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Isomeric States Observed in Heavy Neutron-rich Nuclei Populated in the Fragmentation of a 208Pb Beam

Heavy neutron-rich nuclei were populated via the fragmentation of a E/A = 1 GeV Pb-208(82) beam. Secondary fragments were separated and identified and subsequently implanted in a passive stopper. By the detection of delayed gamma rays, isomeric decays associated with these nuclei have been identified. A total of 49 isomers were detected, with the majority of them observed for the first time. The n

Peripheral Blood Mitochondrial DNA as a Biomarker of Cerebral Mitochondrial Dysfunction following Traumatic Brain Injury in a Porcine Model.

Traumatic brain injury (TBI) has been shown to activate the peripheral innate immune system and systemic inflammatory response, possibly through the central release of damage associated molecular patterns (DAMPs). Our main purpose was to gain an initial understanding of the peripheral mitochondrial response following TBI, and how this response could be utilized to determine cerebral mitochondrial

Solar forcing of Holocene summer sea-surface temperatures in the northern North Atlantic

Mounting evidence from proxy records suggests that variations in solar activity have played a significant role in triggering past climate changes. However, the mechanisms for sun-climate links remain a topic of debate. Here we present a high-resolution summer sea-surface temperature (SST) record covering the past 9300 yr from a site located at the present-day boundary between polar and Atlantic su

Evidence For Multiple Photosystems In Jellyfish

Cnidarians are often used as model animals in studies of eye and photopigment evolution. Most cnidarians display photosensitivity at some point in their life-cycle ranging from extraocular photoreception to image formation in camera-type eyes. The available information strongly suggests that some cnidarians even possess multiple photosystems. The evidence is strongest within Cubomedusae where all

Distributed Management of CPU Resources for Time-Sensitive Applications

The number of applications sharing the same embedded device is increasing dramatically. Very efficient mechanisms (resource managers) for assigning the CPU time to all demanding applications are needed. Unfortunately, existing optimization-based resource managers consume too much resource themselves. In this paper, we address the problem of distributed convergence to fair allocation of CPU resourc

Dermatan sulfate epimerase 2 is the predominant isozyme in the formation of the chondroitin sulfate/dermatan sulfate hybrid structure in postnatal developing mouse brain

Chondroitin sulfate (CS) and dermatan sulfate (DS) are expressed in significant amounts in the brain and play important roles in the development of the central nervous system in mammals. CS and DS structures are often found in a single CS/DS hybrid chain. The L-iduronic acid (IdoA)-containing domain, which defines a DS-type domain, appears key to the biological functions of the CS/DS hybrid chain.

Ritualization - Hybridization - Fragmentation : The Mutability of Roman Vessels in Germania Magna AD 1–400

This PhD thesis deals with the transformation of imported vessels of Roman origin in Germania Magna during the Roman Iron Age, 1-400 AD. The concept of transformation in this context refers to the various ways these objects were interpreted, physically altered and consequently changed with regard to their function and meaning. Roman vessels in Germanic contexts are often regarded as evidence for R

Hur påverkas utfallet i ett förhandlingsexperiment av ett paket mjölk?

Den här artikeln redovisar resultaten från ett experiment av Holm och Runnemark 2013) som belyser hur ett paket mjölk påverkar utfallet i en förhandling genom att jämföra det med utfallet i en förhandling om en hypotetisk vara.Genom att beskriva förhandlingen som en situation där köpare och säljare ska förhandla om en faktiskt vara berör experimentet också frågan om betydelsen av abstrakta beskriv

Self-Renewing Human Bone Marrow Mesenspheres Promote Hematopoietic Stem Cell Expansion

Strategies for expanding hematopoietic stem cells (HSCs) include coculture with cells that recapitulate their natural microenvironment, such as bone marrow stromal stem/progenitor cells (BMSCs). Plastic-adherent BMSCs may be insufficient to preserve primitive HSCs. Here, we describe a method of isolating and culturing human BMSCs as nonadherent mesenchymal spheres. Human mesenspheres were derived

Bonden, bygden och bördigheten. Produktionsmönster och utvecklingsvägar under jordbruksomvandlingen i Skåne ca 1700-1870

Popular Abstract in Swedish Under 1700- och 1800-talet omvandlades det svenska jordbruket som en del av en euro¬peisk utveckling som uppvisar övergripande likheter. De genomgripande förändringarna och deras betydelse för den långsiktiga samhällsutvecklingen motiverar att man talar om en agrar revolution. Trots övergripande likheter rymde emellertid den agrara revolutionen såväl regio-nala som lokaThe great transformation of Swedish agriculture in the 18th and 19th centuries was part of a European-wide development sharing similar characteristics. While researchers agree that extensive agro-technological, social and institutional changes took place, opinions differ with regards to the causes, spread, timing and sequence of events. Through a systematic study of agricultural production, land u

Generation of induced neurons via direct conversion in vivo and in vitro

Popular Abstract in Swedish I min avhandling har jag tittat på möjligheten att göra om mänskliga hudceller direkt till dopaminerga nervceller. Dessa uppvisar flera egenskaper tillskrivna de dopaminerga nervceller vi hittar i hjärnan. Jag tittar även på möjligheten att transplantera dessa som hudceller i hjärnan på råttor och sen göra om dom till nervceller när de är på plats. Dessa celler bildar nCellular reprogramming is when one cell is changed into another. This involves structural modifications on the DNA of a cell resulting in a transcriptional change. This occurs naturally during development when early pluripotent cells gradually differentiate into more specialized cells that finally result in a complete organism. This is a finely orchestrated event that includes both extrinsic and i

Estimating the distribution of the G2 phase duration from flow cytometric histograms

A mathematical model, based on branching processes, is proposed to interpret BrdUrd DNA FCM-derived data. Our main interest is in determining the distribution of the G2 phase duration. Two different model classes involving different assumptions on the distribution of the G2 phase duration are considered. Different assumptions of the G2 phase duration result in very similar distributions of the S p

Validity of registration of ICD codes and prescriptions in a research database in Swedish primary care: a cross-sectional study in Skaraborg primary care database

Background: In recent years, several primary care databases recording information from computerized medical records have been established and used for quality assessment of medical care and research. However, to be useful for research purposes, the data generated routinely from every day practice require registration of high quality. In this study we aimed to investigate (i) the frequency and vali

Polymorphic drugs examined with neutron spectroscopy: Is making more stable forms really that simple?

Understanding polymorphism in pharmaceutical ingredients is a long-standing challenge in formulation science. A well-known example is paracetamol, C8H9NO2. The marketed stable form I crystallizes with corrugated molecular layers. In contrast, form II, which is thermodynamically favorable at high pressures, has relatively planar layers that can slip over each other without difficulty, but is metast

Decreasing incidence of peptic ulcer complications after the introduction of the proton pump inhibitors, a study of the Swedish population from 1974-2002

Background: Despite a decreasing incidence of peptic ulcer disease, most previous studies report a stabile incidence of ulcer complications. We wanted to investigate the incidence of peptic ulcer complications in Sweden before and after the introduction of the proton pump inhibitors (PPI) in 1988 and compare these data to the sales of non-steroid anti-inflammatory drugs ( NSAID) and acetylsalicyli