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Vaccinations are one of the most significant interventions to public health, but vaccine hesitancy creates concerns for a portion of the population in many countries, including Sweden. Since discussions on vaccine hesitancy are often taken on social networking sites, data from Swedish social media are used to study and quantify the sentiment among the discussants on the vaccination-or-not topic du
We report the discovery of a novel neo-sex chromosome in an African warbler, Sylvietta brachyura (northern crombec; Macrosphenidae). This species is part of the Sylvioidea superfamily, where four separate autosome–sex chromosome translocation events have previously been discovered via comparative genomics of 11 of the 22 families in this clade. Our discovery here resulted from analyses of genomic
With air-photonics THz platform, we investigated photo-induced carrier dynamics of single and multilayer 2D perovskite single crystals. Interesting novel features and physics are revealed with effective conductivity spectrum up to 12 THz and 40-fs time resolution.
Background purpose: A substantial number of patients with acute ischemic stroke (AIS) experience multiple acute lesions (MAL). We here aimed to scrutinize MAL in a large radiologically deep-phenotyped cohort. Materials and methods: Analyses relied upon imaging and clinical data from the international MRI-GENIE study. Imaging data comprised both Fluid-attenuated inversion recovery (FLAIR) for white
We consider a spectral problem associated with steady water waves of extreme form on the free surface of a rotational flow. It is proved that the spectrum of this problem contains arbitrary large negative eigenvalues and they are simple. Moreover, the asymptotics of such eigenvalues is obtained.
It has long been known that the story of Barlaam and Ioasaph - or Barlaam and Iosafat as it was known in the Latin West - despite being a Christian legend is really a Buddha life that has gone through several transformations. From a probably Sanskrit original, the story passed through a Manichaean version, was turned into an Ismaelitic Muslim legend; from there it passed into a Georgian Christian
Abstract in Danish:En nærmere undersøgelse af baggrunden for de reformer, som Manuel I Komnenos (1118-80) forsøgte at indføre mod slutningen af sin regeringstid, viser at disse forsøg udsprang af en tidligere knæsat holdning i Byzans over for Islam. Hvad Manuel ønskede at gøre var at bringe sin religionspolitik i tråd hermed og med den der blev ført i det konkurrerende emirat i Ikonium (Konya), me
Background: Gallbladder cancer (GBC) is an aggressive, uncommon malignancy, with variation in operative approaches adopted across centres and few large-scale studies to guide practice. We aimed to identify the extent of heterogeneity in GBC internationally to better inform the need for future multicentre studies. Methods: A 34-question online survey was disseminated to members of the European-Afri
Parkinsons sjukdom är en kronisk neurodegenerativ sjukdom karaktäriserad avtypiska motoriska symtom i form av långsamma rörelser, muskelstelhet ochvilotremor. Dessa symtom orsakas av en brist på signalsubstansen dopamin i deområden av hjärnan som kontrollerar rörelser (hjärnbarken, basala ganglierna ochthalamus). Parkinsonmedicin, varav det mest effektiva är levodopa, mildrarsymtomen genom att ökaParkinson's disease (PD) is a neurodegenerative disorder characterised by typicalmotor symptoms that are caused by severe dopamine depletion in the cortico-basalganglia network. Parkinsonian motor symptoms are improved by dopaminergicmedications, the most effective being the dopamine precursor L-DOPA. Thiscompound exerts its motor effects by stimulating dopamine D1 and D2 receptors,whose expressio
Syftet med den här rapporten är att bidra till en ökad förståelse av handelns innovativa förmåga och att bidra till ett för handeln anpassat sätt att leda och organisera innovation. Tillsammans med de företag som har varit delaktiga i forskningsprojektet vill vi dela med oss av de utmaningar och lösningar som vi har identifierat, diskuterat och analyserat i relation till den existerande kunskapen
New approaches based on -omics technologies can identify biomarkers and processes regulated in response to xenobiotics, and thus support toxicological risk assessments. This is vital to meet the challenges associated with “cocktail effects”, i.e. combination effects of chemicals present simultaneously in a product, our environment, and/or our body. For plant protection products (PPPs), investigati
Background: Little is known about how PFAS concentrations in human milk change over the course of lactation, although this is an important determinant of cumulative infant exposure from breastfeeding.Objective: To estimate changes in PFAS concentrations in human milk over the course of lactation in a population with a wide range of exposure from background-to high-exposed.Methods: We measured PFAS
Languages differ in how grammatically salient gender is. We explored if grammatically gender-neutral pronouns in Finnish and Turkish, two grammatically genderless languages, are gender neutral or male biased, thereby activating male, rather than female, exemplars. We also tested whether differences in national level gender equality influence the male bias. Results indicated a male bias in both lan
Pediatric central nervous system (CNS) tumors represent the most common cause of cancer-related death in children aged 0–14 years. They differ from their adult counterparts, showing extensive clinical and molecular heterogeneity as well as a challenging histopathological spectrum that often impairs accurate diagnosis. Here, we use DNA methylation-based CNS tumor classification in combination with
Copy number (CN) polymorphisms of complement C4 play distinct roles in many conditions, including immune-mediated diseases. We investigated the association of C4 CN with systemic sclerosis (SSc) risk. Imputed total C4, C4A, C4B, and HERV-K CN were analyzed in 26,633 individuals and validated in an independent cohort. Our results showed that higher C4 CN confers protection to SSc, and deviations fr
This abstract describes the decomposition of a matrix representing a scattering dyadic into characteristic modes. Scattering dyadic, as compared to conventionally used impedance matrices, are independent of numerical method used to compute them and the same characteristic mode formulation can be used for decomposition of composite and inhomogeneous materials. The utilization of scattering dyadic m
It has been shown that a partially reflective surface (PRS) antenna with a larger reflection magnitude has a higher antenna gain, based on practical design examples. In this paper, PRS antennas with different reflection magnitudes are analyzed using an intuitive ray-tracing model. It is derived that the larger reflection magnitude enables a smaller phase delay and a more uniform magnitude distribu
