial. We review the Late Cenozoic fossil plant record, the past debate on glacial plant refugia in Iceland, and the evidence for ice-free areas during t

Updated determination of chiral couplings and vacuum condensates from hadronic τ decay data

We analyze the lowest spectral moments of the left-right two-point correlation function, using all known short-distance constraints and the recently updated ALEPH V-A spectral function from τ decays. This information is used to determine the low-energy couplings L10 and C87 of chiral perturbation theory and the lowest-dimensional contributions to the operator product expansion of the left-right co

Mass reconstruction with a neural network

A feed-forward neural network method is developed for reconstructing the invariant mass of hadronic jets appearing in a calorimeter. The approach is illustrated in W→qq, where W-bosons are produced in pp reactions at SPS collider energies. The neural network method yields results that are superior to conventional methods. This neural network application differs from the classification ones in the

The axial anomaly and the lattice Dirac sea

In the hamiltonian formulation of fermions coupled to external gauge fields, the axial anomaly has a simple physical interpretation in terms of level shifting at the top of the Dirac sea. We apply this formalism to lattice QED in 1 + 1 and 3 + 1 dimensions, in order to study how the lattice regulation and small fermion mass affect the picture. For a simple choice of the E and B fields, it is possi

Industrial applications of ultrafiltration in the pharmaceutical biotechnology

In pharmaceutical biotechnology, ultrafiltration with diafiltration for recovery of fermentation products on an industrial scale is now the state-of-the-art technology. To optimise this process, DSS has developed two new concepts: (1) an optimised control system for constant permeate concentration even at varying feed streams and (2) continuous counter-current diafiltration to significantly reduce

Nerve-dependent and -independent tenascin expression in the developing chick limb bud

The extracellular matrix protein, tenascin, appears in a restricted pattern during organ morphogenesis. Tenascin accumulates along developing peripheral nerves as they leave the spinal cord and enter the limb mesenchyme (Wehrle and Chiquet, Development 110, 401-415, 1990). Here we found that most but not all tenascin deposited along growing nerves is of glial origin. By in situ hybridization with

Structure of the human ClC-1 chloride channel

ClC-1 protein channels facilitate rapid passage of chloride ions across cellular membranes, thereby orchestrating skeletal muscle excitability. Malfunction of ClC-1 is associated with myotonia congenita, a disease impairing muscle relaxation. Here, we present the cryo-electron microscopy (cryo-EM) structure of human ClC-1, uncovering an architecture reminiscent of that of bovine ClC-K and CLC tran

Silent Timber Build - Development of low frequency vibroacoustic prediction tools for lightweight wooden constructions

The goal of the Silent Timber Build project is to develop new prediction tools for timber structures. As a matter of fact, impact sound insulation in the low frequency range is a crucial point concerning satisfaction of lightweight wooden-based building residents. Floor systems are rather complex: multi-layered, multi-cavity, stiffened, with floor covering and ceiling (either rigidly connected, su

Industrial ultrafiltration systems for fermentation broth recovery

In the food & beverage, biotech and pharma industry the use of ultrafiltration to recover fermentation broth is the state-of-the-art. These Ultrafiltration systems consist commonly of three stages: (1) pre-concentration stage, (2) diafiltration, and (3) final concentration. The process mode can be either batch or continuous. In the batch processes for all stages of the concentration the same m

Supersonic jets of hydrogen and helium for laser wakefield acceleration

The properties of laser wakefield accelerated electrons in supersonic gas flows of hydrogen and helium are investigated. At identical backing pressure, we find that electron beams emerging from helium show large variations in their spectral and spatial distributions, whereas electron beams accelerated in hydrogen plasmas show a higher degree of reproducibility. In an experimental investigation of

Understanding the complex metallic element Mn. II. Geometric frustration in β−Mn, phase stability, and phase transitions

In the preceding paper [D. Hobbs, J. Hafner, and D. Spišák, Phys. Rev. B 68, 014407 (2003)], we have started an ab initio spin-density-functional study of the complex structural and magnetic phase behaviors of Mn by a detailed investigation of α−Mn. It was shown that the complex crystalline and noncollinear antiferromagnetic structures are the results of the conflicting tendencies to maximize simu

ICARUS -- An Extensible Graphical Search Tool for Dependency Treebanks

We present ICARUS, a versatile graphical search tool to query dependency treebanks. Search results can be inspected both quantitatively and qualitatively bymeans of frequency lists, tables, or dependency graphs. ICARUS also ships with plugins that enable it to interface with tool chains running either locally or remotely.

Novel tenascin variants with a distinctive pattern of expression in the avian embryo

Previous studies have shown that several forms of the glycoprotein tenascin are present in the embryonic extracellular matrix. These forms are the result of alternative splicing, which generates tenascin variants with different numbers of fibronectin type III repeats. We have used degenerate primers and PCR to isolate a novel tenascin exon from an avian genomic library. Genomic clones contained a