BackgroundThe elevated body swing test (EBST) is a behavioral test used to evaluate experimental stroke in rodents. The basic idea is that when the animal is suspended vertically by the tail, it will swing its head laterally to the left or right depending on lesion side. In a previous study from our lab using the EBST after middle cerebral artery occlusion (MCAo), rats swung contralateral to the i

Enzymes have come into use for many new applications outside their natural biological environment, taking advantage of their high efficiency and selectivity as biocatalysts. Such new application often requires encapsulation to preserve the structure and activity of the enzyme, but also to regulate and control the activity. Here, we will discuss two types of encapsulation, soft matrices consisting

We investigate the nature of the mid-IR excess for 31 intermediate-mass stars that exhibit an 8 μm excess in either the Galactic Legacy Infrared Mid-Plane Survey Extraordinaire or the Mid-Course Space Experiment using high-resolution optical spectra to identify stars surrounded by warm circumstellar dust. From these data we determine projected stellar rotational velocities and estimate stellar eff

This paper reports on Large Eddy Simulation (LES) of turbulent premixed methane/air flames approaching blow-off. The study focuses on a stable flame, and on a flame just prior to blow-off, both stabilized by the Cambridge bluff-body burner. For turbulence-chemistry interaction, a model based on transported probability density function (TPDF) in conjunction with Eulerian stochastic fields is used.

Laminar burning velocities of methylcyclohexane + air flames were determined using the heat flux method at atmospheric pressure and initial temperatures of 298–400 K. The measurements were performed on two experimental setups at Lund University and Samara National Research University. Our results obtained at the same initial temperatures are in good agreement. Consistency of the measurements perfo

This paper presents a search for direct electroweak gaugino or gluino pair production with a chargino nearly mass-degenerate with a stable neutralino. It is based on an integrated luminosity of 36.1 fb−1 of pp collisions at s=13 TeV collected by the ATLAS experiment at the LHC. The final state of interest is a disappearing track accompanied by at least one jet with high transverse momentum from in

At the Large Hadron Collider at CERN in Geneva, Switzerland, atomic nuclei are collided at ultra-relativistic energies. Many final-state particles are produced in each collision and their properties are measured by the ALICE detector. The detector signals induced by the produced particles are digitized leading to data rates that are in excess of 48 GB/s. The ALICE High Level Trigger (HLT) system p

This document is the final report of the ATLAS-CMS Dark Matter Forum, a forum organized by the ATLAS and CMS collaborations with the participation of experts on theories of Dark Matter, to select a minimal basis set of dark matter simplified models that should support the design of the early LHC Run-2 searches. A prioritized, compact set of benchmark models is proposed, accompanied by studies of t

Purpose: Evaluating performance of modern dose calculation algorithms in SBRT and locally advanced lung cancer radiotherapy in free breathing (FB) and deep inspiration breath hold (DIBH). Methods: For 17 patients with early stage and 17 with locally advanced lung cancer, a plan in FB and in DIBH were generated with Anisotropic Analytical Algorithm (AAA). Plans for early stage were 3D-conformal SBR

The combustibility of timber is one of the main reasons that many building regulations strictly limit the use of timber as a building material. Fire safety is an important contribution to feeling safe, and an important criterion for the choice of building materials. Historically, the combustibility aspect of wood has been a disadvantage for using timber as a construction material. The main precond

With the purpose to increase the knowledge on human behaviour when evacuating along elevated platforms, an experiment was carried out at the subway station of Skarpnäck, Stockholm, in October 2016. The overall project objective was to develop basic data for guidelines regarding fire safety design concerning evacuation along elevated platforms. The experiment was designed as a group experiment divi

A search for supersymmetric partners of gluons and quarks is presented, involving signatures with jets and either two isolated leptons (electrons or muons) with the same electric charge, or at least three isolated leptons. A data sample of proton-proton collisions at s = 13 TeV recorded with the ATLAS detector at the Large Hadron Collider between 2015 and 2018, corresponding to a total integrated

Upstream open reading frames (uORFs) are tissue-specific cis-regulators of protein translation. Isolated reports have shown that variants that create or disrupt uORFs can cause disease. Here, in a systematic genome-wide study using 15,708 whole genome sequences, we show that variants that create new upstream start codons, and variants disrupting stop sites of existing uORFs, are under strong negat

Production cross sections of muons from semi-leptonic decays of charm and beauty hadrons were measured at forward rapidity (2.5 < y < 4) in proton-proton (pp) collisions at a centre-of-mass energy s = 5.02 TeV with the ALICE detector at the CERN LHC. The results were obtained in an extended transverse momentum interval, 2 < pT< 20 GeV/c, and with an improved precision compared to previous measurem

Multi-nucleotide variants (MNVs), defined as two or more nearby variants existing on the same haplotype in an individual, are a clinically and biologically important class of genetic variation. However, existing tools typically do not accurately classify MNVs, and understanding of their mutational origins remains limited. Here, we systematically survey MNVs in 125,748 whole exomes and 15,708 whole

How mixtures of immune cells associate with cancer cell phenotype and affect pathogenesis is still unclear. In 15 breast cancer gene expression datasets, we invariably identify three clusters of patients with gradual levels of immune infiltration. The intermediate immune infiltration cluster (Cluster B) is associated with a worse prognosis independently of known clinicopathological features. Furth