At the 2015 UN Climate Change Conference in Paris, nations around the world reached a landmark agreement to unify in an effort to combat climate change. The main goal of the Paris agreement is to strengthen the global response to the threat of climate change by keeping global temperature rise well below 2°C above pre-industrial levels and preferably to limit the temperature rise even further to 1.

Objective To update the epidemiology of anti-neutrophil cytoplasmic antibody-associated vasculitis (AAV) in a defined geographical area of southern Sweden.Methods The study area comprised 14 municipalities with a combined adult population (≥18 years) of 623 872 in 2019. All cases diagnosed with AAV in 1997–2019 in the study area were included in the estimate of incidence. Diagnosis of AAV was veri

Background: No reliable instruments exist to measure prognostic awareness and its psychological and behavioral impacts for patients with advanced cancer. Methods: We developed the Prognostic Awareness Impact Scale (PAIS) using a qualitative approach. During phase 1, we convened a working group with a transdisciplinary team of clinicians from oncology (n = 2), psychology (n = 2), psychiatry (n = 1)

Objective: 1-2 ‰ of newborns in Sweden are identified with a permanent, habilitation- required hearing impairment at neonatal hearing screening. Traditionally, focus is on the child when diagnosed; the parents’ needs and concerns are not always recognised. The current study aims to elucidate parents’ narratives of their experiences of the process of diagnosis and habilitation of their child with c

Palliative care supports referring colleagues in multiples ways. This support to referring colleagues is not often explored in the literature, yet the psychological concept that best describes it is the holding environment. The holding environment is the relational space palliative care offers referring clinicians for processing emotions and information. Using the case of Gloria, a patient living

A 39-year-old nulliparous woman with a previously known cervical myoma was admitted to the obstetrics department during the first trimester with complaints of severe abdominal pain, lack of bowel movements and the suspicion of a clinical bowel obstruction. Because no literature on this exact condition could be found, clinical decisions were based on reports and practice in similar situations. Ultr

BACKGROUND: Imaging ovarian cancer (OC) includes evaluating peritoneal carcinomatosis (PC) and enlarged cardio phrenic lymph nodes (CPLN) by computed tomography (CT), and thorough evaluation is tedious work. A "CT short score" with high-risk CT parameters might be a more pragmatic approach, but it is not known if such a short score associates with aggressive OC subtypes and impaired OC survival. F

Background: Bioactive adrenomedullin (bio-ADM) is a vasoactive peptide with a key role in reducing vascular hyperpermeability and improving endothelial stability during infection, but it also has vasodilatory properties. Bioactive ADM has not been studied in conjunction with acute respiratory distress syndrome (ARDS), but it has recently been shown to correlate with outcomes after severe COVID-19.

This paper investigates the use of self-funded commitment contracts to support individuals in achieving their goals of increased physical activity. We compare the effect of soft (non-incentivised) commitment contracts with hard (incentivised) contracts using a randomised experiment with 1629 members of a large gym in Stockholm, Sweden. We find a significant positive impact of being offered a hard

Molecular oxygen is essential for most living species. Consequently, hypoxic or ischemic conditions are major cellular stressors and prominent pathological features in ischemic stroke. Stroke is a global health problem and remains the second leading cause of death or disability worldwide. Current management of the disease focuses on rapid reperfusion by thrombolysis or thrombectomy but these thera

Ett alternativ för att studera immunceller i cellkulturer utan djurprodukter Cancer är ett samlingsnamn för en rad olika sjukdomar som kan uppstå var som helst i människokroppen. Tillståndet kännetecknas av att tumörer bildas i en viss kroppsdel som kan spridas till andra delar. Tumörer är komplexa strukturer som inte bara innehåller cancerceller. Cancercellerna i en tumör omringas av en så-kallaThe use of cancer cell cultures, including immune cells, is essential in cancer research for developing immunotherapies in pre-clinical investigations. However, so far, a large number of animal-derived products are utilised in cell culturing, where experimental variations and reproducibility problems have been reported. Most studies have also only investigated the differentiation of monocytes into

This article highlights how an aesthetics of religion approach generates significant new insights into well-researched textual material. It does so by looking at Chinese Buddhist biographies focusing on how the world of smell is communicated. Academically established ways of approaching biographies elucidate their historical background and analyze narrative patterns. By looking at the Biographies

Background: Early blight, caused by the necrotrophic fungal pathogen Alternaria solani, is an economically important disease affecting the tuber yield worldwide. The disease is mainly controlled by chemical plant protection agents. However, over-using these chemicals can lead to the evolution of resistant A. solani strains and is environmentally hazardous. Identifying genetic disease resistance fa