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JitterTime 1.0—Reference Manual

This technical report describes JitterTime, a Matlab toolbox for calculating the time-varying state covariance of a mixed continuous/discrete linear system driven by white noise. It also integrates a quadratic cost function for the system. The passing of time and the updating of the discrete-time systems are explicitly managed by the user in a simulation run. Since the timing is completely handled

Polyacrylamides as immobilization supports for use of hydrolytic enzymes in organic media

Polyacrylamide beads and celite were used for immobilization of bovine α-chymotrypsin and lipase B from Candida antarctica. Polyacrylamides with a high degree of cross-linking afforded high catalytic rates when used as immobilization matrices. Derivatization of the polymer with carboxyl and tertiary amino groups prior to immobilization caused no significant changes in α-chymotrypsin behavior. The

Effects of acetonitrile-water mixtures on α-chymotrypsin catalyzed dipeptide synthesis

α-Chymotrpysin (EC 3.4 21.1) was immobilized by deposition on celite and subsequent cross-linking with glutaraldehyde. The effects of different mixtures of aqueous buffer and acetonitrile on the immobilized preparation were evaluated using a dipeptide synthesis as model reaction. The initial reaction rate at 6-95% of water increased with increasing water content. The maximum yield of peptide had t

loga, a nonlinear scale of time (e104), for tpt and tbn

#104_loga, a nonlinear scale of time, for tpt, tbn. “loga, a nonlinear scale of time” refers to the illusion of nonlinear time perception. This idea suggests that our estimation of time intervals whether on a small (milliseconds) or large (decades) scale should be logarithmic, giving us a subjective experience very different from clock or calendar. Of course, our perception of time is influenced b

A review and evaluation of circular business model innovation tools

The circular economy has been heralded as a potential driver for sustainable development by business, academia, and policymakers. In a future circular economy, new business models are needed that slow, close and narrow resource loops to address key resource and climate challenges. After a phase of excitement and inspiration, an operationalization phase needs to start to ensure the best possible im

Increased medical attention needed for frail elderly initially admitted to the emergency department for lack of community support

The demographic changes in society with growing numbers of elderly subjects will inevitably increase admission rates to acute emergency departments (AMU). Early discharge might augment emergency readmissions due to a relapse in medical conditions. Our aim was to study precipitating factors in frail elderly patients who got the diagnosis 'lack of community support' after initial medical examination

Frequent disc photography and computerized perimetry in eyes with optic disc haemorrhage. A pilot study

Two patients (one with glaucoma with field loss, one with ocular hypertension) with previously known optic disc haemorrhage were followed with frequent disc photography, computerized perimetry and tonometry for a period of one year. Nine haemorrhages were seen in three of the four eyes studied. Three bleedings showed sudden enlargements, interpreted as re-bleedings, during the absorption phase. Ha

Computerized perimetry in glaucoma management

The present article discusses the role of computerized perimetry in the management of patients with suspect and manifest glaucoma. The value of visual field examination is compared to that of inspection and photography of the optic disc and to some extent to retinal nerve fibre layer photography. Computerized perimetry is related to standard manual visual field examination. Guidelines are offered

Changes in differential threshold in patients with glaucoma during prolonged perimetry

Patients with chronic open-angle glaucoma and others suspected of having glaucoma were subjected to continuous contrast threshold measurement by automatic and manual perimetric techniques. The results show that an increase of contrast threshold over time is a frequent finding in glaucoma patients and that this increment can be large, especially at points close to existing field defects. it is repr

The spectrum of diseases causing fever of unknown origin in Turkey : a multicenter study

OBJECTIVE: The purpose of this trial was to determine the spectrum of diseases with fever of unknown origin (FUO) in Turkey.METHODS: A prospective multicenter study of 154 patients with FUO in twelve Turkish tertiary-care hospitals was conducted.RESULTS: The mean age of the patients was 42+/-17 years (range 17-75). Fifty-three (34.4%) had infectious diseases (ID), 47 (30.5%) had non-infectious inf

Acute respiratory distress syndrome due to Cryptococcus albidus pneumonia : case report and review of the literature

Although cryptococcal infections due to Cryptococcus neoformans are frequently reported in the immunosuppressed patients, infections related to other Cryptococcus spp. are rarely reported. We are reporting a case of pulmonary infection and ARDS due to C. albidus in a patient receiving immunosuppressive therapy because of Still's disease. The diagnosis was made by tissue biopsy and culture. The pat

Tumor genome wide DNA alterations assessed by array CGH in patients with poor and excellent survival following operation for colorectal cancer

Genome wide DNA alterations were evaluated by array CGH in addition to RNA expression profiling in colorectal cancer from patients with excellent and poor survival following primary operations. DNA was used for CGH in BAC and cDNA arrays. Global RNA expression was determined by 44K arrays. DNA and RNA from tumor and normal colon were used from cancer patients grouped according to death, survival o

Analysis of the apparent nuclear modification in peripheral Pb–Pb collisions at 5.02 TeV

Charged-particle spectra at midrapidity are measured in Pb–Pb collisions at the centre-of-mass energy per nucleon–nucleon pair s NN =5.02 TeV and presented in centrality classes ranging from most central (0–5%) to most peripheral (95–100%) collisions. Possible medium effects are quantified using the nuclear modification factor (R AA ) by comparing the measured spectra with those from proton–proton