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Observation of a Centrality-Dependent Dijet Asymmetry in Lead-Lead Collisions at root s(NN)=2.76 TeV with the ATLAS Detector at the LHC

By using the ATLAS detector, observations have been made of a centrality-dependent dijet asymmetry in the collisions of lead ions at the Large Hadron Collider. In a sample of lead-lead events with a per-nucleon center of mass energy of 2.76 TeV, selected with a minimum bias trigger, jets are reconstructed in fine-grained, longitudinally segmented electromagnetic and hadronic calorimeters. The tran

Molecular Rift: Virtual Reality for Drug Designers

Recent advances in interaction design have created new ways to use computers. One example is the ability to create enhanced 3D environments that simulate physical presence in the real world a virtual reality. This is relevant to drug discovery since molecular models are frequently used to obtain deeper understandings of, say, ligand protein complexes. We have developed a tool (Molecular Rift), whi

Regional differences in birth size: a comparison between the Helsinki Birth Cohort Study and contemporaneous births on the Åland Islands.

The Åland Islands were recently ranked as Finland's healthiest region with lower prevalence of several non-communicable diseases compared with the national mean. We have compared birth characteristics of 1697 individuals born on the Åland Islands between 1937 and 1944 with contemporaneous data from the Helsinki Birth Cohort Study (HBCS; n=11,808). This is a first step towards a potential future an

Parental Education and Offspring Outcomes: Evidence from the Swedish Compulsory School Reform

We use the Swedish compulsory school reform to estimate the causal effect of parental education on sons’ outcomes. To this end, we use data from the Swedish military enlistment register on the entire population of males and consider outcomes such as cognitive skills, non-cognitive skills, and various dimensions of health at the age of 18. We find positive effects of maternal education on sons' ski

Discovery-based Protein Expression Profiling Identifies Distinct Subgroups and Pathways in Leiomyosarcomas.

Soft tissue sarcomas (STS) are malignant tumors of mesenchymal origin. A substantial portion of these tumors exhibits complex karyotypes and lack characterized chromosomal aberrations. Owing to such properties, both histopathological and molecular classification of these tumors has been a significant challenge. This study examines the protein expression of a large number of human softtissue sarcom

The analgesic effect of oxygen during percutaneous coronary intervention (the OXYPAIN Trial).

Abstract Introduction: Oxygen is considered to have analgesic effects, but the evidence is weak. Oxygen may be harmful to the ischemic myocardium. The aim was to investigate the analgesic effect of oxygen during percutaneous coronary intervention (PCI) and to evaluate cardiac injury. Material and methods: The OXYPAIN was a phase II randomized trial with a double blind design. 305 patients were ran

Preparation of hydrophilic poly(3-hydroxybutyrate) macroporous scaffolds through enzyme-mediated modifications

Scaffolds made from poly(3-hydroxybutyrate) were prepared by thermally induced phase separation from solutions in dioxane at temperatures above (23 degrees C) or below the freezing point of the solvent. At 23 degrees C, gelation occured with nano-fibrous network formation. The scaffolds prepared at -12 degrees C and -25 degrees C exhibited a highly porous morphology, with pores in the range of 3-2

Status of the ESS Cryogenic System

The European Spallation Source (ESS) is a neutron science facility funded by a collaboration of 17 European countries currently under design and construction in Lund, Sweden. The centerpiece of ESS is a 2.5 GeV proton linac utilizing superconducting RF cavities operating at 2 K. In addition to cooling the SRF cavities, cryogenics is also used at ESS in the liquid hydrogen moderators surrounding th

Simulations of high-dielectric Stockmayer fluids in hyperspherical geometry.

The static dielectric properties of Stockmayer fluids are investigated in the hyperspherical geometry, S(3). Different methods of obtaining the static dielectric constant ε(r) are compared. Tested methods include the evaluation of the Kirkwood factor, fluctuations of the total dipole moment, and a two-center potential correlation formula to obtain the dielectric constant through effective interact

Fördjupad analys av Skånes Flora – 1. Naturvårdsvärde och skyddsvärda arter

In this first article in a series based on various analyses of data from the survey of the vascular flora of the province of Skåne, southern-most Sweden, completed 1987–2007, the geographic distribution of total species richness (excluding taxa with only casual occurrences), red-listed species, rapidly declining species, recent immigrants and the Nature Conservation Value of species is mapped and

Extracellular Matrix and Its Receptors in Drosophila Neural Development

Extracellular matrix (ECM) and matrix receptors are intimately involved in most biological processes. The ECM plays fundamental developmental and physiological roles in health and disease, including processes underlying the development, maintenance, and regeneration of the nervous system. To understand the principles of ECM-mediated functions in the nervous system, genetic model organisms like Dro

Steady-state analysis of activated sludge processes with a settler model including sludge compression

A reduced model of a completely stirred-tank bioreactor coupled to a settling tank with recycle is analyzed in its steady states. In the reactor, the concentrations of one dominant particulate biomass and one soluble substrate component are modelled. While the biomass decay rate is assumed to be constant, growth kinetics can depend on both substrate and biomass concentrations, and optionally model

Impact of bilateral cataract surgery on vision-related activity limitations

PURPOSE: To evaluate patients' vision-related activity limitation before and after bilateral cataract surgery using the German version of the Catquest-9SF questionnaire. SETTING: Hanusch Hospital, Vienna, Austria, and Ophthalmic Clinic, Minden, Germany. DESIGN: Questionnaire development. METHODS: This prospective 2-center study included patients who were scheduled for bilateral cataract surgery an

Ferrochelatase: the convergence of the porphyrin biosynthesis and iron transport pathways

Ferrochelatase (also known as PPIX ferrochelatase; Enzyme Commission number 4.9.9.1.1) catalyzes the insertion of ferrous iron into PPIX to form heme. This reaction unites the biochemically synchronized pathways of porphyrin synthesis and iron transport in nearly all living organisms. The ferrochelatases are an evolutionarily diverse family of enzymes with no more than six active site residues kno

Healthy lifestyle index and risk of gastric adenocarcinoma in the EPIC cohort study

Several modifiable lifestyle factors, including smoking, alcohol, certain dietary factors and weight are independently associated with gastric cancer (GC); however, their combined impact on GC risk is unknown. We constructed a healthy lifestyle index to investigate the joint influence of these behaviors on GC risk within the European Prospective Investigation into Cancer and Nutrition (EPIC) cohor

Genetic parameters for rennet- and acid-induced coagulation properties in milk from Swedish Red dairy cows.

Milk coagulation is an important processing trait, being the basis for production of both cheese and fermented products. There is interest in including technological properties of these products in the breeding goal for dairy cattle. The aim of the present study was therefore to estimate genetic parameters for milk coagulation properties, including both rennet- and acid-induced coagulation, in Swe

Bovine chromosomal regions affecting rheological traits in rennet-induced skim milk gels.

Optimizing cheese yield and quality is of central importance to cheese manufacturing. The yield is associated with the time it takes before the gel has an optimal consistency for further processing, and it is well known that gel formation differs between individual milk samples. By identifying genomic regions affecting traits related to rennet-induced gelation, the aim of this study was to identif