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Introduction: Shrunken pore syndrome (SPS), originally defined by cystatin C-based estimated glomerular filtration rate (eGFRcystatin C) being less than 60% of creatinine-based estimated glomerular filtration rate (eGFRcreatinine) in the absence of extrarenal influences on the plasma levels of cystatin C or creatinine, is associated with a high increase in mortality, even in the absence of reduced
The composition and carbon nanostructure of soot are important parameters influencing health and climate effects, and the efficacy of soot mitigation technologies. We used laser-vaporization, electron-ionization aerosol mass spectrometry (or SP-AMS) to systematically investigate relationships between aerosol mass spectra, carbon nanostructure (HRTEM), and composition (thermal-optical carbon analys
The radial drift and diffusion of dust particles in protoplanetary disks affect both the opacity and temperature of such disks, as well as the location and timing of planetesimal formation. In this paper, we present results of numerical simulations of particle-gas dynamics in protoplanetary disks that include dust grains with various size distributions. We have considered three scenarios in terms
We present a new model for building up complete exclusive hadronic final states in high energy nucleus collisions. It is a direct extrapolation of high energy pp collisions (as described by Pythia), and thus bridges a large part of the existing gap between heavy ion and high energy physics phenomenology. The model is inspired by the old Fritiof model and the notion of wounded nucleons. Two essenti
Visually guided behaviour is constrained by the capacity of the visual system to resolve detail. This, in turn, is limited by the spatial resolution and contrast sensitivity of the underlying visual system. Because these properties are interdependent and vary nonuniformly, it is only possible to fully understand the limits of a specific visually guided behaviour when they are investigated in combi
The high open-circuit voltage and the slow recombination in lead-halide perovskite solar cells has been one of the main contributors to their success as photovoltaic materials. Here, we review the knowledge on recombination in perovskite-based solar cells, compare the situation with silicon solar cells, and introduce the parameters used to describe recombination and open-circuit voltage losses in
Objectives To assess the impact of extra-articular spondyloarthritis (SpA) manifestations (anterior uveitis, psoriasis and inflammatory bowel disease (IBD)), and of comorbidities, on tumour necrosis factor alpha inhibitor (TNFi) drug retention in ankylosing spondylitis (AS). Methods We identified all bio-naïve patients with AS starting a first ever TNFi July 2006 to December 2015 from the Swedish
Introduction The provision of healthcare for patients with inflammatory arthritis occurs in the context of somewhat conflicting targets, values and drivers. Therefore, there is a need for introducing 'value-based healthcare' defined as the value of patient relevant health outcomes in relation to costs. This term is a central part of tomorrow's healthcare sector, especially for rheumatic diseases,
Human Group IIA secreted phospholipase A2 (hGIIA) is an acute phase protein with bactericidal activity against Gram-positive bacteria. Infection models in hGIIA transgenic mice have suggested the importance of hGIIA as an innate defense mechanism against the human pathogens Group A Streptococcus (GAS) and Group B Streptococcus (GBS). Compared to other Gram-positive bacteria, GAS is remarkably resi
STUDY QUESTION: Is there an association between the number of oocytes retrieved for IVF, and perinatal and obstetric outcomes? SUMMARY ANSWER: No significant association was found between the number of oocytes retrieved and perinatal outcomes, while an association was found for placenta praevia and male gender. WHAT IS KNOWN ALREADY: Previous studies have shown that between 6 and 15 oocytes retrie
Objective- Revealing patterns of associations between circulating protein and lipid levels could improve biological understanding of cardiovascular disease (CVD). In this study, we investigated the associations between proteins related to CVD and triglyceride (TG), total cholesterol, LDL (low-density lipoprotein), and HDL (high-density lipoprotein) cholesterol levels in individuals from the genera
This paper presents an ongoing research project investigating the use of bibliometrics for research evaluation and resource allocation purposes, and to investigate the effects of these evaluation models on individual, organizational and political levels. A main focus has been on bibliometrics based evaluation practices. The use of bibliometrics for local resource allocation at Swedish universities
Objective To evaluate if obstructive sleep apnoea (OSA) modifies the risk of coronary heart disease, type 2 diabetes (T2D) and diabetic complications in a gender-specific fashion. Design and setting A longitudinal population-based study with up to 25-year follow-up data on 36 963 individuals (>500 000 person years) from three population-based cohorts: the FINRISK study, the Health 2000 Cohort Stud
