Search results

Filter

Filetype

Your search for "*" yielded 533384 hits

ESO Guideline on covert cerebral small vessel disease

‘Covert’ cerebral small vessel disease (ccSVD) is common on neuroimaging in persons without overt neurological manifestations, and increases the risk of future stroke, cognitive impairment, dependency, and death. These European Stroke Organisation (ESO) guidelines provide evidence-based recommendations to assist with clinical decisions about management of ccSVD, specifically white matter hyperinte

Probing dark matter with disappearing tracks at the LHC

Models where dark matter is a part of an electroweak multiplet feature charged particles with macroscopic lifetimes due to the charged-neutral mass split of the order of pion mass. At the Large Hadron Collider, the ATLAS and CMS experiments will identify these charged particles as disappearing tracks, since they decay into a massive invisible dark matter candidate and a very soft charged Standard-

Development of an experimental ex vivo wound model to evaluate antimicrobial efficacy of topical formulations

Wound infections are considered a major cause for wound-associated morbidity. There is a high demand for alternative, robust, and affordable methods that can provide relatable and repro-ducible results when testing topical treatments, both in research and in the pharmaceutical industry. Here we present an ex vivo wound infection model using porcine skin and a burn wounding method, allowing for the

Adolescents’ experiences of facilitators for and barriers to maintaining exercise 12 months after a group-based intervention for depression

Exercise can improve health among adolescents with depression. Understanding facilitators for and barriers to maintaining exercise among adolescents with depression may increase adherence to exercise and consequently improve health. The aim was to explore adolescents’ experiences of facilitators for and barriers to maintaining exercise after a group-based exercise intervention for depression. Inte

Acute manic state with psychotic features in a teenager with autoimmune encephalitis

INTRODUCTION: Autoimmune disorders have become increasingly acknowledged as having a more causative role in encephalitis than previously assumed. Anti-N-methyl-D-aspartate receptor encephalitis seems to be the most prevalent disorder. Symptoms of the neuropsychiatric phase in children and adolescents include abnormal behavior, seizures, and neurologic symptoms. We present a report on a teenage gir

No title

Anmeldelse af: Ditte Darko. Kort og godt om Seksuel chikane & #Metoo. Dansk Psykologisk Forlag, 2021.

Active bacterial modification of the host environment through RNA polymerase II inhibition

Unlike pathogens, which attack the host, commensal bacteria create a state of friendly coexistence. Here, we identified a mechanism of bacterial adaptation to the host niche, where they reside. Asymptomatic carrier strains were shown to inhibit RNA polymerase II (Pol II) in host cells by targeting Ser2 phosphorylation, a step required for productive mRNA elongation. Assisted by a rare, spontaneous

The need for boundary spanners in an offshore insourcing strategy

This paper presents research on the need for boundary spanners in organizations that has an offshore insourcing strategy for the IT-function. The research question addressed was: How does an offshore insourcing strategy influence the need for having boundary spanners? Empirical data was collected using a case study in three phases, including semi-structured and structured interview in a multinatio

Genomic and transcriptomic characterization of desmoplastic small round cell tumors

Desmoplastic small round cell tumor (DSRCT) is a highly aggressive soft tissue tumor primarily affecting children and young adults. Most cases display a pathognomonic EWSR1-WT1 gene fusion, presumably constituting the primary driver event. Little is, however, known about secondary genetic changes that may affect tumor progression. We here studied 25 samples from 19 DSRCT patients using single nucl

Cyclohexyl-α maltoside as a highly efficient tool for membrane protein studies

Membrane proteins (MPs) constitute a large fraction of the proteome, but exhibit physicochemical characteristics that impose challenges for successful sample production crucial for subsequent biophysical studies. In particular, MPs have to be extracted from the membranes in a stable form. Reconstitution into detergent micelles represents the most common procedure in recovering MPs for subsequent a

Special issue on spoken language in time and across time : Introduction

The idea of this special issue on Spoken language in time and across time emerged at an international symposium on this topic that we organised at Lund University on 20 September 2019. The purpose of the symposium was to celebrate important past and present achievements of spoken language research as well as past and present corpora available for such research. Some speakers reported on academic a

Diet plays a central role in parental self-treatment of children with Hirschsprung’s disease : a qualitative study

AimHirschsprung's disease is a congenital disorder requiring surgery. Most children operated on for Hirschsprung's disease experience postoperative bowel dysmotility. Although various food is known to influence bowel motility, evidence of diet's role and dietary guidelines in treatment of bowel dysfunction in Hirschsprung's disease is lacking. The aim was to explore parental experiences of dietary

CFD modeling of pyrolysis oil combustion using finite rate chemistry

This paper reports the first Computational Fluid Dynamics (CFD) model developed for biomass pyrolysis oil spray combustion using Finite-Rate Chemistry (FRC) approach. To make the CFD calculations feasible, a reduced mechanism for modeling the combustion of biomass Fast Pyrolysis Oil (FPO) based on the POLIMI 1412 mechanism and a model for eugenol oxidation was developed. The reduced mechanism cons

Abnormal glucose tolerance and lung function in children with cystic fibrosis. Comparing oral glucose tolerance test and continuous glucose monitoring

BACKGROUND: Cystic fibrosis (CF) related diabetes (CFRD) is a common complication of CF. CFRD is associated with declining lung function even before its onset. Regular screening for CFRD using oral glucose tolerance test (OGTT) is recommended. Additionally, continuous glucose monitoring (CGM) has surfaced as a possible surveillance method, but evidence for its use and concordance with OGTT has not