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ICTV virus taxonomy profile : Papillomaviridae

The Papillomaviridae is a family of small, non-enveloped viruses with double-stranded DNA genomes of 5 748 to 8 607 bp. Their classification is based on pairwise nucleotide sequence identity across the L1 open reading frame. Members of the Papillomaviridae primarily infect mucosal and keratinised epithelia, and have been isolated from fish, reptiles, birds and mammals. Despite a long co-evolutiona

What's the problem with prostitution? : Shifting problematisations of men and women selling sex

The selling or procuring of sexual services was never an uncontroversial part of the everyday exchange of goods and services in Western culture. Instead, it has been represented as a problem since (at least) the Middle Ages, and the problem descriptions have had different functions as the social, economic and cultural organisation of society was changing. Men selling sex to men, on the other hand,

In-beam internal conversion electron spectroscopy with the SPICE detector

The SPectrometer for Internal Conversion Electrons (SPICE) has been commissioned for use in conjunction with the TIGRESS γ-ray spectrometer at TRIUMF's ISAC-II facility. SPICE features a permanent rare-earth magnetic lens to collect and direct internal conversion electrons emitted from nuclear reactions to a thick, highly segmented, lithium-drifted silicon detector. This arrangement, combined with

Nanostructure and biomolecule interactions : Characterizing the complex

Nanostructures are found everywhere in our environment, of either natural oranthropogenic origin. Volcanoes emit them, breakdown of plastic releases them, andthey are even produced in candlelight. Designed nanostructures are used in sunscreen,food products, electronics and many more readily available products. Still, there are alot of things we do not know about their behavior. To call them miniscThis thesis presents the results of studies done on various biomolecules and their interactions with nanomaterials. The biomolecule sources are everything from purified, single proteins to the complicated mixture of blood serum and cell culture media. Similarly, the nanomaterial sources vary from spherical titanium dioxide, gold, and polystyrene nanoparticles to novel nanowires of gallium arsenide

High Hydrostatic Pressure Induces a Lipid Phase Transition and Molecular Rearrangements in Low-Density Lipoprotein Nanoparticles

Low-density lipoproteins (LDL) are natural lipid transporter in human plasma whose chemically modified forms contribute to the progression of atherosclerosis and cardiovascular diseases accounting for a vast majority of deaths in westernized civilizations. For the development of new treatment strategies, it is important to have a detailed picture of LDL nanoparticles on a molecular basis. Through

Epidemiology of fungaemia in Sweden : A nationwide retrospective observational survey

Objectives: To identify the epidemiology and antifungal susceptibilities of Candida spp. among blood culture isolates to identify the epidemiology and antifungal susceptibilities of Candida spp. among blood culture isolates in Sweden. Methods: The study was a retrospective, observational nationwide laboratory-based surveillance for fungaemia and fungal meningitis and was conducted from September 2

Chapter 24, The Netherlands

This chapter discusses the tax gap in the Netherlands, access to information needed by the Dutch tax administration, exchange of information between the tax administration of the Netherlands and of other countries, cooperation between the Dutch tax administration and other Dutch law enforcement agencies, cooperative compliance and risk management in the Netherlands, the way the collection of taxes

Search for new phenomena using the invariant mass distribution of same-flavour opposite-sign dilepton pairs in events with missing transverse momentum in √s=13 Te pp collisions with the ATLAS detector

A search for new phenomena in final states containing an e+e- or μ+μ- pair, jets, and large missing transverse momentum is presented. This analysis makes use of proton–proton collision data with an integrated luminosity of 36.1fb-1, collected during 2015 and 2016 at a centre-of-mass energy s=13TeV with the ATLAS detector at the Large Hadron Collider. The search targets the pair production of super

Search for pair production of heavy vector-like quarks decaying into high-p T W bosons and top quarks in the lepton-plus-jets final state in pp collisions at √s=13 TeV with the ATLAS detector

A search is presented for the pair production of heavy vector-like B quarks, primarily targeting B quark decays into a W boson and a top quark. The search is based on 36.1 fb−1 of pp collisions at s=13 TeV recorded in 2015 and 2016 with the ATLAS detector at the CERN Large Hadron Collider. Data are analysed in the lepton-plus-jets final state, characterised by a high-transverse-momentum isolated e

Spices in the postprandial metabolic regulation of healthy humans : An integrated physiological and omics approach

Metabolic syndrome (MetS) is a consequence of obesity and defined as cluster of at least three out of five criteria covering insulin resistance/glucose intolerance, abdominal obesity, hypertension, low HDL-c and elevated TG levels. Imbalance between energy intake and expenditure is known to alter normal physiological function in many aspects, and leads to obesity, which in the long run may turn in

Not all those who wander are lost : A study of cancer cells by digital holographic imaging, fluorescence and a combination thereof

Cancer är den näst vanligaste dödsorsaken i världen idag och en tredjedel av Sveriges befolkning blir diagnosticerade med cancer under sin livstid. Av alla cancerfall i Sverige, så är prostatacancer den vanligaste och bröstcancer den näst vanligaste, medan hos enbart kvinnor så är bröstcancer den vanligaste med 29,2 % av cancerfallen. Överlevnaden efter en cancerdiagnos har i Sverige ökat sedan 70Cells are commonly used in research to evaluate toxicity and efficiency of drugs. However, to further increase the usefulness of cells as well as the understandings of effects of different interventions, new methods must constantly be developed and refined. Today, many assays use end-point analysis of large populations of cells, to evaluate the research question. However, there are many cases when

Measurements of b-jet tagging efficiency with the ATLAS detector using tt¯ events at √s=13 TeV

The efficiency to identify jets containing b-hadrons (b-jets) is measured using a high purity sample of dileptonic top quark-antiquark pairs (tt¯) selected from the 36.1 fb−1 of data collected by the ATLAS detector in 2015 and 2016 from proton-proton collisions produced by the Large Hadron Collider at a centre-of-mass energy s=13 TeV. Two methods are used to extract the efficiency from tt¯ events,

Neutral pion and η meson production in p–Pb collisions at √sNN = 5.02 TeV

Neutral pion and η meson invariant differential yields were measured in non-single diffractive p–Pb collisions at sNN = 5.02 TeV with the ALICE experiment at the CERN LHC. The analysis combines results from three complementary photon measurements, utilizing the PHOS and EMCal calorimeters and the Photon Conversion Method. The invariant differential yields of π0 and η meson inclusive production are

Enhanced expression of MycN/CIP2A drives neural crest toward a neural stem cell-like fate : Implications for priming of neuroblastoma

Neuroblastoma is a neural crest-derived childhood tumor of the peripheral nervous system in which MycN amplification is a hallmark of poor prognosis. Here we show that MycN is expressed together with phosphorylation-stabilizing factor CIP2A in regions of the neural plate destined to form the CNS, but MycN is excluded from the neighboring neural crest stem cell domain. Interestingly, ectopic expres