Popular Abstract in Swedish Inom svensk mjölkproduktion förekommer en hög frekvens av belastningsbesvär. Vid jämförelser mellan manliga och kvinnliga mjölkare har det visat sig vara stora skillnader avseende besvärsförekomst. Kvinnorna har rapporterat högre frekvens av problem i nästan alla kroppsdelar jämfört med männen. Dessutom har andelen hand- och handledsbesvär visat sig vara anmärkningsvärdThe aims of the thesis were to investigate the prevalence of the upper extremity musculoskeletal disorders in female milkers in relation to other occupational groups; to clarify the relationship between disorders and work environment, psychosocial and life style factors; to compare in a prospective study, pain, ache and discomfort reported by a questionnaire with clinical symptoms and sign; to exa

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Neisseria meningitidis lipopolysaccharide (LPS) has been identified as a major determinant of dendritic cell (DC) function. Here we report that one of a series of meningococcal mutants with defined truncations in the lacto-N-neotetraose outer core of the LPS exhibited unique strong adhesion and internalization properties towards DC. These properties were mediated by interaction of the GlcNAc(beta1

This chapter critically examines the role of networked advocacy groups in the policy making process of intellectual property rights reform. Through analysing the case of la Quadrature du Net, we question the assumption that political intermediaries or elites are dissappearing, leaving space for a more inclusive, direct democracy in which decision-makers interact more directly with citizens. Next t

Popular Abstract in Swedish Människans immunsystem utgörs av en komplex sammansättning av celler och molekyler, som interagerar med varandra men även med kroppens övriga vävnader. Dess huvudsakliga uppgift är att förse sin värd med ett försvar mot yttre och inre förhållanden, som kan orsaka denna skada, t.ex. bakterie- och virusinfektioner eller betingelser för utveckling av cancer. Denna försvarsThis thesis is based upon four original papers in which human dendritic cells (DCs) and B cells have been analyzed in terms of how they influence the character of adaptive immune responses. DCs isolated from human tonsils were found to possess a capacity to directly regulate proliferation, isotype switching, and antibody production in B cells. DC-produced cytokines, including IL-13, were identifie

There is a growing interest on Open Source Enterprise Resource Planning (OS-ERP) systems among organizations today. When developing ERP systems a major problem is requirements management. Proponents of open source development often claim it has a high level of involvement from users in adopting organizations. However, comparing with proprietary ERP development it is not that clear if users are mor

Metabolomics is a rapidly growing research field. It aims for quantification of all the metabolites in a biological sample such as plasma, saliva, cerebrospinal fluid or cells. Because the metabolite levels in a biological sample are the end result of the regulatory processes in cells, metabolomics is a very powerful approach for characterisation of phenotypes. Metabolomics has been used to find d