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A comparison of splittings and integral equation solvers for a nonseparable elliptic equation

Iterative numerical schemes for solving the electrostatic partial differential equation with variable conductivity, using fast and high-order accurate direct methods for preconditioning, are compared. Two integral method schemes of this type, based on previously suggested splittings of the equation, are proposed, analyzed, and implemented. The schemes are tested for large problems on a square. Par

Purification of plasmid DNA with a new type of anion-exchange beads having a non-charged surface

We have prepared a new type of anion exchanger, which effectively discriminates between RNA and plasmid DNA. The material is based on a Sephacryl S-500 HR matrix provided with quartenary amine anion-exchange groups. A distinguishing feature of the beads is that a thin (2-3 mum) outer layer of the beads lacks ion-exchange groups. In the synthesis of these beads the vinyl groups in the outer layer o

Sagan om Unga Teatern i Malmö 1970-92

Popular Abstract in Swedish Avhandlingen undersöker de kontexter inom vilken Malmö Stadsteaters ungdomsgrupp Unga Teatern existerade, bl a kulturpolitik, skol- och läroplansutveckling och reception. Den övergripande frågeställningen är huruvida det under vissa perioder funnits en genomgripande estetik. Nio uppsättningar analyseras med avseende på pjästext, iscensättning, arbetsprocess och receptioThis dissertation investigates whether Unga Teatern, a theatre group for children and youth at Malmö City Theatre, had an aesthetic profile of its own. It focuses on three sections: the theme of fairy tales and myths under the artistic direction of Ronnie Hallgren (19977-83), his staging of English plays (1982 -84) and the avantgarde production for children and youth under the direction of Karin P

Increased stiffness of the abdominal aorta in women with rheumatoid arthritis.

Objective. To study the distensibility and the diameter of the abdominal aorta and the common carotid artery (CCA) in patients with rheumatoid arthritis (RA), and investigate the relation between mechanical properties of these arteries and disease severity. Methods. One hundred and one patients with RA (33 consecutive cases with extra-articular manifestations, and 68 subjects with non-extra-artic

Modeling and Model Reduction in Automotive Systems

The current control design development process in automotive industry and elsewhere involves many expensive experiments and hand-tuning of control parameters. Model based control design is a promising approach to reduce costs and development time. In this process low complexity models are essential. This thesis combines the areas of modeling and model reduction in automotive systems. A model of th

Modernitet och intermedialitet i Erik Asklunds tidiga romankonst

Modernitet och intermedialitet is the first major study of the Swedish modernist writer Erik Asklund (1908-1980) and his works. The thesis consists of an introductory chapter and three close readings of Asklund’s early novels Kvinnan är stor (The Woman is Great, 1931), Lilla land (A Small Country, 1933), and Fanfar med fem trumpeter (A Fanfare with Five Trumpets, 1934). In these novels, Asklund de

Fallbeskrivning. Rosiglitazonbehandling gav kraftfull effekt, men fick ändå avbrytas

The thiazolidinediones were introduced as oral hypoglycemic drugs in Sweden during the fall of 2000. A case is reported in which a woman with insulin-dependent type-2 diabetes and both macro- and microangiopathy and pronounced insulin resistance was treated with rosiglitazone (Avandia). Within three months insulin doses could be reduced by 36% (from 176 to 112 units insulin daily) and concomitantl

Evidence-based recommendations or "Show me the patients selected and I will tell you the results"

Modern treatment decision making in medicine is recommended to be evidence based. In order to have a high grade of evidence, the studies should have sufficient power, be randomized and double blinded. Moreover, the evaluation parameters should be solid and reproducible. While there is a lot focus on primary study design much less is focused on patient eligibility and to what extent the patients in

Human kininogens interact with M protein, a bacterial surface protein and virulence determinant.

Streptococcus pyogenes, the most significant streptococcal species in clinical medicine, expresses surface proteins with affinity for several human plasma proteins. Here we report that kininogens, the precursors to the vasoactive kinins, bind to the surface of S. pyogenes. M protein, a surface molecule and a major virulence factor-in these bacteria, occurs in > 80 different serotypes. Among 49 str

A galabiose-based two-dimensional scaffold for the synthesis of inhibitors targeting Pk- and P-antigen binding proteins.

A disaccharide scaffold based on galabiose (Gal1–4Gal) was synthesized. Four different acceptors were evaluated in the -galactosylation and a relationship between the nucleophilicity, yield, and /-selectivity was found. The scaffold contains two orthogonal derivatisation sites, i.e. at O-2′ and the anomeric position, and as proof of concept, one derivatised galabioside was synthesized. Compounds b

The importance of terrestrial carbon in plankton food webs

Allochthonous substances, i.e. produced in terrestrial ecosystems, are known to fuel bacterial production in humic lakes. I observed that allochthonous carbon subsidizes bacteria even at high levels of phytoplankton biomass. In line with that, my results also show that dissolved organic carbon is largely constituted of terrestrial substances irrespective of lake characteristics. Since bacteria co

Antibody inhibition of synaptosomal protein of 25 kDa (SNAP-25) and syntaxin 1 reduces rapid exocytosis in insulin-secreting cells.

SNARE-proteins (soluble NSF-attachment protein receptor) are important for Ca2+-dependent exocytosis. We have used capacitance measurements and confocal imaging to dissect the role of synaptosomal protein of 25 kDa (SNAP-25) and syntaxin 1 in rapid exocytosis in insulin-secreting pancreatic ß-cells. Following immunoneutralization of syntaxin 1 and SNAP-25, exocytosis was strongly reduced and assoc

Short-term effects of enhanced UV-B and CO2 on lichens at different latitudes

Interaction effects of UV-B and CO2 on three lichens species, Cladonia arbusculo, Cetraria islandica and Stereocaulon paschale, from two latitudinal sites, 68N and 56N, were studied in a laboratory experiment. The response of the plants was recorded by measuring their chlorophyll fluorescence. All species had a similar response to enhanced UV-B depending on the latitude from which the population c