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Neural Stem Cell-Based Therapy for Ischemic Stroke

Stem cell-based approaches for the treatment of stroke have been the subject of intensive research over the past decade. Based on accumulated experimental evidence, stem cell-based therapy is a very promising prospect for the development of a novel treatment to restore stroke-damaged brain and impaired neurological function. Studies performed on experimental animal models of stroke employed a vari

The annual number of hip fractures in Sweden will double from year 2002 to 2050.

Background and purpose - The incidence and annual number of hip fractures have increased worldwide during the past 50 years, and projections have indicated a further increase. During the last decade, however, a down-turn in the incidence of hip fracture has been seen in the western world. We predicted the development of hip fractures in Sweden until the year 2050. Methods - We reviewed surgical re

Wall-collision line broadening of molecular oxygen within nanoporous materials

Wall-collision broadening of near-infrared absorption lines of molecular oxygen confined in nanoporous zirconia is studied by employing high-resolution diode-laser spectroscopy. The broadening is studied for pores of different sizes under a range of pressures, providing new insights on how wall collisions and intermolecular collisions influence the total spectroscopic line profile. The pressure se

Herpes Simplex Encephalitis: Lack of Clinical Benefit of Long-Term Valacyclovir Therapy.

Despite the proven efficacy of acyclovir therapy, herpes simplex encephalitis (HSE) continues to cause substantial morbidity and mortality. Among patients with HSE treated with acyclovir (ACV), the mortality rate is approximately 14-19%. Among survivors, 45-60% have neuropsychological sequelae at 1 year. Thus, improving therapeutic approaches to HSE remains a high priority.

Tracking Restorative Components: Patterns in Eye Movements as a Consequence of a Restorative Rating Task

Eye tracking was used to investigate the task of assessing how likely it is that one would be able to rest and recover in small urban spaces and how it affects the view pattern. We assess which environmental components, for example, flowers and trees, participants look at when evaluating restoration likelihood. Further, we compare number of fixations in restorative and non-restorative park photos.

Early vascular ageing in translation: from laboratory investigations to clinical applications in cardiovascular prevention.

The ageing of the vascular tree is a fundamental reflection of biological ageing in general and a determinant of organ function. In the arterial wall this is characterized by a reduction in the elastin content, as well as by an increased content of collagen and its cross-linkages, leading to increased arterial stiffness and elevated central as well as brachial blood pressure, accompanied by increa

Trust, Norms of Cooperation and the Rural Credit Market in Early Modern France

This paper looks at trust as an object of historical analysis in micro-credit exchanges at the village level before the advent of capitalism. Based on the examination of loans recorded by the notary over the course of the eighteenth century, this paper seeks to shed light not only on the mechanisms of norms of cooperation and trust but also, and more importantly, on the paradigm of trust over time

Extracting Data from WSNs: A Service-Oriented Approach

This chapter describes the architecture of a middleware layer between low-level sensing devices and higher level software layers, to support the requirements of a software infrastructure for networked enterprises. The development of such middleware layer is an important problem, as demonstrated by the number or research papers and the variety of approaches that can be found in literature. The main

How changes in coverage affect equity in maternal and child health interventions in 35 Countdown to 2015 countries: an analysis of national surveys

Background Achievement of global health goals will require assessment of progress not only nationally but also for population subgroups. We aimed to assess how the magnitude of socioeconomic inequalities in health changes in relation to different rates of national progress in coverage of interventions for the health of mothers and children. Methods We assessed coverage in low-income and middle-inc

New Tools for Understanding the Local Asymptotic Power of Panel Unit Root Tests

Motivated by the previously documented discrepancy between actual and predicted power, the present paper provides new tools for analyzing the local asymptotic power of panel unit root tests. These tools are appropriate in general when considering panel data with a dominant autoregressive root of the form ρi = 1 + ciN−κT−τ, where i = 1, ..., N indexes the cross-sectional units, T is the number of t

Identification of pregnancies at increased risk of brachial plexus birth palsy - the construction of a weighted risk score

Objective: Since it is difficult to identify women at increased risk of fetal brachial plexus birth palsy (BPBP) during labor and delivery, we aimed to construct and validate a risk score. Methods: A retrospective case-control study was undertaken in 2001 and 2006 in an urban context in Malmo, Sweden. A risk score was constructed for all women who had received routine municipal maternal health car

Comparison of species identification of endocarditis associated viridans streptococci using rnpB genotyping and 2 MALDI-TOF systems.

Streptococcus spp. are important causes of infective endocarditis but challenging in species identification. This study compared identification based on sequence determination of the rnpB gene with 2 systems of matrix-assisted laser desorption ionization-time of flight mass spectrometry, MALDI Biotyper (Bruker) and VITEK MS IVD (bioMérieux). Blood culture isolates of viridans streptococci from 63

TraML: a standard format for exchange of selected reaction monitoring transition lists

Abstract in UndeterminedTargeted proteomics via selected reaction monitoring (SRM) is a powerful mass spectrometric technique affording higher dynamic range, increased specificity and lower limits of detection than other shotgun mass spectrometry methods when applied to proteome analyses. However, it involves selective measurement of predetermined analytes, which requires more preparation in the f

Balloon Kyphoplasty for the Treatment of Acute Vertebral Compression Fractures: 2-Year Results From a Randomized Trial

Vertebral fractures are often painful and lead to reduced quality of life and disability. We compared the efficacy and safety of balloon kyphoplasty to nonsurgical therapy over 24 months in patients with acute painful fractures. Adults with one to three vertebral fractures were randomized within 3 months from onset of pain to undergo kyphoplasty (n = 149) or nonsurgical therapy (n = 151). Quality

Third world list of cetrarioid lichens - in a new databased form, with amended phylogenetic and type information

The third, updated electronic version of the world list of cetrarioid lichens (http://esamba.bo.bg.ut.ee/checklist/cetrarioid/home.php) contains more than 570 names representing 149 accepted species. It is based on a FileMaker powered database, allowing users to view data in different sets and to perform searches. The list presents new information about the phylogenetic status of accepted taxa, an

Synthesis of Substituted Oxazoles from N-Benzyl Propargyl Amines and Acid Chlorides

The reaction between N-benzylpropargylamines and acid chlorides at elevated temperatures provides efficient, direct access to a variety of di- and tri-substituted oxazoles. The versatility of this reaction is explored and 21 examples are demonstrated. The usefulness of the methodology is showcased through the short and efficient formal syntheses of medicinally relevant drugs aleglitazar and romaza

Online sexual behaviours among Swedish youth: associations to background factors, behaviours and abuse

Sexual activity online may result in positive experiences for young people, or lead them to engage in risky behaviours possibly resulting in sexual assault or abuse. The aim of our study was to investigate associations between online sexual behaviours among Swedish youth and background factors as well as aspects of wellbeing. The behaviours investigated were: having sex online with a contact met o

Hospital Admissions for Ischemic Stroke: Does Long-Term Exposure to Air Pollution Interact with Major Risk Factors?

Background: The aim was to investigate whether the effects of major risk factors for ischemic stroke were modified by long-term exposure to air pollution in Scania, southern Sweden. Methods: Cases were defined as first-ever ischemic strokes in patients born between 1923 and 1965 during 2001-2006 (n = 7,244). Data were collected from The Swedish National Stroke Register (Riks-stroke) and the Malmo