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Cholestatic liver damage is mediated by lymphocyte function antigen-1-dependent recruitment of leukocytes.

BACKGROUND: The role of specific adhesion molecules in cholestasis-induced leukocyte recruitment in the liver is not known. Therefore, the aim of our experimental study was to evaluate the role of lymphocyte function antigen-1 (LFA-1) in cholestatic liver injury. METHODS: C57BL/6 mice underwent bile duct ligation for 12 hours. Mice were pretreated with an anti-LFA-1 antibody or control antibody. S

Chemical sensing with laser spectroscopy

Laser spectroscopic techniques constitute powerful tools for chemical sensing. Atoms and molecules can be identified and quantified by their specific spectral signatures and the strength of the signals. A wide variety of methods for establishing spectroscopic contact with the species exist: absorption, emission, fluorescence, Raman scattering, acousto-optic, and opto-galvanic phenomena can be empl

Elicitation and management of user requirements in market-driven software development

Market-driven software development companies experience challenges in requirements management that many traditional requirements engineering methods and techniques do not acknowledge. Large markets, limited contact with end users, and strong competition forces the market-driven software development company to constantly invent new, selling requirements, frequently release new versions with an acco

Distance bounds for an ensemble of LDPC convolutional codes

An ensemble of (J, K) -regular low-density parity-check (LDPC) convolutional codes is introduced and existence-type lower bounds on the minimum distance dL, of code segments of finite length L and on the free distance dfree are derived. For sufficiently large constraint lengths v, the distances are shown to grow linearly with v and the ratio dL/v approaches the ratio dfee/v for large L. Moreover,

Fantomaten: The PHANToM för handikappade barn

The PHANToM är en uppfinning från MIT, Massachussets Institute of Technology, som möjliggör kommunikation mellan en människa och en dator med hjälp av känsel. The PHANToM är utvecklad som ett allmänt känselgränssnitt. På CERTEC har vi sett möjligheten att

Conceptual Design of a Hydraulic Valve Train System

Variable valve train systems have been brought into focus during recent years as a means to decrease fuel consumption in tomorrow’s combustion engines. In this paper an integrated approach, called simulation driven experiments, is utilised in order to aid the development of such highly dynamic systems. Through the use of systematic design methodology, a number of feasible concepts are developed. C

Estimation of line properties in the copper access network

The copper access-network operators face the challenge of developing and maintaining cost-effective digital subscriber line (DSL) services that are competitive to other broadband access technologies. The way forward is dictated by the demand of ever increasing data rates on the twisted-pair copper lines. This forces a deployment of the DSL transceivers in cabinets closer to the customers with a jo

Hepatocyte growth factor in cerebrospinal fluid differentiates community-acquired or nosocomial septic meningitis from other causes of pleocytosis.

Due to anatomical restrictions, the inflammatory response to intracerebral bacterial infections exposes swollen brain tissues to pressure and ischemia, resulting in life-threatening damage. Rapid diagnosis and immediate empirical antibiotic therapy is highly important. However, diagnosing meningitis in patients after neurosurgery is complicated, due to brain tissue damage and changes in cerebrospi

Early intervention in management of very preterm growth-restricted fetuses : 2-year outcome of infants delivered on fetal indication before 30 gestational weeks

OBJECTIVES: To describe the outcome of growth-restricted fetuses with absent or reversed end-diastolic flow (ARED) in the umbilical artery delivered on fetal indication before 30 gestational weeks.METHODS: Between 1998 and 2004, 42 fetuses with intrauterine growth restriction (IUGR) and ARED in the umbilical artery were delivered liveborn by Cesarean section on fetal indication before 30 gestation

Biological effects of a disposable, canisterless negative pressure wound therapy system.

Objective: Recent developments of negative pressure wound therapy (NPWT) systems have focused on making pumps smaller, lighter, and more portable. The recently introduced PICO system manages wound fluid through a highly breathable film within the dressing, thereby negating the need for a canister, which allows greater mobility and patient concordance. The aim of this study is to compare the biolog

On some Nonlinear Aspects of Wave Motion

In the first part of this thesis we consider the governing equations for capillary water waves given by the Euler equations with a free surface under the influence of surface tension over a flat bottom. We look for two-dimensional steady periodic waves. The problem is first transformed to a nonlinear elliptic equation in a rectangle. Using bifurcation and degree theory we then prove the existence

von Langenbeck procedures at 14 months or Wardill at 18 months for primary repair of cleft palate in adult Swedish patients with bilateral complete cleft lip and palate: A study of facial growth.

We compared facial growth in patients with bilateral complete cleft lip and palate (BCLP) in whom the palate had been repaired by the von Langenbeck procedure at the age of 14 months (L-14), or by the Wardill procedure at 18 months (W-18). A total of 151 unaffected subjects were used as a reference group. Thirty-six adult patients, 26 in the L-14 group, and 10 in the W-18 group, were investigated